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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. THERMOPLASTIC ELASTOMER (TPE) CHEMICAL PROTECTIVE (CP) GLOVES BY INJECTION MOLDING PROCESS

    SBC: Eskay Assoc.            Topic: N/A

    THERMOPLASTIC ELASTOMER (TPE) BY INJECTION MODLING OFFERS AN ALTERNATE METHOD FOR FORMING CHEMICAL PROTECTIVE GLOVES A SOCMPARED TO THE CONVENTONAL DIP PROCESS USING BUYTL RUBBER SOLUTIONS. THE ADVENT OF VARIOUS TPES WITH OLEFINIC, STYRENIC, URETHANE, ENGINEERING RESINS AND ALLOYS AND BLENDS OFFER THE ADVANTAGE OF INJECTION MODLING PRODUCTS WHICH HAVE BEEN CONVENTIONALLY MADE BY ELASTOMER COMPOUND ...

    SBIR Phase I 1992 Department of DefenseArmy
  2. ELECTRO-MECHANICAL (EM) ACTUATOR DRIVER

    SBC: Advanced Motion Controls Inc.            Topic: N/A

    THE PROJECT WILL DEVELOP A NOVEL MINIATURE PULSE WIDTH MODULATED POWER DRIVER FOR ACTUATORS, I.E. DC MOTOR. THE POWER DRIVER WILL DELIVER 50 AT 50VDO IN A DOUBLE INON PACKAGE. THIS COMPACT DESIGN CAN ONLY BE ACHIEVED THROUGH THE INNOVATIVE COMBINATION OF MODER POWER SEMICONDUCTOR TECHNOLOGIES, PROPRIETORY CIRCUIT DESIGN, AND STATE-OF-THE-ART PACKAGING TECHNOLOGY WHICH UTILIZES NEW HEAT CONDUCTIVE ...

    SBIR Phase II 1992 Department of DefenseArmy
  3. IMINOBIOTINYLATED DIDEOXYNUCLEOTODES FPR DNA SEQUENCING

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    A VARIETY OF DIFFERENT APPROACHES ARE BEING TAKEN TO INCREASE THE SPED AND DECREASING THE SPEED AND DECREASE THE COST OF DNA SEQUENCING. ONE OF THE MAJOR CURRENT SEQUENCING TECHNOLOGIES IS THE DIDEOXYNUCLEOTIDE CHAIN-TERMINATING APPROACH ORIGINALLY DEVELOPED BY SANGER. WE WILL USE A VARIANT OF THIS APPROACH IN WHICH THE DIDEOXYNUCLEOTIDES WILL BE MODIFIED WITH AN IMINOBIOTIN GROUP. IMINOBIOTIN BIN ...

    SBIR Phase I 1992 Department of Health and Human Services
  4. TECHNOLOGY FOR DETECTION OF SINGLE BASE MUTATIONS

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Health and Human Services
  5. DEVELOPMENT OF AN ELECTROMECHANICAL TOTAL ARTIFICIAL HEART (TAH)

    SBC: American Biomed Inc            Topic: N/A

    AN ELECTROMECHANICALLY DRIVEN TOTALLY IMPLANTABLE TOTAL ARTIFICIAL HEART (TAH) WAS DEVELOPED RECENTLY AT BAYLOR COLLEGE OF MEDICINE. THIS EXPERIMENTAL PROTOTYPE WAS PROVED TO BE RELIABLE AND EFFECTIVE, YET SMALL ENOUGH TO IMPLANT INSIDE THE CHEST CAVITY OF AN AVERAGE HUMAN PATIENT. THIS TAH SYSTEM WAS ASSEMBLED BY SELECTING AND COMBINING THE BEST, SIMPLEST AND MOST RELIABLE FEATURES AVAILABLE FROM ...

