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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Direct Performance Evaluation of Additive Manufacturing Process Plans

    SBC: INTACT SOLUTIONS, INC            Topic: None

    Additive manufacturing is steadily advancing towards fulfilling its promise of customized and on-demand production of functional parts. However, performance of as-manufactured parts can differ significantly from the as-designed parts because the as-manufactured geometry differs from the as-designed geometry and the asmanufactured material properties are not known. Attempts to predict performance o ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Take on Training with Attainment: A Universally-Designed Video Training App to Foster Independence at Work for Individuals with Intellectual Disabilities.

    SBC: ATTAINMENT CO., INC.            Topic: NA

    This project develops Take on Training by Attainment, an application (app) that provides comprehensive instruction to job coaches and direct service workers (DSWs) to increase the independence of individuals with disabilities, maximize their independence on the job site, achieve advancement, and promote sustained employment. The goal for Take on Training by Attainment is to research and develop a ...

    SBIR Phase I 2019 Department of Health and Human ServicesAdministration for Community Living
  3. Take on Training with Attainment: A Video Training App to Foster Independence at Work for Individuals with Intellectual Disability

    SBC: ATTAINMENT CO., INC.            Topic: na

    This project researches and develops a mobile application (app), Take on Training, to provide direct services workers (DSWs), including job coaches, with on-demand instruction by way of short vignettes to promote the maximum level of independence for people with disabilities at work. Objectives for this Phase II project are to produce a commercially available, mobile, cross-platform app for job co ...

    SBIR Phase II 2019 Department of Health and Human ServicesAdministration for Community Living
  4. Passive Exoskeleton for Children with Neuromuscular Disorders

    SBC: RUSH RIVER RESEARCH CORP            Topic: NICHD

    Project Summary/Abstract Rush River Research (RRR) Corporation proposes to develop and commercialize a novel passive exoskeleton that helps young children with very little residual strength to use their arms. The proposed orthosis could help the over 500,000 children with many different neuromuscular disorders including muscular dystrophy, spinal muscular atrophy, cerebral palsy, arthrogryposis mu ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Lysis-free extraction of biopharmaceuticals from the periplasm of Clean Genome E. coli

    SBC: SCARAB GENOMICS, LLC            Topic: NIAID

    Thirty percent of recombinant therapeutic proteins are made in Ecoli and include important vaccine components such as carrier proteinsFurtherburgeoning new immunotherapies that use proteins such as single chain antibodies and virus like particles are enjoying increasing successTo meet the production needs of these expanding areasScarab Genomics proposes to extend the versatility of its Clean Genom ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. HLS-Cardiac Safety AI Trained Human Heart and Micro Heart Model

    SBC: Invivosciences, Inc.            Topic: NHLBI

    HLS17-12. The US FDA is considering to establish a new cardiac safety assessment approachdefined by a new paradigm called, “Comprehensive in vitro Proarrhythmia Assay (CIPA)”. The CIPA will 1) assess drug effects on each cardiac ion channel type individually using a high- throughput assay ion channel assays, 2) compute net effect on repolarization and risks fortorsade pointes (TdP) using a mat ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Scalable post-assembly editing software for finishing and annotating personal genomes

    SBC: DNASTAR, INC.            Topic: 300

    We are entering a new era of personal genomics where an individualandapos;s genome sequence will be used to identify disease susceptibility, improve diagnosis and better treat illnesses as well as be combined across cohorts and populations to identify new biomarkers and causal mutations underlying any phenotype. Despite the tremendous success of mapping short read next-generation sequencing (NGS) ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Custom-Fit Personal Sound Amplification Smartphone Application

    SBC: ASCENDING HEARING TECHNOLOGIES, LLC            Topic: NIDCD

    PROJECT SUMMARYPersonal sound amplification productsPSAPshave recently become available to the publicPSAPs serve a potentially important role in providing audibility of sounds for adults who have difficulty hearing in some daily living situationsbut may not be candidates for traditionalhigh amplification hearing aidsFewer thanof adults with hearing loss reporting use of hearing aidsciting high cos ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A novel asthma drug candidate targeting the GABAergic system in lung inflammation

    SBC: PANTHERICS INCORPORATED            Topic: NHLBI

    The proposed research will advance preclinical characterization and validation of a novel drug for asthmaA growing body of research has uncovered functional gamma amino butyric acid type A receptorGABAARsignaling in non neuronal cellsOur research has demonstrated that ligands activating GABAAR subtypes located on airway smooth muscle and immune cells reduce airway hyper responsivenessAHRand inflam ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Accelerated Minimally Invasive Brain Clot Evacuation Using Guided Drug Delivery

    SBC: InseRT            Topic: 105

    SignificanceWe propose to extend and customize inseRT MRI s Real Time MR image guided surgical platformoriginally developed for cerebral biopsy and direct injection cancer therapiesto overcome shortcomings in CT guidance of a promising new thrombolytic therapy for intracerebral hemorrhageICHICH is a devastating injury creating stroke like outcomes inpeople in the USA each yearDamage from mechanica ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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