Award Data

Project Summary Opioids like morphine and hydrocodone are generally the most effective therapeutics for treatment of moderate to severe pain. However, their use is limited by serious side effects - tolerance, constipation, respiratory depression, physical dependence and high addictive potential. The frequency of clinical pain, coupled with a lack of alternative therapeutic options has led to a nat ...

The goal of this NIH Phase I SBIR proposal is to develop and validate a new method to monitor the symptomatic toxicities and health related quality of life of cancer patients who are undergoing and have undergone radiation therapy during the course of their treatmentThe proposal is built around expertise in mobile application developmentVivonics Incand radiation oncologyDrTJ Fitzgerald of the Univ ...

Current access to and analysis of the Fatal Analysis Reporting System (FARS) dataset requires significant time and technical skill. Data analysis tools are often general-purpose, designed to support the analysis of any dataset, and do not easily support the types of questions many transportation and safety engineers ask of the FARS data. Visualizations can help users understand relationships betwe ...

The project team will develop the EdMod platform for special education practitioners to enter and track information specific to IEPs, such as diagnosis classification, goals, and data collection of those goals. The platform will then generate research-based strategies for teachers to support students with or at risk for disabilities during classroom instruction or in testing. The platform will pre ...

In this project, the team will develop a performance-based lab for the high school level. The Inq-ITS Performance Based Labs for High School Physics and Physical Science will integrate "using mathematics" practices with other science practices to study physics/physical science phenomena. An accompanying teacher dashboard will generate immediate, diagnostic, and actionable alerts driven by algorith ...

In Phase II, ZKxKZ designed, developed and demonstrated an approach for fabrication and rapid installation of low cost modular mini-roundabouts made from recycled plastic boards. Phase II culminated in the installation of one full modular mini-roundabout in both Georgia and Virginia. In addition, 3 modular mini-roundabouts were commercially sold and installed in Canada prior to the SBIR funded sit ...

Knowledge Based Systems, Inc. (KBSI) is pleased to propose the further design and development of MySidewalk mobile application facilitating the crowd-sourced collection of sidewalk inventory and condition data. The MySidewalk application utilizes advances in social networks and data mining to provide integrated sidewalk datasets. Phase I and II research was facilitated by inputs from City of Colle ...

Cardiovascular toxicityCVTxis a serious short and long term complication of many anti cancer chemotherapeutic regimensZamoranoLancellotti et alIn this PhaseSBIR submission to continue the development and validation of Accel Diagnosticsminimally invasiverapidcost effective and connected blood testthe pScreen CVTx TMfor the early detection and continuous of chemotheropy induced CVTx

The goal of the project is to develop a device for percutaneous closure of postinfarction ventricular septal defectVSDin adultsFirst a prototype would be developed and tested in animalsand ultimately a clinical grade device would undergo regulatory developmentPhase I will include the development and testing of a postinfarction VSD occluder prototypePhase II will include mechanical and safety testi ...

Needle access to deep organs is common to numerous catheterradiologicaland surgical proceduresboth diagnostic and therapeuticincluding access to blood vesselspericardial and cardiac chambersvisceraetcMRI operation affords exquisite imaging and delineation of soft tissue beyond what is afforded by X ray fluoroscopyCTand ultrasound guidancePassiveneedles visualized solely by their material propertie ...