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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Autoscreen: An innovative e-health solution for early identification of Autism Spectrum Disorder Phase II

    SBC: Adaptive Technology Consulting, LLC            Topic: 103

    PROJECT SUMMARY Early accurate identification and treatment of young children with Autism Spectrum Disorder (ASD) represents a pressing public health and clinical care challenge. Given mounting evidence that early, accurate diagnosis of ASD is possible and that very young children who receive intervention can demonstrate substantial gains in functioning, current American Academy of Pediatrics prac ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Multifunctional Semi-Powered Ankle Prosthesis: Phase II

    SBC: Synchro Motion LLC            Topic: NICHD

    PROJECT SUMMARY A conventional prosthetic ankle consists of a carbon fiber ankle-foot complex that is nominally configured to a neutral position. These prostheses generally work well for level walking and level-ground standing, but lack the adaptability to explicitly accommodate other terrain or locomotion activities, such as slope walking, slope standing, and stair ambulation. As such, common act ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Reopening the Central Airway With Needle-Size Tentacle Manipulators

    SBC: VIRTUOSO SURGICAL, INC.            Topic: NHLBI

    Project Summary/Abstract: The objective of this proposal is to create a new surgical device that provides dexterity at the tip of a rigid bronchoscope. Our new system will deliver needle-sized, tentacle-like arms through the bronchoscope port, enabling independent tissue manipulation, laser fiber aiming, and visualization, which we hypothesize will make central airway obstruction surgery safer, m ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Expanding the throughput of real-time toxicological screening of cardiac differentiation by expressing a synthetic luciferase/luciferin genetic pathway in iPSCs

    SBC: 490 BIOTECH INC            Topic: NIEHS

    Expanding the throughput of real-time toxicological screening of cardiac differentiation byexpressing a synthetic luciferase/luciferin genetic pathway in iPSCs Project Summary This Small Business Innovation Research (SBIR) Phase II project proposes to develop and validate autonomously bioluminescent induced pluripotent stem cells (iPSCs) for use in continuously data producing, reagent-free, and re ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A Molecular Diagnostic Assay for Accurately Differentiating Melanoma from Benign Lesions

    SBC: Frontier Diagnostics, LLC            Topic: 102

    Abstract. Melanoma is the third most common form of skin cancer with estimated 87,110 new cases diagnosed in the United States in the year 2017. Current routine diagnostic approaches utilize microscopic evaluation of thinly sectioned patient biopsies, but in certain cases diagnosis can be contentious even among experts. The overall goal of this multi-phase SBIR project is to develop, validate, and ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Expanding the Tool Box: Environmental Metabolomics Improves Decision Making and Management of Contaminated (Superfund) Sites

    SBC: Microbial Insights, Inc.            Topic: NIEHS

    Project Summary/Abstract Metabolomics is a relatively novel Molecular Biological Tool (MBT), which employs highly sensitive instrumentation to obtain a measure of all small organic molecules present in a biological sample. Contemporary MBTs rely on quantitative PCR and measure the presence and abundance of keystone bacteria (e.g., Dehalococcoides) involved in the detoxification of priority contami ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Non-Invasive Venous Waveform Analysis (NIVA) in patients with Heart Failure (HF)

    SBC: Volumetrix, LLC            Topic: NHLBI

    Volume overload (congestion) occurs in patients with heart failure (HF) and is the leading cause of hospitalization in the elderly worldwide. Unfortunately, clinical signs and symptoms; laboratory values; and existing diagnostic tools are unreliable in providing accurate assessment of volume status. Using a unique physiologic signal, Non-Invasive Venous waveform Analysis (NIVA), VoluMetrix has dev ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Fully Human Antibody Combinations for the Prevention of Seasonal Influenza Infection

    SBC: IDBIOLOGICS INC            Topic: NIAID

    Our overarching goal is to develop a monoclonal antibody based product for the prevention of seasonal influenza in high risk patientsIt is estimated there aredeaths annually related to seasonal influenza worldwideIn the United Statestheinfluenza season was classified a high severity season withdeathsandhospitalizations attributed to influenzaserving as a reminder of the continued severity of influ ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Mobile-phone integrated rapid diagnostic tests to improve antibiotic stewardship

    SBC: Pragma Health Corp.            Topic: NIAID

    PROJECT SUMMARYAn estimatedbillion antibiotic prescriptions were filled in the US fromDespite a national antibiotic education campaignapproximatelyof antibiotic prescriptions are unnecessaryAs a result of the over prescription of antibioticsthere is a current and pressing public health need for improved antibiotic stewardshipCompounding this problem are new modalities of healthcare like telemedici ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. SBIR Phase I: Evaluating the feasibility of the TotalTHM-NOW for drinking water treatment plants to improve water quality, reduce costs, and lower cancer risks

    SBC: Foundation Instruments, Inc.            Topic: NIEHS

    PROJECT SUMMARY ABSTRACT Research has suggested that there is an increased risk of cancer associated with long term exposure to drinking water containing halogenated disinfection by productsDBPsTrihalomethanesTHMsare the most common class of halogenated DBPs formed during water chlorinationEvery yearthousands of drinking water treatment plantsWTPsstruggle with THMs compliance issues often allocati ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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