Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development of Middle School and High School STEM Programs in ITS and CV Technologies

    SBC: Nanosonic Inc.            Topic: 141FH4

    NanoSonic will work with the Giles County, Virginia,school system,and Leidos, a developer of ITS NanoSonic will work with the Giles County, Virginia,school system,and Leidos,a developer of ITS and CV technologies,to create and deliver a set of STEM lesson plans involving ITS and CV concepts. With Leidos transportation engineers, NanoSonic will identify project ideas,and with Giles County STEM teac ...

    SBIR Phase I 2014 Department of Transportation
  2. In-situ Sensors for Cathodic Protection Interrelationships Modeling

    SBC: SENCONTROLOGY, INC.            Topic: 132PH2

    To adequately protect underground pipelines, a coating (including polyurethane foams) must conduct CP current when disbondment occurs. The realization of a reliable, multi-functional process/material system that can ensure urethane foams not only perform in harmony with CP, but establishing the worthiness of their continued use would be of major benefit to the national transportation system. Senc ...

    SBIR Phase I 2014 Department of Transportation
  3. The eSparkBeat: A Pulse on the Modern Classroom

    SBC: ESPARK LEARNING            Topic: N/A

    eSpark is a website that provides teachers curated playlists of tablet-based apps, videos, and assessments tailored to students’ individualized learning needs. In this project, the research team is developing a prototype of eSparkBeat, a dynamic dashboard to provide teachers useful content and resources tailored to particular classroom foci to improve instruction. The intended users of eSpark wi ...

    SBIR Phase I 2014 Department of Education
  4. Endotoxin Neutralization as a Biomonitor for HIV Disease Progression

    SBC: BIODTECH, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Endotoxin neutralization in human plasma is an excellent indicator of chronic immune activation, which is the most accurate predictor of mortality in HIV. Recently we developed an assay using endotoxin neutralization asan indicator of bacterial translocation. This assay is accurate in discriminating control patients from those with inflammatory bowel disease in ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Preclinical Studies of PG70 LEAPS Peptide Vaccines for Rheumatoid Arthritis

    SBC: CEL-SCI CORPORATION            Topic: NIAMS

    DESCRIPTION (provided by applicant): Currently, FDA-licensed pharmaceuticals used to treat rheumatoid arthritis (RA) focus largely on alleviation of symptoms, either through pain management, general immunosuppression, or by antagonizing cytokines such as TNF-?. Despite recent advances in biologic therapies, these treatments do not address the underlying autoimmune condition. Ligand epitope antigen ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Topically-delivered Mutation-specific Gene Targeting for Epidermolytic Ichthyosis

    SBC: Exicure, Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): AuraSense Therapeutics (AST), along with Northwestern University, is applying a recently developed technology using oligonucleotide-functionalized nanoparticles (called spherical nucleic acids or SNAs) to control protein expression. These easily synthesized nanoparticles can have either DNA or RNA shells, and are less than 50 nm in hydrodynamic diameter. SNA co ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Assessment of Hypercoagulability in Cancer Patients Using Sonorheometry

    SBC: HEMOSONICS            Topic: NCI

    DESCRIPTION (provided by applicant): The Problem: Venous thromboembolism (VTE), which encompasses the diseases of deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and life-threatening problem amongst cancer patients. In population-basedstudies, cancer has been associated with a 4-fold increase risk for VTE; in cancer patients undergoing systemic chemotherapy treatment the risk i ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. New High Throughput Anti-Tumor Drug Screening System

    SBC: Vivo Biosciences Inc            Topic: NCI

    DESCRIPTION (provided by applicant): This SBIR project is focused to develop, validate and commercialize an advanced high-throughput anti- tumor drug screening platform (HTS) which employs a new 3D HuBioGEM assay technology. Preclinical drug screening is commonly performed using biochemical and cell-based assay systems. In recent years, more relevant 3D spheroid models have been developed using mi ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Development of a new anti-inflammatory peptide for treatment of type II diabetes

    SBC: SERPIN PHARMA, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type II diabetes (T2DM) affects more than 5% of the population in Western countries. In the US alone, about 23.6M children and adults have diabetes, and the associated cost was estimated to 174 billion in 2007. The rise in T2DM prevalence is linked to the dramatically increased incidence of obesity, which now affects about a third of the adult US population. H ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Chronically Acting CFTR Inhibitor Discovery for Secretory Diarrhea and ADPKD

    SBC: DISCOVERYBIOMED, INC.            Topic: NIDDK

    Project Summary Abstract DiscoveryBioMed, Inc. (DBM) has launched an innovative and automation-friendly drug discovery program to screen a collection of small molecular compounds on a human epithelial cell platform expressing physiologically relevant levels of the wild-type Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) to discover a new class of therapeutic drugs for secretory disease ...

    SBIR Phase I 2014 Department of Health and Human Services
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