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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of a rapid diagnostic assay for Myasthenia Gravis
SBC: ATTOGENE CORPORATION Topic: 101Project Summary AbstractThe physiological effect of autoantibody binding to the motor endplate junction nicotinic acetylcholine receptorsAchRcauses numerous symptoms associated with Myasthenia GravisMGand is characterized by drooping of one or both eyesblurred or double visionchange in facial expressiondifficulty swallowingshortness of breathimpaired speech and weakness of muscle functionIn some c ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development and Optimization of MNK Inhibitors for the Treatment of Neuropathic Pain
SBC: 4E THERAPEUTICS, INC. Topic: 104Abstract The goal of this project is to develop an optimized MNK inhibitor for neuropathic pain treatment. MNK is a kinase that phosphorylates eIF4E to control the translation of a distinct subset of mRNAs. Our focus on this target for neuropathic pain is grounded in evidence that MNK-eIF4E signaling is activated in nociceptors upon exposure to pain promoting cytokines and growth factors as well a ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Advance Early Detection of Lupus Nephritis with ClearGold
SBC: CLEARNANO INC Topic: 400SummarySystemic lupus erythematosusSLEor lupus is an autoimmune disease that impacts more thanmillion people worldwideincludingmillion AmericansNearlyof these patients will develop lupus nephritiswhich can cause kidney failureAs a resultits financial burden to individual patient can reach $yearmuch higher than many other diseases because of kidney transplantationAlthough early treatment of lupus n ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Novel Strategies for Development of a Multiplexed Test with Expanded Content for Spinal Muscular Atrophy
SBC: ASURAGEN, INC. Topic: 102SummaryThe overall goal of this project is to develop a cost effective multiplexed diagnostic test for spinal muscular atrophySMAto rapidly and accurately analyze multiple classes of disease causingdisease modifying DNA variantsand carrier status markersUltimatelythe proposed test will have a far reaching impact by expanding the identification and stratification of patients who may benefit from ne ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
STTR Phase I Development of Novel Antibacterial and Antifungal Bioadhesive Biomaterials for Diabetic Skin Wound Healing
SBC: DYNAMIC ENTROPY TECHNOLOGY, LLC Topic: NIDDKAbstract Diabetic ulcers or pressure ulcers are common for patients with diabetesspinal cord injuriesetcWithout proper managementsuch wounds often lead to infections such as osteomyelitis or sepsisresulting in high mortality and morbidityIn addition to bacterial infectiondiabetic patients are also more susceptible to cutaneous fungal infectionsAdvanced wound dressings and advanced wound therapies ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Preclinical studies to validate the efficacy of novel mechanism-of-action small molecule inhibitors to treat Duchenne muscular dystrophy
SBC: RIDGELINE THERAPEUTICS LLC Topic: NIAMSProgressive muscle weakness and degeneration is a hallmark of Duchenne muscular dystrophyDMDIn DMD patientsthe lack of dystrophin reduces muscle fiber structural integritymaking muscles vulnerable to persistent injury and damageRepairing these damaged muscles requires the continual activation of muscle stem cellsmuSCwhich leads to muSC dysfunction and senescenceand ultimately the muscle degenerati ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Transcutaneous auricular neurostimulation for neonatal abstinence syndrome
SBC: SPARK BIOMEDICAL INC. Topic: R43Neonatal abstinence syndromeNASis a condition in which infants undergo withdrawal after exposure to prescription or non prescription opioids such as methadone or heroin in uteroNAS babies exhibit hyperirritability of the central nervous system and respiratorygastrointestinaland autonomic symptomsThese symptoms usually appear withintohours after birthAs ofan infant with NAS was born everyminutes in ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons
SBC: SensoDX II, LLC Topic: NIDAAbstract Opioid abuse disorder (OAD) affects 2.1 million of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortality. In addition to its enormous social impact, OAD carries a multi-billion-dollar price tag that includes $78.5 billion, specifically for health care and other costs related to prescription opioid abuse and misuse. Although effect ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Incubator-based active noise control system validation in realistic NICU environment
SBC: Invictus Medical, Inc. Topic: NIDCDThe aural stimulation of the hospitalized infant in the neonatal intensive care unitNICUfrom alarmsventilatorsphonesconversationsand air handling system is linked to a myriad of problemsboth acute and long termThe stress resulting from the noise has a negative effect on vital signsweight gainand quality of sleep in the short term and in the long term with hearing loss and language deficitEfforts t ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Accelerating Functional Maturation of Human Neurons for High-Throughput Screening
SBC: BrainXell, Inc Topic: 44Project Summary/AbstractNeurological and psychiatric disorders, including drug abuse and addiction, exert a devastating personal and economic toll on patients, families, caregivers, and society. This is in part due to our failure in developing effective medications, which in turn is due to the use of drug discovery platforms that are often not relevant to target diseases. The recent development of ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health