Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. DEVELOPMENT OF NOVEL PDE4B INHIBITORS TO TREAT ALCOHOL USE DISORDER (SBIR PHASE II)

    SBC: CODEX BIOSOLUTIONS            Topic: NIAAA

    Development of Novel PDE B Inhibitors to Treat Alcohol Use Disorder

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. SBIR TOPIC 97- PHASE II- MINIMALLY INVASIVE TEST FOR CHEMOTHERAPY-INDUCED CARDIOTOXICITY

    SBC: ACCEL DIAGNOSTICS, LLC            Topic: NHLBI

    Cardiovascular toxicityCVTxis a serious short and long term complication of many anti cancer chemotherapeutic regimensZamoranoLancellotti et alIn this PhaseSBIR submission to continue the development and validation of Accel Diagnosticsminimally invasiverapidcost effective and connected blood testthe pScreen CVTx TMfor the early detection and continuous of chemotheropy induced CVTx

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Low Cost Integrated Method for Isolation of M. Tuberculosis DNA from Raw Sputum

    SBC: AKONNI BIOSYSTEMS INC.            Topic: NIAID

    Nucleic acid testing offers the potential to improve tuberculosis diagnosis world wideHigh purity DNA is essential to the success of virtually any downstream nucleic acid detection methodWe propose to develop a sample preparation system to extract and purify Mycobacterium tuberculosis DNA from raw sputumThe project goalas described in the solicitationPHSTopicis to develop an inexpensive and easy t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced development of a novel nanoparticle conjugate vaccine for Salmonella Paratyphi A

    SBC: KJ Biosciences LLC            Topic: NIAID

    Salmonella Paratyphi ASParatyphi Ais a major cause of life threatening enteric feverThere is no vaccine available against this pathogenIn the SBIR phase I studieswe have successfully demonstrated the technical feasibility of a novel nanoparticle conjugate vaccine candidate for SParatyphi AIt is based on O polysaccharideOPSantigen conjugated to a novel and highly advantageous nanoparticle protein c ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC #355- SBIR PHASE II- A 3D PERFUSABLE PLATFORM FOR HTS ACROSS DIVERSE RACIAL/ETHNIC CANCER SPE

    SBC: MIMETAS US, INC            Topic: NCI

    Prostate cancerPCaincidence and mortality in African American men is two times greater than men of other races ethnicities in the United StatesElucidating the underlying mechanisms for this cancer health disparityCHDis critical to patient treatment and improved patient outcomehowever there are no in vitro models available to adequately recapitulate the PCa tumor microenvironment across races ethni ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC 368: TREATMENT OPTIMIZATION BY COMBINED A-EMITTER (ARPT)/RADIOTHERAPY (XRT) DOSIMETRY FOR PROSTATE CANCER PATIENTS

    SBC: RADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC            Topic: NCI

    We propose to demonstrate a cloud based software service for Combination alpha emitter radiopharmaceutical therapyRPTand external beam radiotherapyXRTCX RPTtreatment planningBoth modalities deliver radiationWe will demonstrate feasibility clinically by collecting the data needed from an existing Hopkins trial evaluating combination XRT with XofigoRa dichlorideanRPT that concentratesparticle radiat ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 345: PREDICTIVE BIOMARKERS OF PROSTATE CANCER PATIENT SENSITIVITY FOR RADIATION LATE EFFECTS

    SBC: Shuttle Pharmaceuticals, Inc.            Topic: NCI

    To address the goals of developing ""predictive biomarkers of adverse reactions to radiation treatment""we propose to perform a multi site analytic validation of the product""metabolite panel kit""developed in the Phase I SBIR effortResults of plasma metabolite analysis in defined cohorts of patients treated with SBRT for prostate cancer will be tested for precisionaccuracy and reproducibility in ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. SBIR TOPIC 354: A NOVEL PREDICTIVE TEST FOR RESPONSE TO COMBINATION IMMUNOTHERAPIES FOR PATIENTS WITH NON-SMALL CELL LUNG CANCER (NSCLC)

    SBC: Biomarker Strategies, LLC            Topic: NCI

    In the proposed Phase II studywe will further develop our PathMAPImmunotherapy test to address an unmet clinical need within the NSCLC patient populationWe hope to create a test that is able to accurately predict clinical response to PDPD Ltargeted immune checkpoint inhibitors alone and in combination with chemotherapiesOur development work in Phase II will be based on our initial work performed i ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. T3 Platform: the next generation tactile tablet

    SBC: Touch Graphics, Inc.            Topic: na

    This project introduces T3, a system for creating, distributing, and consuming touch-responsive, audio-embedded tactile graphic maps, games, puzzles, and interactive lessons. Based on the successful but outdated Talking Tactile Tablet (TTT) paradigm, this new approach solves several shortcomings of earlier products, and seeks to reach new markets beyond the original target of students who are blin ...

    SBIR Phase II 2019 Department of Health and Human Services
  10. Machine Vision System to Support Vehicle to Infrastructure (V21) Safety Applications

    SBC: Intelligent Automation, Inc.            Topic: 18FH1

    To keep drivers and passengers of vehicles safe, especially in rural areas with limited access to Information and Communications Technology (ICT), the DOT and the commercial automotive industry are keenly interested in machine vision based V2I and CAV technology to perform functions such as navigating assistance in areas where GPS or detailed maps are unavailable, caution and warning systems capab ...

    SBIR Phase II 2019 Department of Transportation
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