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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. PlainLanguageRx: Improving Medication Labels to Reduce Health Disparities

    SBC: SAI INTERACTIVE, INC.            Topic: NIMHD

    DESCRIPTION (provided by applicant): Summary Overall, 36% of adult Americans, and 66% of Latinos, lack the level of health literacy needed to understand prescription drug information, such as the dosing instructions on medication container labels. Low health literacy and poor understanding of medication instructions are important contributors to health disparities. They lead to medication non-adh ...

    SBIR Phase I 2010 Department of Health and Human Services
  2. LUMINESCENT ANTIVIRAL DRUG DISCOVERY ASSAY

    SBC: SCI-TEC, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this SBIR Phase I project is the development of a new drug discovery platform for screening new inhibitors of viral polymerases and for studying mechanisms of action of the prospective pharmaceutical compounds. The main innovation in this project is the proposed concept of a multi-enzyme assay, which is able to measure efficiency and identify the me ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. ENZYMATIC LUMINESCENCE microRNA ASSAY

    SBC: SCI-TEC, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The goal of this project is to develop a new highly sensitive and cost effective RNA Enzymatic Luminescence Assay (qELA) for high-throughput detection and quantification of microRNA in biological samples. The assay implements the same detection concept known from pyrosequencing, yet expanding pyrosequencing detection methodology for highly sensitive and accurat ...

    SBIR Phase II 2010 Department of Health and Human Services
  4. Companion Diagnostic for ALK Mutations

    SBC: INSIGHT GENETICS, INC.            Topic: NCI

    Kinase inhibitors such as Gleevec and Tarceva have markedly improved cancer therapy. Essential to the use of such inhibitors are companion diagnostics enabling determination of the mutational status of th eir kinase targets in tumors. Anaplastic lymphoma kinase (ALK) fusion oncogenes have emerged as an important cause of lung cancer, and ALK inhibitor programs (by Pfizer, Lil ly, Ariad, Astell as, ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Islet Protection from Hypoxia Posttransplant

    SBC: BIOINVENTIONS, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Islet transplantation (ITx), especially with the emerging potential of xenotransplantation, holds significant promise for the treatment of type 1 diabetes (T1D). There are, however, major challenges that remain prior to its larger scale, cost-effective application. Hypoxia is a leading stress post-transplantation and is estimated to cause the death of approxima ...

    STTR Phase I 2010 Department of Health and Human Services
  6. An Advanced Biosensor for Molecular Interaction Studies

    SBC: MOLECULAR SENSING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Molecular interactions are central to the understanding of basic biology and cellular function, are paramount to all molecular assays (research and in vitro diagnostics), are essential in biomarker discovery and critical toward evaluating therapeutics. However, the tools available to quantify these interactions have limitations, in so far as they either rely up ...

    STTR Phase I 2010 Department of Health and Human Services
  7. OpenLIS: The Development of a Clinical Laboratory Information System Using the Op

    SBC: MOLECULAR PATHOLOGY LABORATORY NETWORK            Topic: N/A

    DESCRIPTION (provided by applicant): Current initiatives in the United States to digitize the nation's medical records are dauntingly ambitious. Achieving seamless electronic health records will require that many existing record systems as well as their feeder sources of information be reevaluated and likely reengineered. This is particularly apparent in the domain of clinical laboratory software ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Novel Methods for Dissolving Blood Clots

    SBC: Translational Sciences Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Cardiovascular disease is the leading cause of death worldwide. Current therapies for cardiovascular disease are associated with partial success, restricted access, delays, possible neurotoxicity and other important limitations. Our goal is to develop a novel therapeutic agent that is safer and more effective at dissolving the blood clots (thrombi) that cause h ...

    STTR Phase I 2010 Department of Health and Human Services
  9. NEONATAL NUTRITION AND RESONANCE IONIZATION SPECTROSCOPY

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    A PAUCITY OF KNOWLEDGE EXISTS ABOUT NEONATAL TRACE ELEMENT NUTRITION REQUIREMENTS, ESPECIALLY FOR PREMATURE INFANTS, WHOSE CRITICAL FINAL TRIMESTER ACCUMULATION OF ESSENTIAL TRACE ELEMENTS IS ABRUPTLY CEASED AT BIRTH. THE OBJECTIVE OF THIS PROPOSAL IS TO DEVELOP THE SCIENCE AND TECHNOLOGY "BRIDGE" REQUIRED TO DEMONSTRATE THE FEASIBILITY OF DIRECT, OR NEARLY DIRECT, DETERMINATION BY RESONANCE IONIZ ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. TRACE CHROMIUM IN DIABETES USING RESONANCE IONIZATION

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    TRACE ELEMENT NUTRITURE IS INCREASINGLY ACKNOWLEDGED AS A KEY ASPECT OF GROWTH, DEVELOPMENT, AND HEALTH. TRACE CHROMIUM MAY BE RELATED TO REGULATION OF INSULATION ACTION, RESTORATION OF IMPAIRED GLUCOSE TOLERANCE, AND THE CAUSAL

    SBIR Phase I 1987 Department of Health and Human Services

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