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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. HIGH-AFFINITY MONOCLONAL ANTIBODIES FOR ENDOCRINOLOGY

    SBC: Bioquant, Inc.            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO PROVIDE FOR THE ENDOCRINE COMMUNITY A COLLECTION OF SPECIFIC MONOCLONAL ANTIBODIES (MOABS) WITH ESPECIALLY HIGH AFFINITY FOR A NUMBER OF HORMONES AND RECEPTORS BEING ACTIVELY UTILIZED IN RESEARCH. THE SPECIFIC AIM OF THIS PHASE I PROJECT IS TO DEVELOP ONE OR MORE MOABS WITH THESE CHARACTERISTICS FOR STEROID HORMONES. THE RESULTING MOABS SHOULD BE OF CO ...

    SBIR Phase I 1987 Department of Health and Human Services
  2. SOLID-PHASE ASSAY FOR SALIVA

    SBC: Bioquant, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  3. COLORIMETRIC MEASUREMENT OF MILK PROGESTERONE

    SBC: Bioquant, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  4. A RAPID, SIMPLE OVULATION TEST REQUIRING NO INSTRUMENTS

    SBC: Covalent Technology Corp.            Topic: N/A

    THERE IS A NEED FOR A SIMPLE TEST WHICH DETERMINES THE TIME OF A WOMAN'S OVULATION. THE PROJECT OBJECTIVE IS DEVELOPMENT OF A MARKETABLE TEST WHICH CAN DETECT THE HORMONAL CHANGES OCCURRING JUST PRIOR TO OVULATION. SPECIFICALLY, THE TEST WOULD DETECT EITHER ESTRONE-3-GLUCURONIDE OR LUTEINIZING HORMONE IN URINE. CTC HAS DEVELOPED A SIMPLE IMMUNOASSAY TECHNOLOGY WHICH MAY BE PERFORMED IN THE HOME, F ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. DEREPLICATION OF ANTITUMOR/CYTOTOXIC NATURAL PRODUCTS

    SBC: Derep            Topic: N/A

    THE ELIMINATION (DEREPLICATION) OF KNOWN NATURAL PRODUCTS AND DUPLICATE LEADS FROM SCREENING PROGRAMS AS EARLY AS POSSIBLE IS OF UTMOST IMPORTANCE TO ASSURE THAT MAXIMUM ATTENTION IS GIVEN TO TRULY NOVEL COMPOUNDS. THE DEVELOPMENT OF A COMPUTERIZED DATABANK IS PROPOSED. IT WILL CONTAIN INFORMATION FOR THE RAPID EXCLUSION OF KNOWN, BIOLOGICALLY ACTIVE COMPOUNDS ENCOUNTERED DURING THE SCREENING OF M ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. NEURAL DATA ACQUISITION SYSTEM FOR MULTIELECTRODE ARRAYS

    SBC: Integrated Microsystems, Inc            Topic: N/A

    MULTIELECTRODE RECORDING ARRAYS THAT EXTRACT SIMULTANEOUS NEUROELECTRIC ACTIVITY HAVE CREATED A NEED FOR A COMPUTER-BASED DATA ACQUISITION SYSTEM. THE ARRAYS INCORPORATE ON-CHIP CIRCUITRY FOR BUFFERING AND MULTIPLEXINGNEURAL SIGNALS FROM SEVERAL RECORDING SITES. THE PROPOSED SYSTEM GIVES NEUROPHYSIOLOGISTS THE CAPABILITY TO INVESTIGATE NEURAL COMMUNICATIVE PROCESSES, FORM NEURAL PROCESS NETWORK MO ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. MECHANICAL AUXILIARY VENTRICLE

    SBC: L.VAD TECHNOLOGY, INC.            Topic: N/A

    THIS PROJECT ADVANCES THE DEVELOPMENT OF A MECHANICAL AUXILIARY VENTRICLE (MAV) FOR THE TREATMENT OF INTRACTABLE CHRONIC LEFT VENTRICULAR FAILURE. THE LONG-TERM OBJECTIVE IS TO QUALIFY THE MAV SYSTEM FOR FDA APPROVAL FOR THE SYSTEM'S COMPONENTS ARE AN AVALVULAR PUMPING CHAMBER IMPLANTED IN THE DESCENDING THORACIC AORTA, AN EXTERNAL PNEUMATIC POWER SOURCE, AND A PERCUTANEOUS ACCESS DEVICE (PAD). CL ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. DEVELOPMENT OF AN IMMUNOSPECIFIC ASSAY FOR HGB A1C

    SBC: Leeco Diagnostics Inc.            Topic: N/A

    THE PRIMARY OBJECTIVE OF THIS EFFORT IS TO IMPROVE EXISTING METHODOLOGIES FOR ASSAY OF HEMOGLOBIN A1C IN HUMAN BLOOD BY UTILIZING MONOCLONAL ANTIBODY TECHNOLOGY IN THE DEVELOPMENT OF AN IMMUNOSPECIFIC ASSAY. THE CLINICAL USEFULNESS OF THE ASSAY AS AN OBJECTIVE MEASURE OF LONG-TERM CARBOHYDRATE CONTROL OF DIABETIC PATIENTS, IN MONITORING AND ENCOURAGEMENT OF PATIENT COMPLIANCE, IN REVERSAL OF CERTA ...

    SBIR Phase II 1987 Department of Health and Human Services
  9. BIOLOGICALLY STABLE HEPARIN DERIVATIVES

    SBC: Mccann Associates Inc            Topic: N/A

    A SERIES OF COVALENT HEPARIN-PROTEIN COMPLEXES WITH PROLONGED IN VIVO HALF-LIVES OF THE HEPARIN MOIETY AND HIGH ANTICOAGULANT ACTIVITY WILL BE DEVELOPED. A SERIES OF PROTEINS COVERING A BROAD RANGE OF MOLECULAR WEIGHTS AND ISOELECTRIC POINTS WILL BE CHOSEN FOR THESE CONJUGATES. VARIOUS CONJUGATION TECHNIQUES WILL BE INVESTIGATED TO DETERMINE THE METHOD THAT WILL RETAIN THE BEST ANTICOAGULANT ACTIV ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. CONTINUOUSLY VARIABLE COLLIMATOR FOR RADIATION THERAPY

    SBC: Medcyc Corp.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services

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