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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Therapy of transplantation-induced oxidative injury using polymeric antioxidants

    SBC: CELDARA MEDICAL, LLC            Topic: 400

    DESCRIPTION provided by applicant Ischemia reperfusion I R injury during renal transplantation surgery is responsible for oxidative stresses which result in immune activation and graft rejection We are developing an antioxidative therapy that we have already shown to be highly efficacious in ameliorating damage from oxidative stress in various in vitro models as well as I R models of kidney ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Optical imaging for radiation therapy dose verification on patients

    SBC: DOSEOPTICS LLC            Topic: 102

    DESCRIPTION provided by applicant For the first time it is possible to directly visualize a radiation beam incident upon a patientandapos s tissue in real time using Cerenkov emission imaging This imaging could transform the ease for verifying delivery in radiation oncology and allow on the fly reporting recording and correction of replanning needs or delivery errors In a field wher there ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Diagnostic Biomarkers to Predict Individual Propensity to Diabetic Complications

    SBC: PREVENTAGE HEALTHCARE, LLC            Topic: 200

    DESCRIPTION provided by applicant The diabetes epidemic and the devastating complications that accompany it have created an unprecedented worldwide medical crisis It is primarily the complications of diabetes including kidney failure blindness cardiovascular disease and neuropathy that accounts for the $ billion spent in in the US A significant problem for doctors who treat diabe ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Developing a Z-domain based latex agglutination assay for C. difficile toxins

    SBC: SAUREUS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The most common diarrhea in hospitals and nursing care facilities are attributed to toxins secreted by Clostridium difficile These toxins called Toin A TcdA and Toxin B TcdB are the primary markers for the diagnosis of C difficile associated diarrhea CDAD The gold standard for diagnosis of CDAD is isolation of the bacteria followed by cytotoxin detec ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Ultra Low Diffusivity High Temperature Insulation

    SBC: MENTIS SCIENCES INC            Topic: SB152008

    This proposal is aimed at developing an extremely light-weight and affordable Thermal Protection Systems (TPS) for use on of DARPAs Mach 10 Experimental Space plane (XS-1) and other Expendable Hypersonic Vehicles launched from the XS-1 platform. Mentis Sciences, Inc. (Mentis) proposes to partner with Aspen Aerogels, Inc. (Aspen) to develop a structurally-sound TPS by encapsulating and curing low ...

    SBIR Phase I 2015 Department of DefenseDefense Advanced Research Projects Agency
  6. Video rate optical verification tool for radiotherapy treatment plans

    SBC: DOSEOPTICS LLC            Topic: 393

    DESCRIPTION provided by applicant For the first time it is possible to directly visualize a radiation beam hitting a patientandapos s tissue or high resolution imaging of radiation delivery in water tank phantoms using Cerenkov emission imaging This allows the opportunity to do pre treatment verification at high resolution on patient verification of every delivered fraction or simply monit ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Preclinical development of inhalable glutaredoxin-1 for the treatment of IPF

    SBC: CELDARA MEDICAL, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Idiopathic pulmonary fibrosis IPF kills about persons in the United States each year There are currently around Americans afflicted with this fatal disease that typically results in death within years This year alone another approximately Americans will receive this devastating diagnosis While two recently approved drugs reduce the ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Assessment of lung function in neonates and infants

    SBC: XEMED LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Although lung disease is a major cause of morbidity in children the forced breathing maneuvers required for assessing disease spirometry cannot be performed by young children Thus characterizing the activity or monitoring the severity of pediatric lung disease in younger children is primarily qualitative based upon parental reports with little quantitati ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Flexible Pipe Couplers for Molten Salt

    SBC: BRAYTON ENERGY LLC            Topic: 06c

    Reliable, cost-competitive thermal storage is critical to the growth of the concentrated solar power market. The proposed program focuses on a key component which impacts future trough systems, addressing chronic reliability problems, and providing a pathway to higher plant operating temperatures and resulting higher efficiency. Todays solar trough plants use synthetic oil heat transfer fluids whi ...

    SBIR Phase II 2015 Department of Energy
  10. External, High-Intensity Proton Injector with Ultra-Precise Control for Fast Spot Beam Scanning PBRT

    SBC: T Antaya, LLC            Topic: 102

    DESCRIPTION provided by applicant Proton therapy particle accelerators usually cyclotrons are large and expensive devices and only about of proton therapy treatment candidates have access to proton therapy The research at Antaya Science and Technology aims to reduce the overall cost simplify the operation and increase the availability of proton therapy to all candidate patients The p ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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