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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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sHLA Protein Chip
SBC: GENOMICS USA, INC. Topic: NIAIDAbstract: “sHLA Protein Chip” The class I [A, B, C] and class II HLA proteins [DRB1, DQ, DP] comprise the heart of the inducible human immune system. For organ, marrow and stem cell transplantation, the development of serum-born antibodies against one or more of those many HLA proteins comprises the best and earliest test for transplant rejection. Because of the enormous medical importance of ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Resilient Wayside Structures to Reduce Severity of Passenger Equipment Collisions and Derailments
SBC: PROTECTION ENGINEERING CONSULTANTS LLC Topic: 171FR3Proposal title: Resilient Wayside Structures to Reduce Severity of Passenger Equipment Collisions and Derailments Additional passenger fatalities/injuries can occur during derailments involving interaction with wayside structures. Analogously, automobile fatalities often result from interaction of vehicles with roadside structures; personnel hazard reduction is a key design criterion for roadsid ...
SBIR Phase II 2018 Department of Transportation -
Development of Taenia Solium Specific Aptamers for Diagnostic Assays
SBC: LYNNTECH INC. Topic: ODCDCThe parasitic tapeworm Taenia solium causes two diseasestaeniasisadult worm in the intestineand cysticercosistissue infection by the cystwhich can lead to seizuresThe Tsolium life cycle involves both humans and pigshowever humans are the only definitive host for the adult Tsolium tapewormDiagnosing people infected with the adult worm is a critical step toward eliminating Tsolium althogetherHowever ...
SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention -
Topic 346: Targeted Radionuclide Therapy of Neuroendocrine Tumors Using 212Pb-octreotate Analogs
SBC: RADIOMEDIX, INC. Topic: NCIA peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Topic 380- QIDS: Using Radiomics to Impact Radiotherapy Treatment Planning- Moonshot
SBC: HealthMyne, Inc. Topic: NCIHealthMyne proposes developing a Clinical Decision Support tool to be used in the point-of-care workflow for the Radiation Oncologist that uses radiomic features that have evidence-based association to disease course and/or normal organ damage, in order to impact the treatment planning process. Phase 1 will focus on extraction, calculation, and validation of identified radiomic features for lung c ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Topic 379: Extensible and Scalable Platform for Data Integration from Wearable Sensors to Generate Novel Analytics for Cancer Patients
SBC: Litmus Health, Inc. Topic: NCIThe longterm objective of the Litmus Health platform is to allow researchers and clinicians to use data on cancer patients from wearables/sensors and smartphones. Collecting real-time, high-quality data from patients will transform care and clinical trials. Automating data collection, storage, analysis, and interpretation of data will result in better measurement of signs and symptoms and improved ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Topic 372: Highly multiplexed selection of aptamers to hundreds of canine immunotherapy targets
SBC: BASE PAIR BIOTECHNOLOGIES INC Topic: NCIThe preclinical development of cancer therapeutics, including the recent trend and focus on cancer immunotherapies, is evolving from the traditional use of mouse models to the use of other animal models including canine, rat, and minipig. Each of these non-mouse models carries its own advantages and abilities to increase the clinical relevance of the model as compared to mouse models. Yet, the wid ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
In situ assay for RNA decapping in tumors
SBC: VIVID TECHNOLOGIES INC Topic: 102In situ assay for RNA decapping in tumors Abstract This project aims to introduce a new histotechnology to assess tumor cell stress and cell death propensitywhich can be useful in evaluating cancer response to therapyThe adaptive response of tumor cells to stress and their survival in hostile environments are signaled by the levels of mRNA decayIncreased decay dumps important mRNAs and marks cells ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Computerized Screening for Comorbidity in Adolescents with Substance or Psychiatric Disorders
SBC: KOBAK, KENNETH A Topic: 104Project Summary This is a supplementalrenewalgrant to the Phase II SBIR grantComputerized Screening for Comorbidity in Adolescents with Substance or Psychiatric DisordersSince the funding of the Phase I granttwo significant developments occurred in the fieldthe American Psychiatric Association s release of the DSMmanualand NIMH s launch of the Research Domain CriteriaRDoCinitiative that aims to cr ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Polyketide chiral building blocks and biocatalysts
SBC: Coala Biosciences Topic: 300PROJECT SUMMARY As with most synthetic chemistsCoALA Biosciences is inspired by naturally occurring polyketide assembly lineswhich synthesize diverse medicines through reactions that generate carbon carbon bonds and precisely set stereocentersIf chemists were to collaborate with the enzymes in these assembly linessyntheses of compounds in the drug discovery process would be greatly accelerated and ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health