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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biological Activity Assay and Bioanalytical Test Method Development for a Silk-Derived Protein (SDP) Eye Drop Product

    SBC: SILK TECHNOLOGIES, LTD.            Topic: NonDoD

    The company has developed a silk-derived protein (SDP) for use as a novel ophthalmic formulation excipient that will help to treat the ocular injuries and dry eye pathology that affects over 40 million Americans annually and hundreds of millions of people worldwide. The SDP excipient is designed to enhance tear formulation comfort, longevity, and overall ocular health. This proposal builds on the ...

    SBIR Phase II 2019 Department of DefenseDefense Health Agency
  2. AOTF Based Spectro-Polarimetric Imaging System for Stand-off Chemical Detection

    SBC: BRIMROSE TECHNOLOGY CORP            Topic: CBD13104

    Our goal in this SBIR project is to develop a lightweight, low-power, inexpensive hyperspectral spectro-polarimetric imaging sensor for wide area standoff detection of chemical agents. The imaging system will employ an acousto-optic tunable filter (AOTF) that operates in the LWIR wavelength range. The sensor will have polarimetric imaging capabilities which, adds a valuable signature feature to im ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Open-Path Spatial Ring Down Spectrometer for Chemical Vapor Detection

    SBC: PHYSICAL SCIENCES INC.            Topic: CBD171004

    Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders as the first line of defense for personnel working in contaminated environments. Many innovative products have been developed for the chemical protective clothing market in response to demand from the market place for improved performance. However, the need for ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and 2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survival rates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  6. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: CMC PHARMACEUTICALS INC            Topic: CBD181005

    CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as a counter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  7. Field Portable Mass Spectrometry for Small Molecule Drugs in Clinical Samples

    SBC: SPECTRAL ENERGIES LLC            Topic: CBD181006

    We propose a novel two-dimensional mass spectrometry (2D-MS) technique based on ion trap arrays to identify illicit and designer drugs. This approach will give an unprecedented multiplex advantage for miniature mass spectrometry, allowing novice field technicians to rapidly identify drugs affecting the central nervous system based on both the m/z ratio and fragmentation pattern of an ion. Towards ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  8. Dual-mode T-DHM/IR Spectral Sensor for Real-time Pathogen Imaging

    SBC: PHYSICAL SCIENCES INC.            Topic: CBD171003

    Physical Sciences Inc. will develop a Tomographic Digital Holographic Microscope with integrated Infrared spectromicroscopy (T-DHM/IR) to enable time resolved correlation of chemical and 3D structural properties of biological warfare agents (BWAs), microorganisms and infected human tissue. The T-DHM/IR uses a precision hexapod stage and a custom reflective microscope objective with NA = 0.83 to pe ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  9. Automated Visual Anthropometry for Three-Dimensional Assessment of Respirators (AVATAR)

    SBC: CHARLES RIVER ANALYTICS, INC.            Topic: CBD161005

    Military respirator masks provide the Warfighter with life critical protection against chemical, biological, radiological, and nuclear (CBRN) threats. To ensure the safety, comfort, and effectiveness of the American Warfighter, it is essential that every Warfighter be assigned a respirator that is properly sized and fitted. However, current methods for sizing and fitting respirators depend on manu ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  10. In Situ Production of Biocidal Reactive Oxygen via Directed Energy

    SBC: Zeteo Tech, Inc.            Topic: NonDoD

    This effort will expand the universe of direct energy enhancers across a wider spectrum of RF parameters to produce optimal decontamination at even lower cost. During the course of the Phase II investigation proposed here, initial work will be carried out on the determination of the fundamental mechanism of decontamination of biological materials with an eye toward expanding applicability to chemi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
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