Award Data

The major challenge in constellation-wide deployment of tactical payloads in low-Earth orbit (LEO) lies in achieving the performance requirements that are imposed by constellation dynamics while maintaining a design simplicity that is compatible with large-scale production, along with typical constraints on size, mass, and power consumption. Cesium’s proposed solution is a small reconfigurable p ...

Project Summary AbstractThe physiological effect of autoantibody binding to the motor endplate junction nicotinic acetylcholine receptorsAchRcauses numerous symptoms associated with Myasthenia GravisMGand is characterized by drooping of one or both eyesblurred or double visionchange in facial expressiondifficulty swallowingshortness of breathimpaired speech and weakness of muscle functionIn some c ...

The broader impact/commercial potential of this project include the ability to meet the requirements of cable infrastructure while opening additional markets in spectrum allocation by solving key technical problems. There is a massive need for improved connectivity for both fixed and mobile applications, in both urban and rural communities, within the nation. Wired infrastructure has struggled to ...

The broader impact/commercial impact of this proposal is to reduce fraud in telecommunications. Americans received approximately 26 billion so-called "robocalls" last year, and in March 2019, a new monthly record of 5 billion robocalls was reached, according to the FCC. The Federal Trade Commission (FTC) reports the agency is on pace to receive 5+ million complaints about robocalls in 2019, a 30% ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will result from improving the quality of healthcare in the United States and reducing the associated costs for common elective surgery procedures through evidence-driven patient-physician matching. This technology will improve the quality of care and reduce the variation in costs associated w ...

The broader impact & commercial potential of this Small Business Innovation Research (SBIR) project is the ability to control zebra & quagga mussel infestations with a cost-effective and target-specific biological treatment. In addition to the estimated $7 billion economic impact, mussel infestation causes substantial ecological impacts. Currently, there is no treatment option available following ...

The broader impact of this Small Business Innovation Research (SBIR) Phase II project safeguards domestic food supply by improving honeybee health. Honeybees pollinate 1/3 of domestic food supply and contribute more than $15 billion to the U.S. economy. Although honeybee populations are at a 20-year high in the U.S., the cost to keep them alive is at its historical peak. This project reduces labor ...

PROJECT SUMMARY ABSTRACT The performance of many x ray imaging systems is limited by the lack of x ray detectors with simultaneous high quantum efficiency and high spatial resolutionAs examplesdigital mammography scanners typically have a resolution ofm for high quantum efficiencywhich is not sufficient to effectively detect small but critical microcalcificationsX ray micro CT scanners either use ...

Vulnerabilities in telecommunications channels are being exploited at alarming rates by malicious attackers to commit fraud, perpetrate scams, and organize data breaches. In addition to financial losses incurred by corporations and taxpayers, attacks against government agencies such as the DHS can severely compromise national security. A common element of these attacks is the attacker's ability to ...

Abstract The goal of this project is to develop an optimized MNK inhibitor for neuropathic pain treatment. MNK is a kinase that phosphorylates eIF4E to control the translation of a distinct subset of mRNAs. Our focus on this target for neuropathic pain is grounded in evidence that MNK-eIF4E signaling is activated in nociceptors upon exposure to pain promoting cytokines and growth factors as well a ...