Award Data

Graspable Math Activities is web application that middle and high school students use on laptops and tablets to practice algebra and receive instantaneous feedback. Activities are based on an algebra notation technology that can promote procedural fluency while allowing students to focus on strategy and the connection between concepts and procedures. The team will produce a website that will inclu ...

This project demonstrates the technical merit, feasibility, and cost-effectiveness of a Neurological Guidance, Assessment, Goals and Engagement (NGAGE) system for people with Parkinson’s and other degenerative neurological diseases. People with Parkinson’s disease and other similar degenerative neurological diseases may be able maintain their levels of function with proper ongoing exercise pro ...

This project demonstrates the technical merit, feasibility, and cost-effectiveness of a Neurological Guidance, Assessment, Goals and Engagement (NGAGE) system for people with Parkinson’s and other degenerative neurological diseases. People with Parkinson’s disease and other similar degenerative neurological diseases may be able maintain their levels of function with proper ongoing exercise pro ...

PROJECT SUMMARY Hypoglycemiaa decrease in blood sugar levelsis a common occurrence for themillion Americans with diabetesIn severe hypoglycemiathe individual is at risk for diabetic coma and even deathAlthough these events can be managed using a glucagon emergency kitcurrent kits require a multi step procedure in which lyophilized glucagon is reconstituted and administered as an injectionEmergency ...

PROJECT SUMMARY Necrotizing enterocolitis (NEC) is a devastating disease affecting premature infants. Approximately 10% of infants born under 1500 g will develop the disease, and mortality for affected infants is 20-30%. Despite decades of research, the morbidity and mortality of the disease remain generally unchanged. Current treatment and preventive approaches for NEC remain suboptimal, with no ...

ABSTRACTUp toof low birth weight preterm infants manifest some form of periventricular white matter injuryPWMImaking it the most common form of brain injury affecting premature infantsPWMI is associated with significant morbidityas affected individuals may have profound intellectual impairment and cerebral palsyHighlighting the magnitude of PWMIeach year more thaninfants are born prematurely in th ...

PROJECT SUMMARY Almostmillion Americans currently live with Alzheimerandapos s diseaseADand this number is projected to increase tomillion byThe consensus is arising in the field that in order to treat AD effectivelyearly detection at the MCI stage is a mustThusthere is a critical need for a novel minimally invasive and cost effective diagnostic assay capable of such early detectionCell secreted e ...

PROJECT SUMMARY ABSTRACT Grating based x ray interferometric imaging has long been considered a promising technique to significantly enhance image quality at reduced radiation doseby detecting phase and scattering contrasts in addition to the absorptionX ray gratings are central components in x ray interferometersCommercially available x ray gratings have periods of andgtmwhich limits the sensitiv ...

Project Summary This proposal describes key steps towards generating the first commercial charge detection mass spectrometerCharge detection mass spectrometryCDMSis an emerging technology that can measure the masses of large heterogeneous biopharmaceuticals and nanoparticlesCurrent commercial mass spectrometers measure the mass to charge ratiom zof ensembles of ions and require charge assignment t ...

This project aims to develop NeuroManager™, an innovative neuroinformatics platform for advanced parsing, storing, aggregating, analyzing and sharing of complex neuroscience image data. A core technology that we will develop in NeuroManager will be Image Content Analysis for Retrieval Using Semantics (ICARUS), a novel, intelligent neuroimage curation system that will enable image retrieval based ...