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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 3957 results
  1. Clonal Hematopoietic Progenitor Cell Assay

    SBC: Aastrom Biosciences, Inc.            Topic: n/a

    Hematopoiesis, the regulated production of mature blood cells, is a complex scheme of multilineage differentiation which occurs mainly in the bone marrow of adult mammals. Mature cells are continuously produced from progenitor (or precursor) cells. Consequently, assays which detect these progenitor cells are vital in many research and clinical settings. The current assay procedures suffer from a n ...

    SBIR Phase I 1993 Department of Health and Human Services
  2. Hematopoietic Cell Expansion System

    SBC: Aastrom Biosciences, Inc.            Topic: n/a

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  3. Improved Ultrafilters for Bioprocessing

    SBC: Abel Company            Topic: n/a

    Efficient separation and purification of bioproducts on a commercial scale are controlling steps in the bioprocessing of high value-added products such as therapeutics in human health care. This project will examine the feasibility of achieving significant improvement in downstream processing through-put by the use of flow-induced vortices to reduce or eliminate the effect of concentration polariz ...

    SBIR Phase I 1993 Department of Health and Human Services
  4. LASER-ELECTRODE CATHETER FOR AV NODE-HIS BUNDLE ABLATION

    SBC: Abela Laser Systems            Topic: n/a

    ABELA LASER SYSTEMS (ALS) PLANS TO DESIGN, DEVELOP, AND CHARACTERIZE A COMBINATION LASER-ELECTRODE CATHETER FOR PERCUTANEOUS TRANSVENOUS HIS BUNDLE ABLATION. THE CATHETER WILL BE CAPABLE OF SAFELY PROJECTING A SUFFICIENT AMOUNT OF LASER ENERGY TO THE AV NODE-HIS BUNDLE TO ABLATE OR PERMANENTLY MODIFY THE CONDUCTION CHARACTERISTICS OF THAT TISSUE. THIS SYSTEM WOULD FIND IMMEDIATE APPLICATION FOR TH ...

    SBIR Phase II 1993 Department of Health and Human Services
  5. NEW FLOW CYTOMETRY TECHNOLOGIES FOR CLINICAL HEMATOLOGY

    SBC: ABIOMED, INC.            Topic: n/a

    AUTOMATED BLOOD CELL ANALYSIS IS A ROUTINE FUNCTION IN THE CLINICAL HEMATOLOGY LABORATORY. HOWEVER, THE FLOW CYTOMETRIC INSTRUMENTATION PERFORMING THESE TESTS MAY HAVE FUNDAMENTAL LIMITATIONS REGARDING MEASUREMENT OF RED BLOOD CELL VOLUME, RED BLOOD CELL HEMOGLOBIN CONCENTRATION, AND ACCURATE CLASSIFICATION OF WHITE BLOOD CELL SUBPOPULATIONS. THE "HIGH-END" INSTRUMENTS HAVE BECOME VERY COMPLEX AND ...

    SBIR Phase II 1993 Department of Health and Human Services
  6. MINIATURE IMPLANTABLE TRANSCUTANEOUS OPTICAL DATA LINK

    SBC: ABIOMED, INC.            Topic: n/a

    BETWEEN COCHLEAR IMPLANTS AND QUADRI/PARAPLEGICS, THERE ARE APPROXIMATELY 700,000 PERSONS IN THE U. S. WHO WOULD BENEFIT FROM PROSTHETICS UTILIZING NEURAL OR NEUROMUSCULAR STIMULATION. SUCH SYSTEMS REQUIRE IMPLANTABLE, HIGH-SPEED, BI-DIRECTIONAL, TRANSCUTANEOUS DATA TRANSMISSION IMMUNE TO VARIATIONS IN THE LOCAL ENVIRONMENT. TO DATE, DATA LINKS INDEVELOPMENT ARE NOT PROJECTED TO MEET THE COMBINED ...

    SBIR Phase II 1993 Department of Health and Human Services
  7. Disposable High Resolution Falloposcope

    SBC: ABIOMED, INC.            Topic: n/a

    Endoscopic exploration of the utero-fallopian region is useful and may become a more general observational modality if a viewing instrument can be build with a front end that is disposable and inexpensive, has a small diameter with potential for transcervical introduction without anesthesia, and can provide high image resolution. The goal is the development of a falloposcope with high resolution i ...

    SBIR Phase I 1993 Department of Health and Human Services
  8. Optical Periodontal Probe

    SBC: ABIOMED, INC.            Topic: n/a

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  9. Tubular Pediatric Ventricular Assist Device

    SBC: ABIOMED, INC.            Topic: n/a

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  10. Field Localization Of Brain Generators

    SBC: ABRATECH CORPORATION            Topic: n/a

    Preliminary studies have demonstrated the feasibility of a novel computational scheme which will address critical errors in the present methodology of source localization. These studies will also make it feasible to obtain source location and pattern of activity based on realistic models of the head constructed from MRI or CT imaging modalities. Potential clinical applications include functional i ...

    SBIR Phase I 1993 Department of Health and Human Services

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