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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. NEUROANATOMY WORKSTATION AND KNOWLEDGE ENGINEERING

    SBC: BIOGRAPHICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  2. DIMETHYLSUBERIMIDATE AS A PULPOTOMY AGENT

    SBC: Biomedical Development Corporation            Topic: N/A

    THE LONG-TERM GOAL OF THIS APPLICATION IS TO DEVELOP DIMETHYLSUBERIMIDATE (DMS) AS AN ALTERNATIVE PULP THERAPY. FORMOCRESOL, THE DRUG MOST COMMONLY USED FOR TREATMENT OF CARIOUSLY EXPOSED PULPS OF THE PRIMARY DENTITION, IS TOXIC TO THE TREATED TISSUE, INDUCES ANTIGEN FORMATION AND SUBSEQUENT CHRONIC INFLAMMATION, IS RAPIDLY DISTRIBUTED SYSTEMICALLY, AND HAS MUTAGENIC POTENTIAL. FORMOCRESOL PULPOTO ...

    SBIR Phase II 1987 Department of Health and Human Services
  3. LIPID POLYMER FILMS-A NOVEL BIOMATERIAL

    SBC: Biotechnology Associates Inc            Topic: N/A

    BIOTECHNOLOGY ASSOCIATES, INC. WILL DEVELOP SURFACE COATINGS COMPOSED OF FILMS OF POLYMERIZED LIPIDS THAT WILL BE NONTHROMBOGENIC AND NONADHESIVE FOR CELLS. THUS THEY MAY PROVIDE USEFUL BIOCOMPATIBLE COATINGS FOR BIOMEDICAL DEVICES. LIPID POLYMER FILMS WILL ALSO BE MODIFIED BY COUPLING OF ADHESION PROTEINS OR PEPTIDES TO PROVIDE SURFACES WITH CONTROLLED CELL ADHESION PROPERTIES IN THE ABSENCE OF S ...

    SBIR Phase I 1987 Department of Health and Human Services
  4. GASTROINTESTINAL ENDOSCOPIC OPTICAL FIBER FLUORIMETRY

    SBC: I.v.p. Company            Topic: N/A

    RESEARCH ON NOVEL GASTROINTESTINAL ENDOSCOPIC OPTICAL FIBER FLUORIMETRY (GEOFF) SENSORS IS PROPOSED IN ANSWER TO THE EMPHATIC NEED FOR SIGNIFICANT GAINS IN NEW AND BETTER SENSORDEVICES IN CONNECTION WITH RESEARCH, DIAGNOSTIC, AND THERAPEUTIC ENDOSCOPIC PROCEDURES. THE MERITS OF PROMISING SINGLE- OR MULTI-STRANDED AND DISPOSABLE OPTICAL FIBER FLUORIMETRY SENSORS CONFIGURED TO AUGMENT THE FIBEROPTIC ...

    SBIR Phase I 1987 Department of Health and Human Services
  5. TOXIC PEPTIDES AS IMMUNOTOXIN COMPONENTS

    SBC: Inland Laboratorytories            Topic: N/A

    IMMUNOTOXINS COMBINE THE ACTIVITY OF A POWERFUL TOXIN WITH AN ANTIBODY CAPABLE OF DELIVERING THE CONJUGATE TO A SPECIFIC TARGET CELL. THESE COMPOUNDS HAVE PROVEN EFFECTIVEIN THE IN VITRO ELIMINATION OF A NUMBER OF CELL TYPES, INCLUDING LEUKEMIA CELLS AND THE BONE MARROW CELLS IMPLICATED IN GRAFT VERSUS HOST DISEASE. IMMUNOTOXINS MAY THUS BE AN EFFECTIVE WAY OF CONTROLLING A NUMBER OF DISEASE ATTRI ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. IDENTIFYING FACILITATORS AND INHIBITORS OF BREAST SCREENING

    SBC: Institute For Org Behavior Res            Topic: N/A

    ALTHOUGH REGULAR BREAST SCREENINGS IN THE FORM OF MAMMOGRAMS AND PHYSICAL BREAST EXAMINATIONS ARE IMPORTANT FOR THE CONTROL OF BREAST CANCER, ONLY A SMALL PERCENTAGE OFWOMEN ARE RECEIVING SUCH SCREENINGS. THIS PROJECT DEALS WITH WAYS TO INCREASE THE NUMBER OF WOMEN WHO HAVE SUCH BREAST SCREENINGS. THIS PROJECT HAS THREE LONG-RANGE OBJECTIVES: (1) TO IDENTIFY THE STRENGTH OF ALL THE FACTORS THAT OP ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. GENE*DETEQ: MOLECULAR SCREENING AND ANALYSIS OF MUTATIONAL RISK

    SBC: Laboratorytories For Geneti            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  8. AN INSTRUMENT FOR AUTOMATED AUDITORY SCREENING OF THE NEWBORN

    SBC: Metraco Inc            Topic: N/A

    METRACO, INC. PROPOSES TO DEVELOP A PROTOTYPE EVOKED-POTENTIAL INSTRUMENT THAT WILL ALLOW AUTOMATED SCREENING FOR HEARING PROBLEMS IN THE NEWBORN INFANT. THE INSTRUMENT WILL PROVIDE NEW, UNIQUE FEATURES AND TECHNOLOGY UNAVAILABLE IN EXISTING INSTRUMENTS. THE MAJOR GOALS ARE: (1) TO IMPROVE THE EFFECTIVE SIGNAL-TO-NOISE RATIO AND ERROR REDUCTION ABILITY BY COMPUTATION OF THE MEDIAN RATHER THAN THE ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. THE DEVELOPMENT OF AN IMPROVED IMPLANTABLE

    SBC: MicroStrain, Inc.            Topic: N/A

    THE GOAL OF THIS PROJECT IS TO PRODUCE A MICRO-MINIATURE, FULLY IMPLANTABLE DISPLACEMENT SENSOR, CAPABLE OF CHRONIC IMPLANTATION IN VIVO. THE DEVICE WILL INCORPORATE SEVERAL NEW FEATURES THAT ENHANCE THE GENERAL USEFULNESS OF THE SENSOR. THE DEVICE IS BASED ON THE PRINCIPLE OF DETECTION OF THE PROXIMITY OF A MAGNET BY A HALL-EFFECT SENSOR. PHASEI OF THE STUDY IS DESIGNED TO (1) TEST AND IMPROVE TH ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. COMPUTER-CONTROLLED X-RAY IMAGE ANALYZER

    SBC: Rad-image Corp            Topic: N/A

    RAD-IMAGE CORPORATION PROPOSES TO DEVELOP A PORTABLE, MICROCOMPUTER-CONTROLLED SCANNING DIGITIZER AND AUXILIARY DEVICES TO MEASURE: (1) X-RAY TARGET INTENSITY DISTRIBUTIONSDIRECTLY; (2) LIGHT INTENSITY DISTRIBUTIONS FROM FLUORESCENTSCREENS, IMAGE INTENSIFIERS, AND BACKLIGHTED, DEVELOPED X-RAY FILMS; AND (3) KILOVOLTAGE, X-RAY EXPOSURE, HALF-VALUELAYERS, AND TIME OF EXPOSURE. IT IS ALSO PLANNED TO ...

    SBIR Phase I 1987 Department of Health and Human Services

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