Award Data

Adenosine produces coronary vasodilation through activation of A-2a adenosine receptors. However adalso acts at A1 adenosine receptors to slow atrioventricular conduction and when injected into man ican be blocked with A1 receptor antagonists. DTI has synthesized a number of adenosine analogs that2a subtype of adenosine receptor and have identified WRC-0470 as a potent selective short acting corou ...

CLINICAL INFORMATION SYSTEMS ARE THE WEAKEST COMPONENT OF SOFTWARE PACKAGES AVAILABLE TO HOME HEALTH AGENCIES. THE GOAL OF THIS PROGRAM IS TO DEVELOP A MODULAR CLINICAL INFORMATION SYSTEM FOR THE COLLECTION, USE, AND REPORTING OF HOME HEALTH PATIENT INFORMATION WITH A UNIVERSAL INTERFACE TO CURRENTLY AVAILABLE HOME HEALTH INFORMATION SYSTEMS. THE POINT OF CARE DATA ENTRY TOOL WILL BE ELECTRONIC SL ...

A DOT IMMUNOASSAY FOR THE DETECTION OF ACROSOME REACTION OF HUMAN SPERM WILL BE DEVELOPED FOR USE IN THE DETECTION OF MALE INFERTILITY. SCREENING TESTS FOR THE DETERMINATION OF THE CAUSES OF INFERTILITY AND SCREENING SEMEN SAMPLES FOR SPERM BANKING HAVE BECOME MAJOR RESPONSIBILITIES OF FERTILITY CLINICS. HOWEVER, NO SIMPLE METHOD CURRENTLY EXISTS FOR THE DETERMINATION OF THE FUNCTIONAL ABILITY OF ...

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DESCRIPTION (provided by applicant): This project will determine the performance and operating specifications for a low-cost optical ammonia sensor for medical applications. Ammonia in human breath has been established as a significant biomarker with high potential for treating kidney and liver diseases as well as detection of bacterial infections. Widespread application of breath tests is curren ...

This project is to design develop and test a culturally sensitive computer- interactive program forstyle, health, and dietary practices of African American women. The "Afro-SISTER" Program is the acrAfro-Sensitive Information System To Evaluate Risk" (SISTER) of nutrition-related diseases. The progprompted on a touch-sensitive computer screen. It will display culturally relevant activities, ethnil ...

THIS RESEARCH WILL DETERMINE THE FEASIBILITY OF DEVELOPING AND MARKETING AN OLDER-WORKER PRODUCTIVITY APPRAISAL TRAINING SYSTEM FOR PERSONNEL AND HUMAN RESOURCE DEPARTMENTSIN BUSINESS AND INDUSTRY. PHASE I RESEARCH IS BASED ON THE HYPOTHESIS THAT THERE IS AGE-RELATED BIAS IN THE SUPERVISORYRATINGS OF OLDER EMPLOYEES THAT NEGATIVELY IMPACTS THE PRODUCTIVITY ESTIMATES OF OLDER EMPLOYEES. THE SYSTEM ...

DESCRIPTION (provided by applicant): Clinical dilemma: Recent advances in biologic therapies for rheumatic diseases provide a means for more profound disease management. Proper diagnosis is a necessary aspect of choosing the proper biologic therapy. While disease diagnosis, based on clinical findings and laboratory tests, is effective in a significant number of patients, it can be problematic in ...

DESCRIPTION (provided by applicant): Brain accumulation of amyloid-2 (A2) and chronic brain inflammation are both recognized factors in the pathophysiology of Alzheimer's disease (AD). Brain inflammation primarily involves microglial cells. The neural toxi city of A2 is microglia-mediated and involves signaling through transcription factor NF:B. Limiting the activation of NF:B in microglia may be ...