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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Novel Microfludic Device for Drug Toxicity Studies
SBC: CFD RESEARCH CORPORATION Topic: CBD10103Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants
SBC: CFD RESEARCH CORPORATION Topic: CBD10107Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
AC Impedance Sensor for Collective Protection Filter Residual Life Indicator
SBC: GUILD ASSOCIATES INC Topic: CBD10106Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...
SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense -
An automated, high throughput, resin-free device for large scale protein purification
SBC: CFD RESEARCH CORPORATION Topic: CBD12102Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense -
A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols
SBC: CFD RESEARCH CORPORATION Topic: CBD12107Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense -
Rapid Sample Transport in Austere Environments
SBC: PIASECKI AIRCRAFT CORP Topic: CBD12108Piasecki Aircraft proposes to meet the challenge of delivering a biological or chemical sample maintained at less than -20 deg Celcius over a range of up to 1000 miles with a precision landing with a portable unmanned aerial system capable of a vertical takeoff, cruise flight range typical of a fixed wing platform, and able to perform a precision landing. The system consists of a lifting quadrotor ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense -
ARCH Technology for a Simple, Resilient, and Cost-Effective Auto- Injector
SBC: AKTIVAX, INC. Topic: CBD13106A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense -
Development of a long-acting, injectable controlled release butyrylcholinesterase formulation using predictive modeling.
SBC: Qrono, Inc. Topic: CBD13107Elevated levels of human butyrylcholinesterase (BuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of BuChE in the plasma for days or weeks. Thus far, plasma-derived and PEGylated recombinant forms of BuChE have been tested in humans. However, ...
SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense -
Prototype Application of Mobile, Cloud-based, Watson-Like Technologies for TBI/PTSD Clinical Decision Support and Predictive Analytics
SBC: Lifecom Inc. Topic: DHP12005The goal of this Phase I project is to develop an engineering plan and to create a prototype for a mobile, cloud-based expert system to aid in diagnosis, decision support and predictive analytics to improve clinical outcomes for veterans, soldiers, and their families with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). Lifecom, Inc. is a health information technology compan ...
SBIR Phase I 2013 Department of DefenseDefense Health Agency -
Novel Vector Survaillance Trap for Flying Insects
SBC: TDA RESEARCH, INC. Topic: DHP12007Civilian and military organizations throughout the world perform surveillance to combat vector-borne disease. Of particular concern to the U.S. military are mosquito genera Anopheles, Aedes and Culex, which are important vectors for malaria, dengue and West Nile virus respectively, and sand fly genera Phlebotomus and Lutzomyia, both vectors for leishmaniasis. The trap most commonly used for by U.S ...
SBIR Phase I 2013 Department of DefenseDefense Health Agency