Award Data

THIS PROJECT ADDRESSES THE DEVELOPMENT AND EVALUATION OF A PROTOTYPE LASER RAMAN SCATTERING GAS SENSOR. POTENTIAL APPLICATION AREAS ARE: BLOOD PO2/PCO2 VIA SUITABLE SAMPLING CATHETER AND NONINVASIVE MONITORING OF RESPIRATION, ANESTHESIA DELIVERY, LUNG FUNCTION, AND CARDIAC OUTPUT. MASS SPEC, WHILE CURRENTLY THE MOST POPULAR APPROACH TO MEDICAL GAS QUANTITATION, SUFFERS FROM INHERENT USER UNFRIENDL ...

DESCRIPTION (provided by applicant): Rare-event imaging has profound implications for the early identification of potentially correctable terminal diseases, especially for cancer. What is required is a highly accurate "routine" test to be given to all

A SYSTEM UTILIZING THE FREE-WING CONCEPT HAS BEEN DESIGNED FOR LIGHT AND VERY LIGHT WING-LOADING AIRCRAFT THAT ACCOMMODATES MODERATE TO HEAVY TURBULENCE WITHOUT TRANSMITTING HIGH GUST LOADINGS TO THE AIRFRAME OR THREATENING LOSS OF CONTROL. THE PROJECT WILL TEST THE SYSTEM IN A RESEARCH VEHICLE APPROXIMATING THE DESIGN CRITERIA SET FORTH IN 14 CFR, PART 103; THE RESEARCH VEHICLE IS UNMANNED.

DESCRIPTION (provided by applicant): An innovative instrument for measuring exhaled compounds was demonstrated in Phase I of this project. The novel breath monitor (Breathmeter TM) consists of a tunable mid-IR diode laser, a long optical resonator, and el

THE DETECTION AND CHARACTERIZATION OF PESTICIDES, INDUSTRIAL SOLVENTS, AND THEIR METABOLITES IN BODY FLUIDS AND TISSUES ARE IMPORTANT FOR EVALUATING THE POTENTIAL LONG-TERM HEALTH EFFECTS OF THE EXPOSED POPULATION. UNFORTUNATELY, ANALYTICAL METHODS PRESENTLY AVAILABLE ARE GENERALLY TEDIOUS, TIME-CONSUMING, COMPLEX OR NONSPECIFIC AND LACK REQUIRED SENSITIVITY. THIS STUDY WILL EVALUATE CAPILLARY SUP ...

THE ANALYSIS OF CANNABINOIDS FOR RESEARCH OR SCREENING FOR CANNABIS ABUSE REQUIRES METHODS CAPABLE OF CHARACTERIZING AND QUANTIFYING METABOLITES OF THE CANNABINOIDS WHICH ARE GENERALLY POLAR OR THERMALLY UNSTABLE AND WHICH MUST BE SEPARATED FROM A COMPLEX BIOLOGICAL MATRIX. SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC) IS PROPOSED AS A METHOD WHICH IS CAPABLE OF PROVIDING HIGH-RESOLUTION SEPARATION OF ...

A MULTICHANNEL TUBULAR DEVICE CONTAINING ULTRA-THIN WALLED TUBES, PERMEABLE TO O2 AND CO2, WILL BE DESIGNED AND FABRICATED FOR USE AS AN EXTRAPULMONARY BLOOD GAS EXCHANGE DEVICE. THE PRODUCT IS INTENDED TO BE INSERTED INTO THE SUBJECT'S VENA CAVAL SYSTEM, ENTERING INTO THE RIGHT COMMON FEMORAL VEIN AND EXITING FROM THE RIGHT EXTERNAL JUGULAR VEIN. OXYGEN IS PASSED THROUGH THE LUMINA OF THE HOLLOW ...

DESCRIPTION (provided by applicant): Antibacterial resistant Staphylococcus aureus, in particular methicillin-resistant S. aureus (MRSA), infections constitute a serious worldwide health problem. MRSA infections are usually hospital-acquired, although the

DESCRIPTION (provided by applicant): This proposal describes assessment of the clinical utility of a quantitative molecular assay using patented monoclonal antibodies, fluorescence, analytical software, and flow cytometry technology for a white blood cell

Abstract Vaccines are fundamental in preventing debilitating illnesses and saving millions of lives each year But despite these vaccine oriented victories infectious diseases are still the second leading cause of death as well as the leading cause of disability adjusted life years worldwide About six million deaths were attributed to AIDS malaria and tuberculosis in regions where no vaccine ...