Award Data

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While auditory evoked responses are often used for objective assessment of hearing, especiallyin infants, such responses do not provide an adequate measure of low-frequency hearing. This, in turn,makes more difficult the selection of a hearing aid appropriate for the patient's hearing deficit.Evaluation of the auditory evoked response is especially difficult because of the brain's response totrans ...

This project is intended to provide computational resources to users of Dipole Source Localization(DSL) methods to allow them to decide whether or not their DSL results are distorted by certain errorscalled model misspecification errors. These errors are essentially due to incorrect weighing constantsin the computation of the relationship between source dipole parameters and the surface potential. ...

We will develop a comprehensive, flexible laboratory software system that controls stimuli anddata acquisition in NIH health-related research studies, to meet the needs of research in cognitivepsychology and neurobiology, in terms of both capabilities and convenience. The Phase I workplan ispart of the overall goal, and is to initially develop the software necessary to present full screen graphics ...

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High-risk newborn infants in an intensive care unit often suffer significant morbidity and mortalitybecause of infectious illnesses which elude early diagnosis and are present in advanced stages withcirculatory shock. Earlier diagnosis and therapy might present in advanced stages with circulatoryshock. Earlier diagnosis and therapy might prevent or reduce late complications and deaths. A strategyf ...

We will extend recent observations regarding the discovery and characterization of alloreaction-a-ssociated antigen (ARAg), a novel member of the immunoglobulin gene superfamily selectively expressedon leukocyte subsets. ARAg surface expression is increased on T lymphocytes in response to allogeneic,but not by mitogenic, stimuli and anti-ARAg monoclonal antibody (mAb) P1C5 specifically blocks this ...

We will develop a new fiber sensor technology based on detection of SP oscillations with thespecific goal of designing a simple, low-cost, remote optical probe capable of measuring HIV and otherviral antibodies upon direct contact with a suitable biological fluid. The sensor will be capable ofdetecting a specific immunological reaction between proteins immobilized onto the fiber sensor and theirco ...

We will create a novel fiber-optic technique to detect the presence and monitor levels ofenvironmentally harmful gases emitted by utility companies and chemical industries as well as presentin inhabited places. Gas molecules are absorbed into a thin film whose optical properties are thenmonitored by surface plasmon spectroscopy. The advantage of this technique over the piezoelectricsensor includes ...

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