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FEASIBILITY IS EXAMINED FOR A HAND-HELD INSTRUMENT TO MEASURE THRUST FORCE AND JOINT MOTION DURING SPINAL MANIPULATION AND REHABILITATION OF PATIENTS WITH NEUROMUSCULAR APPLICATION TO THE HEALTH FIELD: PROVIDE NONINVASIVE MONITORING AND CONTROL OF FORCES APPLIED DURING PHYSICAL REHABILITATION PROCEDURES FOR THE BACK. THIS INSTRUMENTATION IS EXPECTED TO PROMOTE PATIENT SAFETY, ESPECIALLY THOSE AT R ...

THE AIM OF THE PROPOSED PROJECT IS TO INVESTIGATE THE FEASIBILITY OF DEVELOPING A MICROCOMPUTER-BASED EXPERT SYSTEM TO ASSIST SCIENTISTS IN SELECTING, PERFORMING, INTERPRETING, AND REPORTING STATISTICAL PROCEDURES. OFTEN RESEARCHERS IN THE HEALTH SCIENCES ARE HIGHLY COMPETENT IN THEIR SPECIFIC AREAS OF EXPERTISE BUT INADEQUATELY TRAINED IN CHOOSING AND INTERPRETING THE STATISTICS THAT ARE APPROPRI ...

THE LONG-TERM OBJECTIVE IS TO PREPARE AN EFFECTIVE LIPOSOME ENCAPSULATED REAGENT WHICH WILL BE PREFERENTIALLY TARGETED TO LIVER MACROPHAGES RESULTING IN MACROPHAGE ACTIVATION FOR THE THERAPY OF METASTATIC HEPATIC DISEASE. THE SPECIFIC AIMS ARE: 1.TO PRODUCE A LIPOPHILIC DERIVATIVE OF THE MYCOBACTERIAL CELL WALL AND INCORPORATE THAT IN LIPOSOMES DESIGNED TO BE PREFERENTIALLY TAKEN UP 2.TO DETERMINE ...

THE LONG-TERM OBJECTIVE OF THE PROPOSAL IS TO CREATE AND EVALUATE THE EFFECTIVENESS OF MONOCLONAL ANTIBODY DIRECTED AGAINST THE RECEPTOR ON MALIGNANT CELLS RECOGNIZED BY ACTIVATED MACROPHAGES. MACROPHAGES, WHEN ACTIVATED, RECOGNIZE AND DESTROY MALIGNANT CELLS. ACTIVATED MACROPHAGES DO NOT RECOGNIZE NONMALIGNANT CELLS. THE NATURE OF THIS RECEPTOR SITE IS UNKNOWN. IN THE CURRENT PHASE I PROPOSAL, US ...

THE IMPLANTS FIELD OR "SPARE-PARTS MEDICINE" IS A YOUNG (CA. 25 YEARS) HEALTH CARE ACTIVITY REQUIRING INTENSIVE INPUT FROM ENGINEERS AND MATERIALS SCIENTISTS, AS WELL AS MEDICAL DOCTORS. THE ALL-PURPOSE SYNTHETIC WHICH CAN BE USED FOR ALL MEDICAL PURPOSES HAS NOT BEEN FOUND. BIOMATERIALS ARE NEEDED FOR A WIDE VARIETY OF FUNCTIONS AND ENVIRONMENTS WITHIN THE BODY, REQUIRING A WIDE VARIETY OF PHYSIC ...

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THIS PROJECT IS A DEVELOPMENTAL STUDY TO DEFINE THE STAGES OF SEVERITY FOR SIX REHABILITATIVE CONDITIONS AND CONSTRUCT A CROSS-REFERENCE SYSTEM FOR THESE STAGED CONDITIONS WITH THEIR RESPECTIVE DIAGNOSTIC RELATED GROUPS. THE PROJECT SEEKS TO SUPPLY THE NECESSARY CONTENT AND PROTOCOL FOR PRODUCING AND DISSEMINATING A VALID TEACHING SYLLABUS TO ACCOMPANY THE NEW SYSTEM. THE METHOD WILL USE THE NOMIN ...

THE OBJECTIVES FOR THIS PROPOSED PROJECT ARE TO TEST AND MODIFY THE INTERACTIVE MICROCOMPUTER PATIENT ASSESSMENT TOOL FOR HEALTH (IMPATH) TO ENSURE TEST-RETEST RELIABILITY AND CONSTRUCT VALIDITY, AS WELL AS ESTABLISH NORMATIVE VALUES FOR BOTH A GENERAL POPULATION AND A CHRONIC LOW BACK PAIN POPULATION. THE EFFORT IS IN COLLABORATION WITH THE UNIVERSITY OF MINNESOTA AND SISTER KENNEY INSTITUTE OF M ...

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