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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. DESIGN OF A PROTON MEDICAL ACCELERATOR

    SBC: Acctek Associates, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF PROTON ACCELERATORS SUITABLE FOR RADIATION THERAPY OF CANCER IN HOSPITAL OR CLINICAL SETTINGS. FOR THIS PURPOSE THE ACCELERATOR SHOULD HAVE AN ENERGY UP TO 250 MEV, AND MUST BE SIMPLE, RELIABLE, AND INEXPENSIVE COMPARED TO EXISTING ACCELERATORS FOR PHYSICS APPLICATIONS. IN ADDITION, WITH SUFFICIENT INNOVATION, IT COULD ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. QUANTITATION OF ESTROGEN CONCENTRATION IN CELLS

    SBC: Cell Analysis Systems Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP QUANTITATIVE ESTROGEN RECEPTOR CONCENTRATION MEASUREMENTS USING HIGH- RESOLUTION DIGITAL IMAGE MICROSCOPY TECHNIQUES. THE TECHNIQUES WILL ENABLE DIRECT MEASUREMENTS OF RECEPTOR CONCENTRATION ON A CELL-BY-CELL BASIS. THIS IS AN IMPROVEMENT OVER THE CURRENT BIOCHEMICAL ASSAYS, WHICH GIVE ONLY AN AVERAGE VALUE FOR RECEPTOR CONCENTRATION. THE QUANTITATIVE AS ...

    SBIR Phase II 1987 Department of Health and Human Services
  3. UPDATING THE TRYON MULTIVARIATE ANALYSIS COMPUTER SYSTEM

    SBC: D2 Associates            Topic: N/A

    THE PRIME LONG-TERM OBJECTIVE OF THIS PROJECT IS TO UPDATE, ENHANCE, AND DISTRIBUTE TWO COMPUTER PROGRAMS UTILIZING THE UNIQUE MULTIVARIATE ANALYSIS TECHNIQUES DEVELOPED BY THE PSYCHOLOGIST ROBERT TRYON WITH NIH SUPPORT DURING THE 1960S. ONE LONG-TERM GOAL IS TO PRODUCE AN ENHANCED ALL-FORTRAN VERSION OF A MAIN BCTRY82 SYSTEM, PORTABLE TO MOST LARGE COMPUTERS. A SECOND LONG-TERM GOAL IS TO PRODUCE ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. DEVELOPMENT OF A DATABASE ON UNPROVED CANCER TREATMENTS

    SBC: I. S. Grupe, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO ESTABLISH A METHOD BY WHICH CANCER TREATMENTS NOT BEING INVESTIGATED THROUGH CONVENTIONAL CHANNELS CAN BE IDENTIFIED, ORGANIZED INTO A DATABASE, AND DISSEMINATED TO INTERESTED PARTIES. ORGANIZING THIS INFORMATION WILL PROVIDE A MEANS FOR IDENTIFYING UNSCRUPULOUS METHODS AND ALLOW THOSE TREATMENTS WITH PROMISE TO BE BROUGHT TO CLINICAL TRIALS. AN IMMEDIATE GOAL O ...

    SBIR Phase I 1987 Department of Health and Human Services
  5. DEVELOPMENT OF A SCIENTIFIC SUMMARY LANGUAGE-MEDLISH

    SBC: I. S. Grupe, Inc.            Topic: N/A

    CURRENT SCIENTIFIC BIBLIOGRAPHIC DATABASES (E.G., MEDLINE) NOW PLAY A CENTRAL ROLE IN LITERATURE ACTIVITIES. THEY ARE IMPORTANT AND THEY ARE WIDELY USED. HOWEVER, THE INFORMATION EXPRESSED IN THE TITLE, ABSTRACT, AND MESH INDEXFIELDS IN THESE DATABASES IS QUITE CHAOTIC AND SKETCHY COMPARED WITH THE STRUCTURE OF MANY OTHER KINDS OF DATABASES. BECAUSE OF THESE DEFICIENCIES, COMPUTERIZED LITERATURE S ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. RESPITE CARE FOR OLDER ADULTS ^ A PROTOTYPE

    SBC: Kin Care            Topic: N/A

    USING A FOSTER CARE MODEL, THIS RESEARCH WILL ESTABLISH A PROTOTYPE WITHIN THE PRIVATE BUSINESS SECTOR FOR OVERNIGHT RESPITE PROVISION IN PRIVATE RESIDENCES TO FRAIL OLDER ADULTS. AS NONINSTITUTIONAL SETTINGS BECOME THE PREFERRED CHOICE FOR OLDER ADULTS, DEPENDENT ADULTS AND THEIR CAREGIVERS (FAMILIES OR EQUIVALENT) INCREASINGLY UTILIZE COMMUNITY RESOURCES TO EASE CAREGIVER BURDEN AND STRESS WHICH ...

