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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Developing Software for Pharmacodynamics and Bioassay Studies

    SBC: TConneX Inc.            Topic: DHP16C001

    Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

    STTR Phase II 2019 Department of DefenseDefense Health Agency
  2. Wavelength-Agile Real Time Tabletop X-ray Nanoscope based on High Harmonic Beams

    SBC: Kapteyn-Murnane Laboratories, Inc.            Topic: ST15C001

    Nanoscale, material sensitive, imaging techniques are critical for progress in many disciplines as we learn to master science and technology at the smallest dimensions — on the nanometer to atomic-scale. However, progress in both science and technology is becoming increasingly limited by the constraints of current imaging techniques and metrologies. Fortunately, by combining coherent extreme UV ...

    STTR Phase II 2019 Department of DefenseDefense Advanced Research Projects Agency
  3. POC Blood Coagulopathy Monitor

    SBC: CFD Research Corporation            Topic: DHA19A001

    Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

    STTR Phase I 2019 Department of DefenseDefense Health Agency
  4. Assess Stability and Anti-Fragility of Dense Urban Terrains

    SBC: Cordillera Applications Group, Inc.            Topic: ST17C003

    The objective of this proposal is to examine the feasibility of defining and measuring key dimensions of an urban system to include its essential functions and networks, and whether they can be modelled in a computational framework for assessing robustness and resilience of DUTs (and their tipping points) under conditions of volatility and stress. This proposal will conduct a comprehensive review ...

    STTR Phase I 2018 Department of DefenseDefense Advanced Research Projects Agency
  5. CPS: Creative Problem Solver

    SBC: Smart Information Flow Technologies, LLC            Topic: N16AT002

    Military systems operate in complex, adversarial environments where their initial planned operations are often overcome by events, but soldiers use those systems in creative ways to achieve their mission objectives. For example, complex ground robotic systems that were initially deployed for surveillance and explosive ordinance disposal have instead been used as decoys, ammunition carriers, and ot ...

    STTR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  6. Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized Treatment

    SBC: BARRON ASSOCIATES, INC.            Topic: DHA17B003

    Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  7. Fast Parameter Identification for Personalized Pharmacokinetics

    SBC: Autonomous Healthcare Inc            Topic: DHP17B003

    Drug dosingcan bemademore precise by using pharmacokineticand pharmacodynamicmodeling. Pharmacokinetics is thestudy of the concentration of drugs in tissueasafunction of timeand doseschedule,whereas pharmacodynamics is thestudy of therelationship between drugconcentration and drugeffect. By relating doseto resultant drugconcentration (pharmacokinetics)and concentration to effect (pharmacodynamics) ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  8. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: Luna Innovations Incorporated            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  9. Dynamic virtual moulage based on thin film adhesive displays

    SBC: ARCHIE MD INC.            Topic: DHA17A002

    Providing Army combat medics with meaningful experience in treatment of battlefield injuries is a particular challenge. Moulage has the potential to assist in acquiring what could otherwise be very hard-to-come-by preparatory experience for distressing real-life emergencies medics and soldiers may encounter in the field. However, current approaches to moulage are limited in their ability to reflec ...

    STTR Phase II 2018 Department of DefenseDefense Health Agency
  10. Compact Integrated Silicon Nitride Microresonator Accelerometer

    SBC: APPLIED OPTRONICS CORP            Topic: ST13A002

    To solve the DARPA need for high-performance MEMS-based optomechanical accelerometers, Applied Optronics proposes to develop a Compact Integrated Silicon Nitride Microresonator Accelerometer (OPTIMA), which is based on a combination of a high-Q silicon ni

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
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