Award Data

DESCRIPTION provided by applicant Medical errors are recognized as the cause of numerous deaths and even if some are difficult to avoid many are preventable Computerized physician order entry systems with decision support have been proposed to reduce this risk of medication errors but these systems rely on structured and coded information in the electronic health record EHR Unfortunately ...

DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

SUMMARY This STTR Phase II proposal addresses the significant need for improved treatment options for patients with liver cancerthe fifth highest incidence of cancer in the worldBecause of the lack of symptomshepatocellular carcinomaHCCis detected at advanced stages inof casesfor which theyear survival rate isand atyears it isThe only curative option for advanced HCC is surgical liver resection an ...

Summary We believe that our project is responsive to the HLS Small Business Topic of Special Interest for NHLBI Fiscal Year Here we will develop commercialization ready advanced functional imager to assess red blood cell RBC transfusion We successfully finished Phase I by developing the device s prototype and testing its functionality in the proof of principle experiments in scatter ...

PROJECT SUMMARY This Phase II project aims to continue development of a commercial qualityinnovative cloud hosted information management systemcalled Climbthat will increase laboratory efficiency and provide improved capabilities for research laboratoriesClimb is designed to offer integrated laboratory process management modules that include mobile communications tools data monitoring and alert sy ...

Abstract Pancreatic ductal adenocarcinoma PDAC is a devastating cancer with an extremely low year survival rate even for those who are diagnosed early Novel research suggests that this may be the result of metastatic dissemination preceding or concurrent to the development of the primary tumor Epithelial mesenchymal transition EMT is one of the key pathways in pancreatic cancer invasion ...

PROJECT SUMMARYRespiratory syncytial virusRSVis the major cause of severe lower respiratory tract infections in children and infantsaffecting an estimatedmillion people and causing up todeaths worldwide per yearWHOIn the USyoung children andadults are hospitalized annually due to RSV infectionHigh risk adultsthe elderly and patients with chronic heart or lung diseaseexperience the highest RSV attr ...

Abstract Vaccines are fundamental in preventing debilitating illnesses and saving millions of lives each year But despite these vaccine oriented victories infectious diseases are still the second leading cause of death as well as the leading cause of disability adjusted life years worldwide About six million deaths were attributed to AIDS malaria and tuberculosis in regions where no vaccine ...

DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

DESCRIPTION provided by applicant THE MEMORY CARE NAVIGATOR A PROACTIVE GUIDE Memory loss is an increasing problem as our population ages causing a tremendous personal and societal toll in disability and cost Alzheimerandapos s disease AD the most common cause of dementia is the illness elderly Americans most fear and the only major illness with an increasing mortality rate Despite subs ...