Award Data

There exists a wide-range need in both industry and government for quantitative residual stress measurements. Generation 2 Materials Technology LLC (G2MT) will collaborate with partners from industry and government to calibrate and commercialize the eStress system to assess residual stress from mechanical damage and re-rounding. The industrial members, consortiums, and government laboratories who ...

Low or narrow bridges are often hit by legal-sized commercial vehicles and oversize vehicles often strike regulation bridges. In both cases the accidents result in extensive property damage, possible personal injuries and even death, and increased traffic congestion. Past attempts to warn drivers of risks for bridge hits have failed due to inaccurate measurement, high rates of false alarms, or s ...

Job related injuries cost the railroads over $1 billion annually and from 2005 through 2008 30.3% of those injuries occurred in the rail yard. A majority of the accidents were attributed to slips, trips and falls from the worker slipping on ballast or tripping on other trackside objects. IEM is developing a Transportation Autonomous Device that may be configured to work autonomously, with a remote ...

DESCRIPTION (provided by applicant): The U.S. CDC estimates that each year roughly 1 in 6 Americans (or 48 million people) gets sick, 128,000 are hospitalized, and 3,000 die of foodborne illnesses. The costs in lost productivity and increased health carecosts are enormous, in addition to the consequences to individuals and families from missed work and schooling, disrupted family life, and pain an ...

DESCRIPTION (provided by applicant): Alcoholic and non-alcoholic liver fibrosis remains an unsolved challenge for the hepatologist as it can lead to cirrhosis and end-stage liver disease, a life-threatening condition that necessitates liver transplantation. Current therapeutic strategies for the treatment of liver fibrosis include changes in diet, life-style and/or medications to allevate the unde ...

DESCRIPTION (provided by applicant): The final objective of this Phase II SBIR is to complete preclinical studies of a trivalent adenoviral vaccine against plague in preparation for human clinical trials. The plague vaccine project was selected in responseto the growing concern surrounding the organism's possible use in a terrorism event. The NIAID and CDC, in response to this threat, has cla ...

DESCRIPTION (provided by applicant): There remains a critical need for medicines that can counteract the toxic effects of radiation exposure. Terapio is developing a recombinant protein, RLIP76, for use as a radioprotectant for workers, military personnel, or civilians that are either in imminent danger of radiation exposure, or have already been exposed. In research carried out at the Unive ...

DESCRIPTION (provided by applicant): Respiratory infections have a significant health and economic impact worldwide. Current test products for the diagnosis of respiratory viral infections such as influenza are inadequate for the timely diagnosis needed for successful implementation of antiviral treatment. Unfortunately a test product that can accurately diagnose common respiratory viruses with hi ...

DESCRIPTION (provided by applicant): 100,000 Americans perish each year due to untreatable bacterial infections. The societal benefits of new antibiotic compounds that are effective against numerous multiple drug resistant pathogens would be significant. The best possible source for new antibiotic structures with potentially novel mechanisms of action is within natural environments, particularly s ...

DESCRIPTION (provided by applicant): With recent radiation release from reactors in Japan and increasing probability of nuclear detonation somewhere in the world, there is a critical need for development of effective medicinal counter-measures that can bedelivered after exposure to prevent radiation-induced mortality. Adding to this need, mortality increases significantly when radiation is combine ...