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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biomimetic Control of Flying Robots

    SBC: PHYSICAL SCIENCES INC.            Topic: A08056

    Physical Sciences Inc. (PSI) demonstrated in Phase I that it is possible to design a Micro Air Vehicle (MAV) which is robust to collisions by using techniques similar to what insects use to recover from collisions while still in flight. Observational studies of insects colliding with objects (high speed films of instrumented insects) conducted at the Harvard Microrobotics Laboratory show that the ...

    SBIR Phase II 2010 Department of DefenseArmy
  2. Preclinical development of a novel antibacterial for Clostridium difficile diseas

    SBC: GLSynthesis Inc.            Topic: NIAID

    ABSTRACT Among inhibitors of Gram+ DNA polymerases IIIC and IIIE, several compounds are active against multiple strains of the anaerobic Gram+ bacterium Clostridium difficile (Cdiff). The compounds appear to be selective for Cdiff compared with other Gram+ anaerobes and aerobes, and a lead compound - 2-(3,4-dichlorobenzyl)- 7-(5-morpholinylpentyl)guanine or 359E - is active orally in protecting h ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid point of care test for Lyme serodiagnosis based on novel ultra sensitive de

    SBC: IMMUNETICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Lyme disease is the most prevalent vector borne disease in the U S with about cases per year reported by CDC and a range now covering states Early diagnosis and treatment of Lyme disease is important to prevent the disease from progressing to a systemic infection characterized by chronic arthritis carditis or neurological disorders Where a patien ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. "LAPPD Commercialization Fully Integrated Sealed Detector Devices

    SBC: INCOM, INC.            Topic: 38a

    The high energy physics (HEP) community, the scientific and medical communities and the public at large, require the availability of high sensitivity photo- sensors with improved spatial and temporal resolution that can be scaled to large areas, and manufactured in a robust, durable, and compact package at a low cost. Phase I successfully demonstrated the underlying enabling scientific and techni ...

    SBIR Phase II 2014 Department of Energy
  5. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Globally, an estimated 16.2% of the human population is infected with HSV-2 including gt17% of the U.S. adult population. Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV-2infection can cause neonatal herpes with high infant mortality. HSV-2 infection in the adult population has increased substantially in the past ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: R

    DESCRIPTION provided by applicant Globally an estimated of the human population is infected with HSV including andgt of the U S adult population Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV infection can cause neonatal herpes with high infant mortality HSV infection in the adult population has increased substantially in the ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Expression-Based Multi-Gene Signatures for CRC Recurrence and Chemoselection

    SBC: AMBERGEN, INC            Topic: NCI

    DESCRIPTION (provided by applicant): Colorectal cancer (CRC) is the second leading cause of cancer deaths in the U.S and Western world. Despite increased screening and advances in treatment, the mortality rate (~50,000/year) and high national health-care burden for CRC is likely to remain high unless more effective methods are developed to predict recurrence and response to chemo-radiation ther ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Isolating novel fungi for antibiotic discovery

    SBC: NOVOBIOTIC PHARMACEUTICALS, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to discover and develop novel broad-spectrum antibiotics acting against critically important human pathogens. The unmet need is especially acute for Gram-negative pathogens, where we are rapidly running out of options for treating multidrug resistant species of Pseudomonas, Acinetobacter, Burkholderia, Klebsiella and Enterobacter. T ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Humanized Antibody Therapeutic to Improve Cardiac Function Following Myocardial I

    SBC: DECIMMUNE THERAPEUTICS, INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary/Abstract Acute myocardial infarction (AMI) affects over 1 million US individuals a year and at the present there are no preventive therapeutics other than direct percutaneous coronary intervention. DecImmune's long-term goal is to develop therapeutics to reduce the severe lethal reperfusion injury that follows removal of coronary artery blo ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Multiplexed Bead-based In Vitro Pediatric Allergy Test

    SBC: AMBERGEN, INC            Topic: NIAID

    DESCRIPTION provided by applicant This proposal focuses on the development of a high throughput high sensitivity low blood volume multiplex assay for in vitro diagnosis of allergies termed AllerBead tm Allergies comprise a group of immune disorders constituting the th leading cause of chronic disease in the US In the case of pediatric allergies over million children ar affected a nu ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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