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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Language Learning Experience in Virtual Reality

    SBC: A P Ventures, LLC            Topic: 91990019R0011

    The team will develop a prototype of a virtual reality environment for high school students who are learning a foreign language. Students will become active participants in virtual scenarios using the target language of instruction (Russian in Phase I), with listening comprehension, vocabulary acquisition and recall, and grammar development occurring implicitly in simulated real-world context. At ...

    SBIR Phase I 2019 Department of EducationInstitute of Education Sciences
  2. DEVELOPMENT OF NOVEL PDE4B INHIBITORS TO TREAT ALCOHOL USE DISORDER (SBIR PHASE II)

    SBC: CODEX BIOSOLUTIONS            Topic: NIAAA

    Development of Novel PDE B Inhibitors to Treat Alcohol Use Disorder

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Increased Expression of an HIV CJ505.664 SOSIP Envelope in Plants by Modulation of ER Chaperones

    SBC: Plant Vax, Inc.            Topic: NIAID

    The recombinant HIV SOSIP EnvelopeEnvtrimer is the leading HIV vaccine candidate but current production levels are low in mammalian cell lineslikely due to current trimer designs which include numerous disulfide bondsproteolytic cleavage and extensive glycosylationknown to induce endoplasmic reticulumERstress and cellular toxicityThis proposal will utilize the Nicotiana benthamiana pN bpplant expr ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. A Low Cost Integrated Method for Isolation of M. Tuberculosis DNA from Raw Sputum

    SBC: AKONNI BIOSYSTEMS INC            Topic: NIAID

    Nucleic acid testing offers the potential to improve tuberculosis diagnosis world wideHigh purity DNA is essential to the success of virtually any downstream nucleic acid detection methodWe propose to develop a sample preparation system to extract and purify Mycobacterium tuberculosis DNA from raw sputumThe project goalas described in the solicitationPHSTopicis to develop an inexpensive and easy t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. SMALL BUSINESS INNOVATION RESEARCH (SBIR): UNIVERSAL MEDIA FOR MAINTENANCE OF MESODERMAL LINEAGE MPS SYSTEMS

    SBC: LaCell LLC            Topic: NIDA

    Microphysiological systemsMPSdevelopment has advanced as a means to reducerefineand replace animal studiesto improve models of human diseaseUsage of MPS systems for such applications will require standardization of technology componentsTowards this effortNational Center for Advancing Translational SciencesNCATSinvestigators have identified the need for a universal medium for supporting the surviva ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC #384- PHASE I (FAST TRACK) SBIR CONTRACT- FINCARE: ENABLING PROVIDERS AND PATIENTS TO MAKE INFORMED CHOICES AND MINIMIZED FINANCIAL HARDSHIP

    SBC: CARE PROGRESS LLC            Topic: NCI

    This research project seeks to create innovative software that aids healthcare providers to calculate the out of pocket costs of patients receiving cancer treatmentThe goals of this SBIR project are to leverage the insights of stakeholderssubject matter experts and industry standards to create a software system that can be integrated into the workflow of providersIf we are successfulhealthcare pro ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 385: CARE4AHEAD: CREATING A SCALABLE TECHNOLOGY SOLUTION TO IMPROVE LONG-TERM CARE FOR CANCER SURVIVORS- MOONSHOT

    SBC: CARE PROGRESS LLC            Topic: NCI

    The goal of this SBIR project is to create a prototype of an innovative software system to help cancer survivors better manage their symptoms and stay connected with their clinicians over the course of their livesThis will include enabling survivors to report symptoms they may be experiencingcollect and transmit real time measurements from wearable sensors and receive notifications and reminders t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 383: MULTI-CORE BIOPSY DEVICE WITH VOLUMETRIC FIELD OF TISSUE ACQUISITION (MOONSHOT)

    SBC: ROBIN MEDICAL INC            Topic: NCI

    The problemTumor recurrence or resistance to treatment often arises due to tumor heterogeneityThere is a need to develop smart biopsy devicesto collect biopsies from multiple tumor coresto identify locations of the biopsiesto maintain physical characteristics of tumor on the extracted samplesto be used under current image guided practicesWe propose to further develop a prototype of multi core biop ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. TOPIC #355- SBIR PHASE II- A 3D PERFUSABLE PLATFORM FOR HTS ACROSS DIVERSE RACIAL/ETHNIC CANCER SPE

    SBC: MIMETAS US, INC            Topic: NCI

    Prostate cancerPCaincidence and mortality in African American men is two times greater than men of other races ethnicities in the United StatesElucidating the underlying mechanisms for this cancer health disparityCHDis critical to patient treatment and improved patient outcomehowever there are no in vitro models available to adequately recapitulate the PCa tumor microenvironment across races ethni ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 368: TREATMENT OPTIMIZATION BY COMBINED A-EMITTER (ARPT)/RADIOTHERAPY (XRT) DOSIMETRY FOR PROSTATE CANCER PATIENTS

    SBC: RADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC            Topic: NCI

    We propose to demonstrate a cloud based software service for Combination alpha emitter radiopharmaceutical therapyRPTand external beam radiotherapyXRTCX RPTtreatment planningBoth modalities deliver radiationWe will demonstrate feasibility clinically by collecting the data needed from an existing Hopkins trial evaluating combination XRT with XofigoRa dichlorideanRPT that concentratesparticle radiat ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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