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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. EMERGENCY VENTILATORY SUPPORT DEVICES BASED ON H202

    SBC: Abel Company            Topic: N/A

    THERE IS A CLEAR NEED FOR AN EMERGENCY OXYGEN DELIVERY SYSTEM THAT COMBINES RELIABILITY, LONG-TERM STORAGE CAPABILITY, VARIABLE AND CONTROLLABLE FLOW RATE, SMALL SIZE,SAFETY, AND SIMPLICITY OF USE. OF THE AVAILABLE OXYGEN STORAGE MEDIA, CHEMICAL SYSTEMS OFFER A REASONABLE LIKELI- HOOD OF ACHIEVING SUCH A SYSTEM. THIS PROJECT WILL INVESTIGATE THE FEASIBILITY OF USING LOW-COST HYDROGEN PEROXIDE AS T ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. OXYGEN GENERATOR FOR AMBULATORY COPD PATIENTS

    SBC: Abel Company            Topic: N/A

    THE SPECIFIC GOAL OF THIS RESEARCH IS THE DEVELOPMENT OF A PORTABLE OXYGEN SOURCE SUITABLE FOR USE IN PROVIDING SUPPLE-MENTAL OXYGEN TO INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) RESULTING FROM CHRONIC BRONCHIOLI- TIS, PULMONARY EMPHYSEMA, ASTHMA, OR CHRONIC BRONCHITIS. THE CONCEPT IS BASED ON THE USE OF A COMMON, LOW-COST, HOUSEHOLD CHEMICAL THAT GENERATES OXYGEN WHEN WATER PLU ...

    SBIR Phase II 1987 Department of Health and Human Services
  3. IN VIVO TOTAL BODY LEAD ANALYSIS BY X-RAY FLUORESCENCE

    SBC: ABIOMED, INC.            Topic: N/A

    THERE ARE AN ESTIMATED 600,000 CHILDREN UNDER SIX YEARS OLD WITH ELEVATED BLOOD LEAD LEVELS AND ONLY 5,000 PER YEAR UNDERGOING TREATMENT; AS YET, NO TECHNIQUE IS AVAILABLE TO MEASURE TOTAL BODY LEAD BURDEN. THIS PROPOSAL DESCRIBES A TECHNIQUE WHICH USES X-RAY FLUORESCENCE IN A TRANSMISSION GEOMETRY TO MEASURE THE TOTAL BODY-BURDEN OF LEAD, IN VIVO, NONINVASIVELY. A SYSTEM USING A GOLD CALIBRATION ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. DESIGN OF A PROTON MEDICAL ACCELERATOR

    SBC: Acctek Associates, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF PROTON ACCELERATORS SUITABLE FOR RADIATION THERAPY OF CANCER IN HOSPITAL OR CLINICAL SETTINGS. FOR THIS PURPOSE THE ACCELERATOR SHOULD HAVE AN ENERGY UP TO 250 MEV, AND MUST BE SIMPLE, RELIABLE, AND INEXPENSIVE COMPARED TO EXISTING ACCELERATORS FOR PHYSICS APPLICATIONS. IN ADDITION, WITH SUFFICIENT INNOVATION, IT COULD ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. ASSAY FOR PREDICTING METHOTREXATE SENSITIVITY IN HUMAN BREAST CANCER

    SBC: Aeron Biotechnology, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROPOSAL IS TO DEVELOP AN IN VITRO TEST TO IMPROVE SELECTION OF THERAPIES FOR INDIVD- UAL BREAST CANCER PATIENTS BY PREDICTING RESPONSE TO METHO- TREXATE. EXISTING ASSAYS FOR BREAST CANCER CELLS CANNOT DE-TERMINE METHOTREXATE SENSITIVITY BECAUSE OF REQUIREMENTS FORFOR FEEDER LAYERS AND MEDIUM COMPONENTS THAT CAN RESCUE SEN-SITIVE CELLS. THIS PROPOSA WILL,THEREFORE, EVAL ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. VENTRICULAR FUNCTION MONITOR FOR ACTIVE PATIENTS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    TO INCREASE THE BASIC UNDERSTANDING OF THE CARDIAC FUNCTION TO IMPROVE TECHNIQUES TO AID IN THE DIAGNOSIS OF HEART DISEASE. WE PROPOSE TO CONDUCT RESEARCH ON AN IMPROVED METHOD OF EVALUATING MYOCARDIAL FUNCTION IN ACTIVE PATIENTS. THIS APPROACH INVOLVES THE USE OF A VERY COMPACT, VESTLIKE INSTRUMENT WHICH USES NUCLEAR MEDICINE TECHNIQUES TO MEASURE THE EJECTION FRACTION OF THE HIGH VENTRICLE ON A ...

