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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Extended release formulation of a new IOP lowering drug for improved treatment of glaucoma
SBC: OCULO THERAPY LLC Topic: NEIGlaucoma is the leading cause of irreversible blindness in the world. Elevated intraocular pressure (IOP) is the most significant risk factor contributing to death of retinal neurons and resulting visual field loss in primary open angle glaucoma, the most common form of glaucoma. The current standard of care for glaucoma includes IOP- lowering medications delivered topically as eye drops, which de ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Advancing a Candidate Human Polyclonal Anti-Thymocyte Globulin Product Produced in Transchromosomal Bovine for Transplant Induction/Acute Rejection and T1D Therapy
SBC: SAB Biotherapeutics, Inc. Topic: NIAIDProject Summary Abstract Currently available anti thymocyte globulinATGproducts are polyclonal animal antibodiesATGAMequine polyclonal ATGThymoglobulinrabbit polyclonal ATGand have found broad use as immune tolerizing agentsparticularly for induction therapy in a majority of tissue transplantsfor acute transplant rejectionand as treatment for graft vshost disease following bone marrow transplantsE ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Identifying the precursor to oxytocin-induced uterine tachysystole by monitoring with uterine EMG
SBC: PreTel, Inc. Topic: NICHDApproximatelyof all women in the USoverannuallyare exposed to IV oxytocin at some point during labor to increase the frequency and strength of uterine contractionsOxytocin is classified as a high alert medication requiring clinical vigilanceOxytocin is generally safebut adverse outcomes arise when contractions become too frequenta condition called tachysystoleTachysystole is associated with fetal ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Expanding the Tool Box: Environmental Metabolomics Improves Decision Making and Management of Contaminated (Superfund) Sites
SBC: Microbial Insights, Inc. Topic: NIEHSProject Summary/Abstract Metabolomics is a relatively novel Molecular Biological Tool (MBT), which employs highly sensitive instrumentation to obtain a measure of all small organic molecules present in a biological sample. Contemporary MBTs rely on quantitative PCR and measure the presence and abundance of keystone bacteria (e.g., Dehalococcoides) involved in the detoxification of priority contami ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Enabling dexterous surgery at the tip of a flexible endoscope: A low-cost, disposable, steerable sheath.
SBC: ENDOTHEIA INC Topic: NIBIBProject Summary AbstractThe objective of this proposal is to perform proof of concept experiments for a new thin walledsteerable sheath that can pass through a standard colonoscope port and dexterously maneuver surgical instruments at its tipClinical significance comes from the fact that overpatients per year in the USA have unnecessaryinvasive surgery to remove a section of their colonClinical li ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Fully Human Antibody Combinations for the Prevention of Seasonal Influenza Infection
SBC: IDBIOLOGICS INC Topic: NIAIDOur overarching goal is to develop a monoclonal antibody based product for the prevention of seasonal influenza in high risk patientsIt is estimated there aredeaths annually related to seasonal influenza worldwideIn the United Statestheinfluenza season was classified a high severity season withdeathsandhospitalizations attributed to influenzaserving as a reminder of the continued severity of influ ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Mobile-phone integrated rapid diagnostic tests to improve antibiotic stewardship
SBC: Pragma Health Corp. Topic: NIAIDPROJECT SUMMARYAn estimatedbillion antibiotic prescriptions were filled in the US fromDespite a national antibiotic education campaignapproximatelyof antibiotic prescriptions are unnecessaryAs a result of the over prescription of antibioticsthere is a current and pressing public health need for improved antibiotic stewardshipCompounding this problem are new modalities of healthcare like telemedici ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a dual MDM2/XIAP inhibitor with a high therapeutic index for childhood cancers
SBC: SEAK Therapeutics, LLC Topic: NCIPROJECT SUMMARYAcute lymphoblastic leukemia (ALL) and neuroblastoma (NB) are the most common cancers in children. Currently treatment options are often associated with severe side effects. Therefore, there is a strong unmet medical need to develop targeted-drugs with higher therapeutic indexes for improved treatment outcome.The oncoproteins MDM2 and XIAP are important cell-survival proteins in tum ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR Phase I: Evaluating the feasibility of the TotalTHM-NOW for drinking water treatment plants to improve water quality, reduce costs, and lower cancer risks
SBC: Foundation Instruments, Inc. Topic: NIEHSPROJECT SUMMARY ABSTRACT Research has suggested that there is an increased risk of cancer associated with long term exposure to drinking water containing halogenated disinfection by productsDBPsTrihalomethanesTHMsare the most common class of halogenated DBPs formed during water chlorinationEvery yearthousands of drinking water treatment plantsWTPsstruggle with THMs compliance issues often allocati ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Preventing Neurovascular Matrix Degradation and Hemorrhage in Acute Ischemic Stroke
SBC: TRANSLATIONAL SCIENCES INC Topic: NHLBISeventeen million people each year suffer from an ischemic stroke and millions are left dead and disabledTreatment with recombinant tissue plasminogen activatorr tPAis only modestly effective at reducing disability and it is associated with brain hemorrhage in up toof patients when serial imaging studies are performedBrain hemorrhage causes death and disability andis the major cause of early morta ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health