Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral Malaria

    SBC: Visionquest Biomedical LLC            Topic: NIAID

    DESCRIPTION provided by applicant VisionQuest Biomedical and its collaborators have assembled a team of inter disciplinary scientists with considerable experience in automated retinal image analysis clinical ophthalmology with specialized research in malarial retinopathy MR and cerebral malaria diagnosis CM This team will develop and test an automated MR screening software system integra ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Novel S. aureus Antibiotics with Reduced Resistance Susceptibility

    SBC: NOVALEX THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Widespread antibiotic use has accelerated S aureus resistance to almost all marketed antibiotic classes including beta lactams fluoroquinolones macrolides aminoglycosides tetracyclines as well as the newer linezolid and daptomycin Methicillin resistant S aureus MRSA is an increasing public health threat with deaths from MRSA infections already compar ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Development of broad spectrum Hepatitis C Virus NS3/4A protease inhibitors

    SBC: NOVALEX THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant This is a collaborative proposal to develop inhibitors with reduced susceptibility to resistance and improved genotype spectrum of activity against the NS A protease of the Hepatitis C virus HCV Over three percent of the worldandapos s population is infected with the hepatitis C virus HCV Unfortunately the current best treatment is still quite challeng ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Software to study brain function during behavior using laser-scanning microscopy

    SBC: Vidrio Technologies, LLC            Topic: 105

    DESCRIPTION provided by applicant Two photon laser scanning microscopy TPLSM is a critical tool for basic and biomedical neurobiology It uniquely allows three dimensional imaging deep within intact brain tissue and at high resolutions TPLSM in vivo has enabled ground breaking studies of normal brain function and disorders of the brain including stroke traumatic brain injury epilepsy Alz ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Rabbit InMAD Discovery of Novel Biomarkers for POC Tuberculosis Diagnostic Assay

    SBC: Immuno-mycologics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB is a chronic infectious disease that infects approximately one third of the worldandapos s population Eighty five percent of the estimated million new cases of TB in occurred in resource limited countries located in Asia and Africa In there were million deaths from TB among HIV negative patients and additional TB d ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Materials Ontology Design and Development (MODD)

    SBC: DECISIVE ANALYTICS CORPORATION            Topic: OSD13C02

    Semantically Linked Data is widely seen as a revolutionary approach for maximizing the usefulness of existing and future information. In the materials domain, semantically linked materials data holds considerable promise with the ability to facilitate materials research and product development, improve communication, and open up avenues for new types of materials informatics. But realizing the pro ...

    SBIR Phase I 2014 Department of DefenseOffice of the Secretary of Defense
  7. Advanced Verification Toolset for Learning-Based UAS Operating in Uncertain Environments

    SBC: AURORA FLIGHT SCIENCES CORPORATION            Topic: OSD13HS2

    This effort proposes to develop a toolset to evaluate the effectiveness of a safety-controller that monitors a learning-based autonomous control system. The traditional use of deterministic verification techniques for real-time monitoring is not feasible in the presence of uncertainty. This effort would advance the recommended verification techniques to include non-deterministic approaches. The ...

    SBIR Phase I 2014 Department of DefenseOffice of the Secretary of Defense
  8. Combined Approaches for Verification and Validation of Run Time Protected Systems

    SBC: BARRON ASSOCIATES, INC.            Topic: OSD13HS2

    Barron Associates has assembled a team of researchers that include Dr. Sayan Mitra of the University of Illinois and Dr. Ufuk Topcu of the University of Pennsylvania. They will spearhead three complimentary investigations into the development of verification and validation (V & V) approaches for adaptive systems protected by run time assurance (RTA) mechanisms. Two of these approaches involve us ...

    SBIR Phase I 2014 Department of DefenseOffice of the Secretary of Defense
  9. Direct Injection Systems for Improved Performance, Durability, and Economy

    SBC: KINETIC BEI LLC            Topic: OSD13PR1

    Kinetic BEI, LLC. proposes a dual path approach to fulfilling the need for a direct injected heavy fuel delivery system for engines under 200 Hp. The primary focus will be to advance the Miniature CI Fuel Injection System, a system whose individual components have been demonstrated in on-engine testing in a laboratory environment. The new system will integrate the next generation Miniature CI In ...

    SBIR Phase I 2014 Department of DefenseOffice of the Secretary of Defense
  10. A Design Automation Tool for Integrated Nanophotonics based on Compact Modeling and Model Order Reduction

    SBC: CFD Research Corporation            Topic: OSD13C05

    Existing physics-based device simulation tools are prohibitively expensive computationally, and therefore ill-suited for parametric analysis and design optimization of photonic integrated circuits (PIC). The proposed effort aims to develop and demonstrate an innovative, easy-to-use simulation tool for accurate, fast circuit/system analysis of PICs. The salient aspects of the proposed solution are: ...

    SBIR Phase I 2014 Department of DefenseOffice of the Secretary of Defense
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