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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Universal Attenuated Sporozoite Vaccine and Challenge System

    SBC: SANARIA INC.            Topic: NIAID

    ABSTRACT Sanaria s Plasmodium falciparumPfsporozoiteSPZvaccines development program is receiving global supportTrials of PfSPZ Vaccineradiation attenuated PfSPZor PfSPZ CVacPfSPZ Chemoprophylaxis Vaccineadministered by direct venous inoculationDVIincludingadults to infants were initiated in DecemberTanzaniaU Sor will be initiated in earlyin MaliKenyainfantsGhanaEquatorial GuineaGermany andaddition ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Protease chain reactions for molecular analysis of cancer markers

    SBC: POTOMAC AFFINITY PROTEIN LLC            Topic: 102

    DESCRIPTION provided by applicant Our objective is to develop a Protease Chain Reaction technology ProCR that will enable ultra sensitive and highly quantitative detection of cancer markers The basic element of a protease chain reaction is a protease inhibitor complex The protease is inactive when bound to the inhibitor but once freed is capable of cleaving the inhibitor and releasing ad ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Software for improved accuracy and rapid tracking of kinematics from dynamic Xray

    SBC: C-MOTION, INC.            Topic: NIAMS

    DESCRIPTION provided by applicant Orthopaedic disorders are a leading cause of disability in the U S with arthritis and or spine problems adversely affecting quality of life fo more than of adults While advances in diagnostic imaging have greatly improved our ability to detect structural changes in musculoskeletal tissues they typically reveal little about joint function There is evid ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Personalized Driving Data for Insurance Discounts & Public Benefits

    SBC: AGNIK LLC            Topic: 141FH2

    This proposal suggests research on developing the next generation of consumer experience for Usage Based Insurance (UBI) in an increasingly socially connected world while addressing the need to protect privacy. It also proposes research on methodologies to address this from the perspective of insurance actuarial science. It will enhance Agnik’s current consumer and UBI products through the follo ...

    SBIR Phase II 2016 Department of Transportation
  5. Novel Mucosal Adjuvant for an HIV DNA Vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Our primary approach to develop an effective prophylactic vaccine against HIV utilizes a novel immunogen called the Full Length Single Chain FLSC that consists of gp derived from HIV genetically linked via a amino acid linker to the D D domains of human CD When rhesus macaques were inoculated with versions of FLSC that contain CD derived from rhes ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Novel DNA Launched Attenuated Vaccine for VEE Virus SBIR Phase II

    SBC: MEDIGEN, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Venezuelan Equine Encephalitis virus VEEV is a life threatening NIH NIAID category B human pathogen and a potential bioterrorism threat Outbreaks of VEEV occur in Central America and have previously spread into the United States The potentially devastating effects of the virus reemergence in the U S demand an effective vaccine to protect population Curr ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Improving vaccine development through high throughput immunogenicity screening

    SBC: Carterra, Inc.            Topic: NIAID

    Abstract Vaccines are fundamental in preventing debilitating illnesses and saving millions of lives each year But despite these vaccine oriented victories infectious diseases are still the second leading cause of death as well as the leading cause of disability adjusted life years worldwide About six million deaths were attributed to AIDS malaria and tuberculosis in regions where no vaccine ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A glycolipid adjuvant to promote dose sparing, accelerate immunization schedules and extend durability of high-level protection with a live attenuated sporozoite malaria vaccine

    SBC: SANARIA INC.            Topic: R

    DESCRIPTIONprovided by applicantThe world needs a highly effective malaria vaccineSanaria rPfSPZ Vaccinecomposed of asepticpurifiedcryopreserved radiation attenuated PfSPZprotectedof volunteers in an NIH clinical trialThe vaccine has been administered by direct venous inoculationDVItosubjects in MaliTanzaniaEquatorial GuineaEGand USASafetytolerabilityhigh grade protectionheterologous protection af ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: LIVE INSPIRED LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. A Probabilistic Pose Estimation Algorithm for D Motion Capture Data

    SBC: C-MOTION, INC.            Topic: NICHD

    DESCRIPTION provided by applicant Orthopaedic disorders are a leading cause of disability in the U S with arthritis and or spine problems adversely affecting quality of life fo more than of adults With an aging population the rate of disability from orthopaedic disorders has been increasing steadily While advances in diagnostic imaging including CT MRI and ultrasound have greatly im ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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