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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 4495 results
  1. IGF::OT::IGF SBIR TOPIC 379: DIGIBIOMARC: DIGITAL BIOMARKERS FOR CLINICAL IMPACT- MOONSHOT PROJECT(FAST TRACK)

    SBC: Medable Inc.            Topic: NCI

    The overall objective of this Fast Track SBIR contract project is to develop DigiBioMarCTMDigital BioMarkers for Clinical Impacta scalable and flexible cloud based platform to capture and analyze wearableimplantableor external device dataThis platform also provides an informatics tool for automated data aggregationintegrationand machine learning algorithmsIt is based on the scalable user centered ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. NOVO-118 as a therapeutic to promote remyelination in in vivo models of MS

    SBC: NOVORON BIOSCIENCE INC            Topic: NINDS

    7. Project Summary Multiple sclerosis (MS) is a neurodegenerative disease in which myelin of the central nervous system (CNS) is destroyed by a self-reactive immune response. This demyelination is accompanied by the death of the myelinating cells themselves, the oligodendrocytes. Repeated bouts of demyelination leave the denuded CNS neurons vulnerable to degradation and is the major cause of neuro ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Head-mounted miniature microscopes for combined calcium imaging and electrophysiological measurement of neural circuit function in deep brain regions of behaving macaques

    SBC: Inscopix, Inc.            Topic: 101

    PROJECT SUMMARY A consensus has emerged in the Neurosciences over the last decade regarding the critical importance of understanding brain function at the level of neural circuits. Such an understanding can help us bridge across scales of investigation to provide a more comprehensive model of brain function, while also providing a more direct link to the dysfunctions associated with neurological d ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Novel monoclonal antibody for single dose treatment of acute CNS injury

    SBC: Oncosynergy, Inc.            Topic: 999

    PROJECT SUMMARY Traumatic brain injury (TBI) represents a significant societal and economic impact. To date, there are no FDA- approved pharmacotherapies to prevent or reverse TBI. The standard of care in an emergency setting focuses first on stabilizing the patient and secondly on management of cerebral hemodynamics. The patient may undergo surgery to remove hematomas, repair skull fractures, and ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Software Development--Drug Abuse Ethnographic Research

    SBC: Applied Sciences Research            Topic: N/A

    Since the mid-1970's, information on current and emerging drug abuse patterns and trends has been bepidemiologic data derived primarily from national probability samples and population-based surveys.however, there has been increasing interest in use of data generated through ethnographic methods toof drug abusing behavior. While surveys typically answer questions about the nature and extent of drt ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. Targeting lipid rafts for treatment of migraine

    SBC: RAFT PHARMACEUTICALS LLC            Topic: NINDS

    PROJECT SUMMARY Migraine is a highly prevalent condition with an extraordinarily negative impact on quality of life and represents a heavy socioeconomic burden to the societyprimarily because of decreased working efficiency and workdays lostManagement of migraine has become increasingly pharmacological during recent yearsWhile several therapeutic options existmost of the prophylactic drugs current ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Pre-clinical evaluation of DT-001, a small molecule antagonist of MD2-TLR4 for utility in the treatment of pain.

    SBC: Douleur Therapeutics Inc            Topic: NINDS

    Project Summary AbstractUpwards ofmillion individuals are afflicted by chronic pain in the US alonewithmillion of these individuals suffering from neuropathic painOn a global scalechronic pain affectsbillion individualswithwho endure lower back painFrom a clinical perspectivethe International Association for the Study of Pain approximates thatinpatients present with painand on an annual basisinpat ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development of An Oral,Brain/Eye penetrating, Second Generation TTR Stabilizer for The Treatment of Transthyretin Amyloidoses

    SBC: PROTEGO BIOPHARMA, INC.            Topic: NINDS

    The TTR Amyloidoses (ATTR) are rare, progressive, ultimately fatal diseases that compromise the function of multiple organs, causing a wide range of debilitating clinical symptoms. ATTR is caused by the dissociation of the tetrameric transthyretin (TTR) protein, leading to misfolding and aggregation of the released monomers with toxic oligomer formation and subsequent tissue deposition as physiolo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Supplement to Promote Diversity and Inclusion, Female Scientist

    SBC: NAVEGA THERAPEUTICS, INC.            Topic: NINDS

    Project Summary/Abstract Currently more than 100 million Americans and 1.5 billion people worldwide suffer from chronic pain. This is more than cancer, diabetes, and heart disease combined. Voltage-gated sodium channels are responsible for the transmission of pain signals. Nine genes have been identified, each having unique properties and tissue distribution patterns. Genetic studies have correlat ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. An urgently needed low-cost, rapidly deployable platform for simultaneous SARS-CoV-2 viral particle and COVID-19 IgG/IgM detection and quantification

    SBC: Nodexus Inc            Topic: NCI

    By adapting low-cost technology developed by Nodexus prior to and during the course of the current NCI Phase I SBIR award, we hereby propose a low-cost, rapidly deployable platform for quantification of both SARS-CoV-2 viral particles and anti-SARS-CoV-2 IgG/IgM antibodies simultaneously from saliva by bead-based capture in a simple flow-through assay for low-infrastructure screening utilizing pat ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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