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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Solid Polymer Electrolytes Derived from Polyphenols

    SBC: TechDrive, Inc.            Topic: N/A

    The objectives are the preparation and evaluation of new solid polymer electrolytes (SPEs), derived from polyphenols, which may be used in the development of improved light-weight solid-state lithium batteries that supply a high number of watt-hours in a small volume. Two types of phenol monomers containing polyether or perfluoroalkyl sulfonic acid segments para to the phenolic function will be ...

    SBIR Phase I 1998 Department of DefenseOffice of the Secretary of Defense
  2. Lightweight, Portable, Blast-Resistant Barrier

    SBC: TENSION SYSTEMS L.L.C.            Topic: N/A

    Tension systems proposes to build lightweight, portable, blast-resistant barriers using tensigritic structures that consist of: an inner and outer fabric or film skin; discontinuous compressive members; connective tensile elements of Vectran cordage; proprietary mechanical connectors to attach the skins, compressive and tensile members; and an anchoring system. The size and shape of barrier proto ...

    SBIR Phase I 1998 Department of DefenseOffice of the Secretary of Defense
  3. TOPIC 386: NOVEL ORALLY BIOAVAILABLE PDE-CATENIN INHIBITOR CONCENTRATES IN LUNG FOR CANCER CHEMOPREVENTION

    SBC: ADT Pharmaceuticals, LLC            Topic: NCI

    This application is based on ADT Pharmaceuticalsdiscoveries thatthe cGMP degrading phosphodiesterase isozymephosphodiesteraseAPDEis overexpressed during early stages of tumorigenesisgenetic knockdown of PDEresults in selective apoptosis of tumor cells by activating cGMP PKG signalingandsmall molecule inhibitors of PDEinduce apoptosis by PKG phosphorylation of oncogeniccateninthereby suppressing Tc ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 384: CANCERCOSTDETOX: DETOXING CANCER CARE FINANCIAL TOXICITY

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The prohibitive cost of cancer care has been widely describedCancer treatment received by patients with insurance can still result in a considerable financial burdenNon adherence is one of the best studied outcomes resulting from higher care costsFinancial distress has also been linked to changes in treatment related decision makingincluding the decision against a treatment course because of costA ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. STING Inhibitor Discovery for Rare and Common Autoimmune Diseases

    SBC: DISCOVERYBIOMED, INC.            Topic: NIAID

    Principal Investigators for Small BusinessDiscoveryBioMedIncDBMand Nitor TherapeuticsIncNitorProject Summary Abstract The over arching commercial goal for this Nitor TherapeuticsIncNitorand DiscoveryBioMedIncDBMcollaboration is to discover and validate Stimulator of Interferon Genes orSTINGinhibitor ligands in a novel high throughput screeningHTSand validation based Critical Path of bioassaysAberr ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Rodents Derived Synthetic Blood Brain Barrier Models for Chemical Toxicity Screening

    SBC: CFD Research Corporation            Topic: NIEHS

    AbstractThe overall goal of this study is to develop and demonstrate a novelpredictive in vitro organotypicD culture models of the blood brain barrierBBBderived from rodents for chemical toxicity screeningIn contrast with current Transwell based static and microfluidic assaysour commercially available SynBBB model enables real time visualization and quantitation of transport permeation under physi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of digital and interactive methods to teach immunology

    SBC: FLUID CONTENT INC            Topic: NIGMS

    Abstract The goal of this project is to develop a digital media based program to teach high school student about immunologyWe will develop an interactive digital media to teach minority studentshigh schoolon the introduction of immunology and compare the efficacy of learning between traditional teaching and interactive mediaWe will develop three curriculums to teach group of high school students r ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Device to Measure Pain using Facial Expression Recognition Integrated with Patient PAINReportIt Tablet

    SBC: ENURSING LLC            Topic: NIDA

    Abstract Our goal is to develop a product that will objectively measure pain using computer vision and machine learning technologies together with tablet based self reported pain data from patients for research or clinical purposesOur device will be low cost because it will consist of one or two cameras to record the video and a computer to analyze the video in almost real timeThe software of the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Amorphous Pharmaceutical Product Development Using Containerless Methods

    SBC: Materials Development, Inc.            Topic: 300

    Amorphous Pharmaceutical Product Development Using Containerless Methods Project Summary The overall objective of this research is to advance drug discovery through precise “engineering” of the structure and properties of API-bearing phases. Many emerging drugs cannot be used in their naturally insoluble crystalline forms or they require crystallization in a preferred polymorph in order to be ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Targeted Small Molecular Mertansine Delivery for Triple Negative Breast Cancer Treatment

    SBC: Iria Pharma, LLC            Topic: 102

    Project Summary Triple negative breast cancerTNBCis a subtype of breast cancerthat occurs in aboutof diagnosed breast cancerswhich is more likely to affect younger peopleAfrican AmericansHispanicsand or those with BRCAgene mutationThe projected TNBC annually diagnosed cases in United States are estimated to be more thanbyDue to the lack of the identified receptors on tumor cell surfaceTNBC patient ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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