Award Data

The Defense Modeling and Simulation Office (DMSO) has developed the High Level Architecture (HLA) as one of the principle components of a DoD-wide Common Technical Framework for modeling and simulation (M&S). Unlike previous distributed simulation technologies such as DIS and SIMNET, HLA provides federation developers, via the Object Model Template (OMT), the means to define the structure and for ...

Sample preparation has been recognized as the single most important challenge to be faced in the development of detect-to-warn (DTW) systems (NRC, 2005). Available commercial sample preparation technologies are expensive, slow (30 min to 2 hours) and require trained laboratory technicians for operation. Addressing this need, we propose to design, fabricate, demonstrate, and validate a novel integr ...

Current bioaerosol monitoring and evaluation systems are largely based on collection of airborne pathogens in a liquid medium, followed by the detection of the targets of interest. While available aerosol collection technologies employ large collection volumes, biosensors are capable of processing only a small fraction of the collection volume. Our overall objective is to design and demonstrate a ...

A new liquid crystal based detector (acousto-optic sensor) will be developed for operation at frequencies below 500kHkz. The superior acoustic detection sensitivity of the sensor will be demonstrated and its feasibility for providing efficient and cost-effective means of acousto-optic image conversion in underwater acoustic imaging systems will be established.

Anti-cancer immunization is limited by the poor immunogenicity of tumor-associated antigens (TAAs) normally used for vaccination. This problem may be overcome by direct adenovirus-mediated delivery of TAAs to dendritic cells (DCs), which play a centralrole in the generation of the immune response. The specificity and efficiency of this vaccination strategy may be improved by specifically targeting ...

Anti-cancer immunization is limited by the poor immunogenicity of tumor-associated antigens (TAAs) normally used for vaccination. This problem may be overcome by direct adenovirus-mediated delivery of TAAs to dendritic cells (DCs), which play a centralrole in the generation of the immune response. The specificity and efficiency of this vaccination strategy may be improved by specifically targeting ...

Care for the wounded Warfighters in austere and remote settings makes medical knowledge, skills and efficiency of the military medical professional paramount. For wounds that extend deep into internal anatomy, proper visualization of internal anatomy can

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

Gun-launched applications currently expose inertial measurement units (IMUs) to harsh acceleration, shock, and vibration environments. Furthermore, as they become smarter, they present tighter constraints on size, weight, power, and cost (SWaP-C), while still requiring high levels of performance. New accelerometer technology must reduce SWaP-C while operating through high-g acceleration environmen ...

Mission times for high velocity projectiles (HVP) are very short and detection and discrimination of targets must happen quickly and decisively. One way to achieve this is through the enhanced contrast resulting from polarized sensing, which tends to highlight manmade objects and suppress natural background clutter. Thermal polarimetric sensing in a small package has been demonstrated already but ...