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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Universal Fingerprinting Chips

    SBC: AMERIGENICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed Universal Fingerprinting Chips (UFCs) are microarrays of thousands of oligonucleotide probes designed to interrogate the "sequence space" occupied by essentially any genome or transcriptome. The probe sequences are selected according to specific criteria tailored to the particular application. For example, the probe length will depend on the geneti ...

    SBIR Phase I 2006 Department of Health and Human Services
  2. Bioagent Characterization by Iterative Extension

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary - A new syndrome-based diagnostic system for rapid detection and identification of category B and C priority pathogens is proposed. Phase 1 will focus on V. cholerae genes and genes from similar pathogens. The technique relies upon a helicase-driven iterative primer extension reaction (HDIE) that uses isothermal, multiplexed target amplification ...

    SBIR Phase I 2006 Department of Health and Human Services
  3. Mouse Transcriptomic Fingerprints as Biomarkers for Chronic Alcohol Abuse

    SBC: GENOME EXPLORATION, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alcohol abuse and its medical consequences have a significant negative impact on society, the economy and our health. Currently, however, no clinically available laboratory test can reliably diagnose excessive alcohol use throughout the population or predict the progression of alcohol-induced organ damage. NIAAA has therefore deemed it important to identify mor ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. OptiPush Wheelchair Training System

    SBC: MAX MOBILITY            Topic: N/A

    DESCRIPTION (provided by applicant): Wheelchair users are over twice as likely to be obese as people in the general population. The solution to obesity in the wheelchair user population is the same as it is in the general population, a healthy diet and regular exercise. The limited availability of wheelchair accessible cardiovascular exercise equipment may be contributing to lack of regular exerci ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. ErgoChair Smart Manual Wheelchair

    SBC: MAX MOBILITY            Topic: N/A

    DESCRIPTION (provided by applicant): The PVA clinical practice guidelines for preserving upper limb function following spinal cord injury recommends that wheelchair users minimize the force required to complete upper limb tasks, avoid positioning the hand above the shoulder and avoid extreme positions of shoulder internal rotation and abduction. There are several aspects of wheelchair use that le ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. Wound Healing Properties of a Non-Irritating Novel 9-cis Retinoid Acid Derivative

    SBC: MOLECULAR DESIGN INTERNATIONAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): MDI 301 is a synthetic retinoid that is similar to all-trans retinoic acid (RA) in its ability to stimulate collagen synthesis and inhibit the major collagen-degrading enzymes in skin. A major feature that distinguishes MDI 301 from RA is its lack of irritation when applied topically to skin. Recent studies from our laboratory have shown that topical treatment ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Rapid Production of PET Brain Ligands using Self Optimizing Microchemistry

    SBC: NANOTEK, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The NIH has expressed a need for focused development of PET and SPECT brain ligands as well as research and development of new technologies for radiotracer production to aid in animal and human drug research. PET compounds are powerful imaging tools, but are often difficult and slow to produce. By applying high speed microfluidic techniques, multiple PET brain ...

    STTR Phase I 2006 Department of Health and Human Services
  8. Open Architecture Image-Guided Therapy Software System

    SBC: PATHFINDER THERAPEUTICS            Topic: N/A

    DESCRIPTION (provided by applicant): One of the important developments in disease treatment over the past decade has been the development of image-guided procedures. The rise of such systems has also been associated with a contraction of the market with a few companies becoming the dominant players in the field. In such a contracted commercial state, the field does not rapidly expand but rather ha ...

    SBIR Phase II 2006 Department of Health and Human Services
  9. Commercialization of Image-Guided Liver Surgery

    SBC: PATHFINDER THERAPEUTICS            Topic: N/A

    DESCRIPTION (provided by applicant): For the past eight years, an image-guided liver surgery system has been developed by engineers and clinicians at several academic institutions, including Vanderbilt University and Washington University in St. Louis. In mid-2004, after initial investigations demonstrated that the system could be used in a clinical setting to more effectively treat liver cancer, ...

    SBIR Phase I 2006 Department of Health and Human Services
  10. High Throughput Protein Fractionation and Concentration System for MALDI-MS

    SBC: PROTEIN DISCOVERY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We describe a novel fractionation and concentration system for high throughput analysis of low abundance polypetides in serum samples by matrix-assisted laser desoption ionization (MALDI) mass spectrometry (MS). We propose to develop this polypeptide analysis system (PPAS) commercially for the rapid and reproducible purification, fractionation and concentration ...

    SBIR Phase I 2006 Department of Health and Human Services

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