    SBIR Phase II 1987 Department of Health and Human Services
  7. CLINICIANS' KNOWLEDGE SYSTEM FOR GASTROINTESTINAL CANCER

    SBC: Knowledge Systems Inc.            Topic: N/A

    THE SPECIFIC AIMS OF THIS PROJECT ARE TO DETERMINE THE FEASIBILITY OF CREATING AN INTEGRATED KNOWLEDGE SYSTEM THAT PRACTICING PHYSICIANS CAN EASILY AND RAPIDLY ACCESS FOR INFORMATION FROM THE MEDICAL LITERATURE NEEDED TO SUPPORT THEIR DIAGNOSTIC AND THERAPEUTIC DECISIONS, AND TO ASSESS THE UTILITY TO PHYSICIANS OF SUCH A SYSTEM. THE KNOWLEDGE BASE WILL BE A COMBINATION OF CORE KNOWLEDGE, DERIVED F ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. TISSUE-EQUIVALENT MRI CARDIAC PHANTOMS

    SBC: Midwest Medical Tech            Topic: N/A

    LONG-TERM OBJECTIVES INCLUDE: (1) DEVELOPMENT OF AN INEXPENSIVE, MAGNETIC RESONANCE IMAGING (MRI) TISSUE-EQUIVALENT MATERIAL; (2) CONSTRUCTION OF MRI QUALITY ASSURANCE STANDARDS; AND (3) DEVELOPMENT OF COMPLEX TISSUE-EQUIVALENT ANTHROPOMORPHIC MRI PHANTOMS TO AID IN DETECTION OF PATHOLOGICAL CONDITIONS. THE FIRST TWO GOALS WILL BENEFIT THE HEALTH CARE INDUSTRY THROUGH THE DEVELOPMENT OF INNOVATIVE ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. DEVELOPMENT OF SURFACE COILS FOR MAGNETIC RESONANCE IMAGING

    SBC: Midwest Medical Tech            Topic: N/A

    THE SPECIFIC AIM OF THIS PROPOSAL IS TO DEVELOP A FAMILY OF SURFACE COILS FOR MAGNETIC RESONANCE IMAGING (MRI). WHEN SURFACE COILS ARE UTILIZED, MRI IMAGES SHOW IMPROVED SPATIAL RESOLUTION AND SIGNAL-TO-NOISE RATIOS. HIGH-RESOLUTION IMAGING OF THE CENTRAL NERVOUS SYSTEM, EXTREMITIES, AND PERHAPS THE CORONARY ARTERIES WILL BE POSSIBLE WITH IMPROVED SURFACE COIL DESIGN. THIS WOULD LEADTO IMPROVED DI ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. COMPUTER-CONTROLLED ELECTROPHYSIOLOGICAL INSTRUMENTS

    SBC: STOELTING COMPANY            Topic: N/A

    A LABORATORY AUTOMATION SYSTEM (LAS) FOR ELECTROPHYSIOLOGISTS WILL BE DEVELOPED. IT WILL CONSIST OF A COMPUTER-CONTROLLED NETWORK OF NINE SMART INSTRUMENTS, WHICH WOULD REPLACE THEIR CONVENTIONAL COUNTERPARTS, INCLUDING A STIMULATOR/CONTROLLER, ANALOG AND DIGITAL SWITCHING DEVICES, WAVEFORM GENERATOR, PHYSIOLOGICAL MONITOR, INTERVAL ANALYSIS SYSTEM, WAVEFORM PROCESSOR (AVERAGER), ELECTROMETER, AND ...

    SBIR Phase I 1987 Department of Health and Human Services

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