Award Data

DESCRIPTION (provided by applicant): Antibacterial resistant Staphylococcus aureus, in particular methicillin-resistant S. aureus (MRSA), infections constitute a serious worldwide health problem. MRSA infections are usually hospital-acquired, although the

Abstract Pancreatic ductal adenocarcinoma PDAC is a devastating cancer with an extremely low year survival rate even for those who are diagnosed early Novel research suggests that this may be the result of metastatic dissemination preceding or concurrent to the development of the primary tumor Epithelial mesenchymal transition EMT is one of the key pathways in pancreatic cancer invasion ...

The BMDS is being developed as a fully integrated, layered defense capable of defending against all ranges of threats. A critical aspect of this development is an integrated approach to interceptor allocation. A model-based framework for optimizing multi-layer BMDS performance, developing interceptor firing doctrine, and providing for adaptive, real-time interceptor allocation was developed in P ...

PROJECT SUMMARY This Phase II project aims to continue development of a commercial qualityinnovative cloud hosted information management systemcalled Climbthat will increase laboratory efficiency and provide improved capabilities for research laboratoriesClimb is designed to offer integrated laboratory process management modules that include mobile communications tools data monitoring and alert sy ...

To address the Anti-Submarine Warfare (ASW) training challenge of teaching Navy sonar operators advanced concepts and tactical-system operation in complex environments given constraints on training and compressed training cycles, Applied Research in Acoustics LLC (ARiA) has developed and evaluated the feasibility of E-SAIL, the Environment for Surface ASW Interactive Learning. E-SAIL is a unique l ...

A high performance low cost upper stage and demonstration of a low cost engine with a recurring cost of $1 million delivered cost.

Applied Research in Acoustics LLC has formulated and developed and evaluated the feasibility new concepts and algorithms for data-driven clutter-adaptive waveform synthesis and CFAR normalization processing based on physical models of resonant backscattering from heterogeneous aggregations of swim-bladder-bearing fish that will significantly improve active sonar detection capability in littoral wa ...

DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

DESCRIPTION (provided by applicant): Approximately 30,000 people in the United States are diagnosed each year with pancreatic cancer (PanCa). Over 90% of these will die of the disease making PanCa one of the most devastating human malignancies. The c