    SBIR Phase I 1992 Department of Health and Human Services
  6. SOFTWARE FOR COMBINED MEG AND MAGNETIC RESONANCE IMAGING

    SBC: AMERINEX APPLIED IMAGING, INC.            Topic: N/A

    CLINICAL USE OF MAGNETOENCEPHALOGRAPHIC (MEG) DATA WILL DEPEND UPON A VARIETY OF FACTORS, ONE OF WHICH IS THE RAPID DISPLAY OF ELECTRICAL SOURCES THAT PRODUCE SIGNALS WITHIN THE BRAIN. CURRENTLY, SINGLE DIPOLE APPROXIMATIONS OF THE SOURCE LOCATION ARE OVERLAID ON TWO-DIMENSIONAL MAGNETIC RESONANCE IMAGES (MRI) FOR DISPLAY OF THE UNDERLYING ANATOMY. THIS PROCEDURE IS SLOW AND IS A CRUDE APPROXIMATI ...

    SBIR Phase I 1992 Department of Health and Human Services
  7. CORDLESS LIGHT PEN AND INTERFACE AUTHORING SYSTEM

    SBC: APPLIED HUMAN FACTORS INC            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Health and Human Services
  8. FEASIBILITY OF PRECLINICAL SCALEUP OF LIPOSOMAL TNF

    SBC: Argus Pharmaceuticals Inc            Topic: N/A

    IN THIS PHASE I EFFORT, WE WILL DEMONSTRATE THE ABILITY TO SCALE UP THE PRODUCTION OF A LEAD LIPOSOMAL FORMULATION CANDIDATE OF ACYLATED, LIPOPHILIC RHUTNF. WE WILL SUBJECT THE BACTERIAL RECOMBINANT PROTEIN TO ACYLATION WITH THE N-HYDROXYSUCCUNIMIDE ESTER OF CAPRYLIC ACID (C3) TO ACHIEVE LIMITED SUBSTITUTION (1.5 TO 2 RESIDUES PER TNF TRIMER). THE IDENTITY AND EXTENT OF SUBSTITUTION OF THE TARGET ...

    SBIR Phase I 1992 Department of Health and Human Services
  9. DEVELOPMENT OF OPTIMUM CONDITIONS FOR NIMC PRODUCTION

    SBC: Argus Pharmaceuticals Inc            Topic: N/A

    MITOCHONDRIAL RESPIRATION INHIBITION IN TUMOR CELLS MAY OCCUR IN TWO MANNERS. ONE MECHANISM INVOLVES THE SYNTHESIS OF NITRIC OXIDE (NO) BY MACROPHAGES OR IFN-GAMMA MEDIATED INDUCTION OF NO SYNTHESIS IN TUMOR CELLS. WE HAVE RECENTLY ESTABLISHED A MURINE MACROPHAGE CELL LINE, EA13.5, THAT RELEASES A SOLUBLE MEDIATOR, NIMC, THAT CAUSES TUMOR CELL RESPIRATION INHIBITION INDEPENDENT OF NO PRODUCTION AN ...

    SBIR Phase I 1992 Department of Health and Human Services
  10. GPS-BASED AUTONOMOUS SPACE NAVIGATION

    SBC: Arrowsmith Technologies Inc            Topic: N/A

    COMMERCIAL AND GOVERNMENT SPACE TRANSPORTATION SYSTEMS DEPEND ON GROUND SUPPORT FOR NAVIGATION. THE GROUND SOLUTION CAN BE COSTLY AND MAY PROVIDE LESS ACCURACY THAN NEEDED. A GPS-BASED REAL-TIME AUTONOMOUS SPACECRAFT NAVIGATION SYSTEM IS PROPOSED. AN ALGORITHM WILL BE DEVELOPED WHICH COMBINES GPS-DERIVED POINT POSITION ESTIMATES WITH A PROPAGATED A PRIORI POSITION ESTIMATE. THE POINT POSITIONS ARE ...

    SBIR Phase I 1992 Department of Transportation
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