List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 5658 results
  1. Randomized Prospective Phase II Clinical Trial of NVX in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme GBM is a malignant primary brain tumor affecting about new cases per year in the U S Average survival is only about months Radiation RT is most commonly administered as fractions of Gray each over weeks with concomitant temozolomide TMZ GBM tumors are hypoxic The primary mechanism of RT is creation of singlet oxygen hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Correlating TCR diversity to immune reconstitution after cord blood transplant

    SBC: ADAPTIVE BIOTECHNOLOGIES CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Many patients requiring stem cell transplantation for hematological malignancies are unable to find a suitable HLA matched sibling or unrelated donor Transplants using stem cells from umbilical cord blood provide an alternative for these patients allowing transplantation to proceed with less stringent HLA matching requirements Unfortunately in addition to t ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    Abstract The treatment of large cartilage lesions is a difficult clinical problem for which there are few good solutions Left untreated these lesions tend to degenerate to chronic pain and osteoarthritis OA ultimately requiring a total joint replacement For patients suffering from knee OA and in particular unicompartmental OA unicondylar knee arthroplasty UKA is an available first lin ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Novel therapeutic agent to prevent hearing loss during aminoglycoside therapy

    SBC: ORICULA THERAPEUTICS, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Aminoglycoside antibiotics AGs are important for the treatment of a variety of serious infectious diseases including septicemia complicated intra abdominal infections complicated urinary tract infections and nosocomial respiratory tract infections AGs are the mainstay of treating Pseudomonas infection in patients with cystic fibrosis and one of the best c ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Non invasive Promotion of Clearance of Kidney Stones and Fragments

    SBC: Sonomotion Inc.            Topic: 400

    DESCRIPTION provided by applicant Kidney stones affect in Americans at an annual cost of $ B with both numbers steadily climbing Watchful waiting is the preferred approach to stone management but there are no means to predict when the stone will pass or if the stone will pass Intervention is typically recommended once a stone is over mm and usually involves breaking the stone into s ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTION provided by applicant Microarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugs Typically protein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another device During each testing cycle the entire microarray becomes expos ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Service and Software Solution for the Rigorous Design of Animal Studies

    SBC: SERALOGIX, LLC            Topic: NIDA

    The primary goal of this fast track project is to commercialize a cloud based software suite complemented with on call expert services to guide life science researchers that may have minimal statistical and experimental design ED knowledge to rigorously plan optimize justify manage and report results for complex animal studies Inadequately planned experiments e g lack of randomization b ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. An Ultra filtrate perfusion bio artificial pancreas for high density islet replacement without immunosuppression

    SBC: Cell-Safe Life Sciences LLC            Topic: NIDDK

    DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immun ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. STTR Phase I: Autonomous Landing of sUAS onto Moving Platforms

    SBC: Planck Aerosystems, Inc.            Topic: EW

    The broader impact/commercial potential of this project is the expansion of autonomous unmanned aerial systems (UAS, or drones) to new maritime operational environments and commercial markets. The proposed technology will enable small UAS to operate from vessels moving at sea, without the need for a dedicated pilot or installed hardware, even while far from shore and beyond the reach of establishe ...

    STTR Phase I 2017 National Science Foundation
  10. STTR Phase I: A Low Cost Robotics kit for Elementary Education

    SBC: BirdBrain Technologies LLC            Topic: EA

    This project intends to design and develop a programmable electronics and robotics kit that catalyzes the learning of computational thinking, engineering design, and making at a price point that will be affordable for large numbers of elementary school classrooms throughout the nation. Such an educational robotics kit benefits society by positively influencing science, technology, engineering, and ...

    STTR Phase I 2017 National Science Foundation

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government