    SBIR Phase II 1987 Department of Health and Human Services
  7. NEW 2D SOLID STATE X-RAY DETECTOR FOR BIOMEDICAL RESEARCH

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    TWO DIMENSIONAL X-RAY DETECTORS ARE FINDING INCREASING USE IN DIFFRACTION STUDIES OF BIOLOGICAL MACROMOLECULES, ESPECIALLY WITH THE ADVENT OF HIGH INTENSITY X-RAY SOURCES AND COMPUTER AIDED ANALYSIS SYSTEMS. CURRENTLY AVAILABLE DETECTORS ALL SUFFER FROM PERFORMANCE LIMITATIONS, MAINTENANCE REQUIREMENTS AND/OR EXORBITANT COSTS. THE PROPOSED RESEARCH IS AIMED AT THE DEVELOPMENT OF A LARGE AREA SINGL ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. COMPUTER CONTROLLED COLLIMATORS FOR RADIATION THERAPY

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    ONE OF THE MOST IMPORTANT CRITERIA FOR SUCCESSFUL RADIATION THERAPY IS THE ABILITY TO DELIVER THE HIGHEST POSSIBLE TUMOR DOSE AND MINIMIZE THE DOSE TO NORMAL TISSUE. MOST TECHNIQUES CURRENTLY USED FOR SHAPING RADIATION THERAPY BEAMS INVOLVE THE FABRICATION OF CUSTOM MADE, DENSE ALLOY BLOCKS. WHILE THESE BLOCKS HAVE PROVEN TO BE RELATIVELY EFFECTIVE, THEIR CONSTRUCTION IS VERY LABOR INTENSIVE AND E ...

    SBIR Phase II 1987 Department of Health and Human Services
  9. DEVELOPING/MARKETING AN ASTHMA SELF-MANAGEMENT PROGRAM

    SBC: Allergy And Asthma Consultants            Topic: N/A

    THE PURPOSE OF THIS STUDY IS THREEFOLD: PART I WILL LAST APPROXIMATELY THREE MONTHS; THE GOAL OF THIS SEGMENT WILL BE TO DEVELOP ALL COMPONENTS REQUIRED FOR A SELF-MANAGEMENT PROGRAM FOR ALL ASTHMATIC PATIENTS. THIS WILL ENTAIL, IN PART, REFINING AND VIDEOTAPING PORTIONS OF A PROGRAM WITH PROVEN EFFICIENCY, WHEEZERS ANONYMOUS. IN ADDITION, RELIABILITY AND VALIDITY OF PAPER-AND-PENCIL INSTRUMENTS U ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. WRIST ACTIVITY MONITORING FOR OUTPATIENT BEHAVIOR

    SBC: AMBULATORY MONITORING, INC.            Topic: N/A

    MOTOR EVENT FREQUENCY RECORDING, ACTIGRAPHY, IS A TECHNOLOGY USEFUL IN STUDIES OF SLEEP DISORDERS, CIRCADIAN FUNCTION, ACTIVITY PATTERNS OF ADULTS AND INFANTS, AND DEPRESSIVE DISORDERS. WIDESPREAD UTILIZATION OF THIS MONITORING TECHNOLOGY IN HEALTH APPLICATIONS HAS BEEN DELAYED BY THE LACK OF AN AFFORDABLE ACTIVITY MONITORING INSTRUMENT AND INTEGRATED SYSTEM FOR DATA MANAGEMENT, ANALYSIS, AND PRES ...

    SBIR Phase II 1987 Department of Health and Human Services

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