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Frog Embryo Teratogenesis Assay: Xenopus (FETAX) is a 96-h, whole-embryo bioassay designed to detect potential developmental toxicants. The primary goal of this research is to improve the predictability and increase the overall utility of FETAX as a screen for developmental toxicants that pose a hazard to human health. Since Xenopus laevis embryos lack mixed-fliriction oxidase metabolism (cytoch ...

IA, Inc. proposes to develop a light weight, field-portable, fiber-optic sensor capable of measuring a panel of prognostic and diagnostic infection indicators including IL-6, TNF-alpha, IL-12, and CRP. The proposed sensor will provide a system suitable for field medical units which is capable of early detection of infection, and will require only minimally trained operators. The sensor will be a ...

Natural materials such as tooth, bone or shell consist of a high volume fraction of ceramic grains coated by thin layers of proteinaceous film. The ceramic grains are grown in situ in a pre-formed organic polymer matrix. The organic portion provides high toughness, while the ceramic component provides stiffness. This unique microstructure allows for mechanical properties superior to man-made ce ...

Eye tracking and voice recognition provides a means for hands-free control of information displayed within a head-mounted display (HMD) device. This proposal outlines a program for combining eye tracking, voice recognition, and HMD technology to achieve an integrated hands-free soldier interface. With this device the soldier can quickly adapt displayed information to meet changing needs of the t ...

M-Vision Inc., along with the University of Michigan and Michigan State University, proposes to develop a new and novel solution to the problem of target detection and discrimination in a complex scene. This solution is obtained by innovatively combining Gabor wavelets and scale space inference. The result is a computational model of human perception that resembles the human visual system in its ...

Tactical wheeled vehicles represent a prominent portion of the Army's budget for both acquisition and operating costs. TACOM has identified suspension lubrication as a mission critical area for improvement. The goal is to lubricate a vehicle's suspension continuously for two years. This should create a cascade of cost effects in both maintainability and reliability. Single-point lubricators ba ...

Two small businesses, ThermoAnalytics (prime contractor) and Aerodyne Research (subcontractor) , propose to collaborate on a major integration of signature codes. Government agencies have been sponsoring independent signature code development programs for several years resulting in very specialized analysis tools. This proposed effort will directly support the integration of the PRISM/MuSES, SPI ...

This research project is directed at developing advanced, high-performance, operator-machine interfaces that can be applied to a wide range of real military and commercial applications. As a first step in this direction, we are proposing to collect interface performance data and use this data to develop, implement, and evaluate concept approaches for advanced soldier computer interface systems. ...

The ability of either a human observer or an automated sensor to recognize a target in an infrared scene depends both on the target and clutter content of the infrared scene. Metrics have been developed to quantify the difference between the target and its background, to be used as independent variables in the modeling of both observer performance and of automated seeker performance. We believe ...