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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Community Based Worksite Wellness App Linking Employees to Wellness Resources

    SBC: Vimcity, LLC            Topic: ODCDC

    There is a significantunmet needand commercialization opportunity for small business worksite wellness programs that Vimcity can providethrough a mobile technology solutionVimcity offers an innovativecommunity based web and mobile platform application to overcome small business barriers to worksite wellnessBy connecting the workforce to health promoting resources through their webbased productVimc ...

    SBIR Phase I 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  2. SBIR Phase II: Protein A Membrane Columns for Rapid Protein Purification

    SBC: Purilogics, LLC            Topic: 400

    Project Summary This SBIR Urgent Competitive Revision will develop the first affinity membrane to purify therapeutic mRNA with high selectivity and throughput. mRNA-based pharmaceuticals have potential to address a wide variety of pathologies. mRNA-based vaccines can increase safety and dramatically shorten development timelines in pandemic scenarios. A number of mRNA-based COVID-19 vaccines are u ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Novel Bio-Adhesive Mesh System for Abdominal Hernia Repair

    SBC: CIRCA BIOSCIENCE LLC            Topic: 300

    Development of a Novel Bio Adhesive Mesh System for Abdominal Hernia Repair Project Summary Abstract This project proposes the development of a novel mesh adhesive system for abdominal hernia repair utilizing surface modification of polymer surgical mesh to allow for improved tissue fixation with a poloxamine hydrogel adhesiveMore thanmillion Americans undergo hernia repair with surgical mesh each ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Developing and validating a podocyte cell-based diagnostic assay for identifying recurrent focal and segmental glomerulosclerosis patients

    SBC: InDepth Pharmaceuticals, LLC            Topic: 400

    Diagnosing glomerular diseases accurately and in timely fashion is key to developing a successful treatment plan and thereby prevent their progression to ESRDend stage renal diseaseHowevertheir successful diagnosis remains challenging due to the complex diagnostic procedures used including invasive renal biopsiesThusthere is a compelling need to develop simplified procedures to detect glomerular d ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. An Efficient System for 30-K MAS-NMR-DNP for Macromolecule Structure Determinations

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    The critical importance of solid state NMRssNMRwas recently demonstrated byafter nearly two decades of intense effortsyielding the first atomic resolution structures of the Aand Aamyloid fibrils that play acrucial role in Alzheimer s DiseaseADKey to that advance is a technique denoted as dynamic nuclearpolarizationDNPwith magic angle spinningMASFor technical reasonsdiscussed belowthese experiments ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR Phase I: Affinity membrane for rapid, high-recovery purification of gene therapy viral vectors

    SBC: Purilogics, LLC            Topic: 400

    Project Summary This SBIR Phase I project will address the need for a product that can dramatically increase the recovery and purification speed for viral vectors used in gene therapySeven thousand rare diseases that have few or no treatment options are affectingof the US populationAlthough gene therapies are promising for the treatment of many rare diseasesmost are at an early stage of developmen ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Evaluation of a Novel Connexin-Based Peptide in the Treatment of Combined Ionizing Radiation and Thermal Burn Injury

    SBC: FirstString Research, Inc            Topic: NIAID

    PROJECT SUMMARYThe threat of a nuclear attack or disaster resulting in mass casualties is of increasing concernRadiation injury frequently occurs in combination with thermal burnsCombined radiation and thermal burn injuryCRBIresults in impaired wound healingexacerbated symptomsand synergistic increases in mortalityCountermeasures that synergistically address the complex pathophysiology of CRBI at ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Ice-free vitrification and nano warming technology for banking of cardiovascular structures.

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NHLBI

    ABSTRACT This proposal focuses on translation of ice free cryopreservation by vitrification employing a novel approach of volumetric heating by nanowarming using Fe nanoparticles in an alternating electromagneticeldVitrificationsub zero storage below the glass transition temperature in aglassyrather than a crystalline frozen phaseis a form of cryopreservation that avoids ice formationVitri cation ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Identifying hereditary cancer patients in low-resource community cancer settings using an innovative informatics solution

    SBC: SGgenomics, Inc.            Topic: 101

    PROJECT SUMMARYHereditary cancer risk assessment in low resource community cancer settings is a signi cant unmet clinical needUnfortunatelymost community cancer clinics do not have adequate access to genetics expertise and patients are not systematically assessed for hereditary riskNew cost e ective and practical approaches are needed to assess and identify patients at risk for hereditary cancer c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Targeted Chelation for Reversal of Vascular Calcification

    SBC: Elastrin Therapeutics Inc.            Topic: NHLBI

    PROJECT SUMMARY Medial arterial calcification is a form of vessel hardening in which calcium deposits are found in the medial layer of elastic and muscular arteriesspecifically on elastic fibersleading to arterial stiffening and tearingAn independent risk factor for cardiovascular diseases in diabetic and chronic kidney disease patientsit predisposes the patients to cardiovascular mortality and lo ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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