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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. NEONATAL NUTRITION AND RESONANCE IONIZATION SPECTROSCOPY

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    A PAUCITY OF KNOWLEDGE EXISTS ABOUT NEONATAL TRACE ELEMENT NUTRITION REQUIREMENTS, ESPECIALLY FOR PREMATURE INFANTS, WHOSE CRITICAL FINAL TRIMESTER ACCUMULATION OF ESSENTIAL TRACE ELEMENTS IS ABRUPTLY CEASED AT BIRTH. THE OBJECTIVE OF THIS PROPOSAL IS TO DEVELOP THE SCIENCE AND TECHNOLOGY "BRIDGE" REQUIRED TO DEMONSTRATE THE FEASIBILITY OF DIRECT, OR NEARLY DIRECT, DETERMINATION BY RESONANCE IONIZ ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. TRACE CHROMIUM IN DIABETES USING RESONANCE IONIZATION

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    TRACE ELEMENT NUTRITURE IS INCREASINGLY ACKNOWLEDGED AS A KEY ASPECT OF GROWTH, DEVELOPMENT, AND HEALTH. TRACE CHROMIUM MAY BE RELATED TO REGULATION OF INSULATION ACTION, RESTORATION OF IMPAIRED GLUCOSE TOLERANCE, AND THE CAUSAL

    SBIR Phase I 1987 Department of Health and Human Services
  3. IMAGING OF ELEMENTS IN TISSUE AT TRACE CONCENTRATIONS

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    INSTRUMENTATION ENABLING QUANTITATIVE TRACE ELEMENT-CONCENTRATION IMAGING WITH HIGH SENSITIVITY AND RESOLUTION (1 PPM, 5 ) OF BIOLOGICAL TISSUE SECTIONS OVER 2X2MM(2) WOULD BE A VALUABLE RESEARCH TOOL. SIMULTANEOUS STRUCTURAL IMAGING WOULD ENHANCE ITS UTILITY. SPUTTER-INITIATED RESONANCE IONIZATION SPECTROSCOPY (SIRIS) WILL BE ADAPTED TO PROVIDE STRUCTURAL IMAGING AND QUANTITATIVE ELEMENT-CONCENTR ...

    SBIR Phase I 1987 Department of Health and Human Services
  4. SUBPICOSECOND DESORPTION AND MASS ANALYSIS OF LARGE MOLECULES

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    EMERGING HEALTH AND MEDICAL RESEARCH PROBLEMS ARE PLACING STRINGENT REQUIREMENTS ON THE ABILITY TO CHARACTERIZE LABILEAND HIGH-MOLECULAR-WEIGHT ORGANIC COMPOUNDS. IN BIOTECHNOLOGY, FOR EXAMPLE, INTERMEDIATE SYNTHESIS PRODUCTS MUST BE IDENTIFIED. RECENT ION BOMBARDMENT DESORPTION MODELS SUGGEST THAT HIGHEST-MOLECULAR-WEIGHT COMPOUNDS WOULDDESORB MOST EFFICIENTLY THROUGH RAPID, MULTIPLE EXCITATIONS ...

    SBIR Phase I 1987 Department of Health and Human Services
  5. CHROMIUM DEFICIENCY IN INSULIN RESISTANCE

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  6. SEX SELECTION IN EMBRYO TRANSFER

    SBC: Center For Reproductive Bio            Topic: N/A

    IT IS PROPOSED TO DEVISE SEROLOGICAL METHODS FOR ROUTINE IDENTIFICATION OF MALE AND FEMALE BOVINE EMBRYOS, WITH A VIEW TO THE CONTROL OF SEX RATIO DURING COMMERCIAL EMBYRO TRANSFER. EMBRYOS WILL BE EXPOSED TO NEWLY DEVELOPED MONOCLONAL ANTIBODIES DIRECTED AGAINST MALE-SPECIFIC H-Y ANTIGEN AND THEN TO GOAT ANTIMOUSE-IG BEARING THE FLUORESCENT DYE, FITC. THE EMBRYOS WILL BE SCORED FOR LABELING UNDER ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. MOVEMENT-DETECTION SYSTEM FOR PET SCANNERS

    SBC: CTI SERVICES, INC.            Topic: N/A

    DURING A POSITRON EMISSION TOMOGRAPHY (PET) SCAN, MOVEMENT BY THE SUBJECT OF MORE THAN 1 MM WILL CAUSE NOTICEABLE BLURRING OF THE IMAGE. MOVEMENT WILL ALSO CAUSE ARTIFACTS TO BE INTRODUCED INTO THE IMAGE BECAUSE THE MATRIX FOR CORRECTING FOR GAMMA-RAY ABSORPTION IS DETERMINED FOR A SPECIFIC POSITION. THIS PROPOSAL OUTLINES THE DEVELOPMENT OF A MOVEMENT-DETECTION SYSTEM USING A SMALL ARRAY OF ULTRA ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. A SINGLE-CHIP PROCESSOR FOR TOMOGRAPHIC RECONSTRUCTION

    SBC: CTI SERVICES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  9. CARDIAC TRACER SCANS USING X-RAY-INDUCED FLUORESCENCE

    SBC: Gnl Associates Inc            Topic: N/A

    SOME OF THE MOST IMPORTANT TECHNIQUES FOR THE DETECTION OF HEART DISEASE INVOLVE THE USE OF RADIOACTIVE TRACERS. THESETRACERS YIELD INFORMATION ON CARDIAC CHAMBER VOLUMES, CARDIAC OUTPUT, EJECTION FRACTIONS, REGIONAL PERFUSION PATTERNS, AND ZONES OF FRANK TISSUE DAMAGE. GNL ASSOCIATES,INC. PROPOSES TO DEVELOP AN ALTERNATIVE TRACER TECHNOLOGY THAT DOES NOT REQUIRE THE INJECTION OF RADIONUCLIDES INT ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. A HOMOGENEOUS ASSAY FOR HEPATITIS B VIRUS SURFACE ANTIGEN

    SBC: Liposome Sciences Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services

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