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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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TOPIC 393: BREATH TEST FOR BIOMARKERS OF RADIATION EXPOSURE
SBC: MENSSANA RESEARCH INC Topic: NCIThe problemPatients receiving therapeutic radiation are at risk of adverse toxic effectsThese adverse events are usually unpredictable and may result in severe morbidity or mortalityExampleA third or more of patients receiving chest radiation for cancers of lung may develop life threatening acute radiation pneumonitisThe clinical needThere is a clinical need for an objective test to estimate the b ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Extended release formulation of a new IOP lowering drug for improved treatment of glaucoma
SBC: OCULO THERAPY LLC Topic: NEIGlaucoma is the leading cause of irreversible blindness in the world. Elevated intraocular pressure (IOP) is the most significant risk factor contributing to death of retinal neurons and resulting visual field loss in primary open angle glaucoma, the most common form of glaucoma. The current standard of care for glaucoma includes IOP- lowering medications delivered topically as eye drops, which de ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Optimal channel and lever sampling of duodenoscopes for culture using portable Two-Phase Flow technology
SBC: Novaflux Inc. Topic: NIAIDProject Summary Abstract Outbreaks associated with contaminated duodenoscopes are still occurring at high ratesRecent clinical studies evaluating patient used endoscopes reported that culture endoscope contamination rates range from andltup toExperts now recognize that there is an urgent need for an inexpensive and highly reliable sampling method to check on the adequacy of reprocessing duodenosco ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Framework for Biomolecular Optimization and Design Using a New Poisson-Boltzmann Description
SBC: CONTINUUM DYNAMICS INC Topic: 400Rational drug design holds the potential for developing more effective drugs in shorter time frames than traditional trial and error approachesAccordinglysoftware tools are needed that automate the search process and can computationally direct the changes in ligand geometry and charge distribution to selectively bind at specified receptor sitesSuch analysis entails two componentsa module that eval ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a novel therapy for mitigation of the irradiation-inducedgastrointestinal syndrome
SBC: BioIncept, LLC Topic: NIAIDAccidental radiation exposure as a result of terrorismindustrial accidentsor military actions is an increasing global threatExposure to IR in the dose range ofGy andGy toGy results in development of the hematopoieticHand gastrointestinalGIsubsyndromesrespectivelyof the acute radiation syndromeARSThe GI syndrome that follows GI ARS is the leading cause of death following higher doses of radiation e ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Tactile and ultrasound imaging fusion for functional assessment of the female pelvic floor
SBC: ADVANCED TACTILE IMAGING INC Topic: NICHDSUMMARY Pelvic organ prolapsePOPis a highly prevalent condition affecting at leastof women in the US during their lifetimesUrinary incontinenceUIas found in the US surveyaffects fromtoof womenThe true etiology of POP and UI and variations seen among individuals are not entirely understoodThese disorders are thought to share a common pathogenesisweakeningelasticity changesof the muscular and connec ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Novel fluorescent biosensors to continuously visualize real-time protein phosphorylation in live cells
SBC: Lucidicor Inc. Topic: 400Project SummaryProtein phosphorylation plays an essential role in orchestrating the myriad aspects of cell functionKinaseswhich phosphorylate proteinsare encoded byof the human genome and are critically involved in diverse conditions such as cancermetabolic disorders and neurodegenerationCurrent scientific tools for detecting cellular phosphorylation are limitedbecause most tools examine this proc ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
The use of selective NaV1.7 inhibitors to treat inflammation post-surgery
SBC: CHROMOCELL CORPORATION Topic: NIAIDABSTRACTNonsteroidal anti inflammatory drugsNSAIDsare the most commonly prescribed drugs to treat posttraumatic inflammation and painalthough they carry significant risk of seriousdose dependent adverse eventsCorticosteroidswhich are an alternative class of anti inflammatory drugsare rarely prescribed for post traumatic inflammationdue to adverse effects on wound healing and their lack of specific ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Identifying the precursor to oxytocin-induced uterine tachysystole by monitoring with uterine EMG
SBC: PreTel, Inc. Topic: NICHDApproximatelyof all women in the USoverannuallyare exposed to IV oxytocin at some point during labor to increase the frequency and strength of uterine contractionsOxytocin is classified as a high alert medication requiring clinical vigilanceOxytocin is generally safebut adverse outcomes arise when contractions become too frequenta condition called tachysystoleTachysystole is associated with fetal ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Mobile Respiratory Aid Device To Help COPD Patients Breath Easy Again
SBC: RightAir LLC Topic: NHLBIMore thanmillion Americans have such severe COPDchronic obstructive pulmonary diseasethat they cannot even climb a single flight of stairsdue to the feeling of suffocation with even minimal movementThese patients suffer like this for yearsfirst becoming essentially home boundthen chair boundand eventually bed boundThis lack of physical activity has been repeatedly shown to increase the frequency o ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health