Award Data

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CURRENTLY, AN ASSAY TO MEASURE THE RATE OF BONE RESORPTION IN AN EASY AND REPRODUCIBLE MANNER DOES NOT EXIST. OSTEOCALCIN, A BONE-SPECIFIC PROTEIN, IS ASSAYED AS A MARKER OF BONE FORMATION. SINCE THERE IS REASONABLE EVIDENCE THAT FRAGMENTS OF BONE PROTEINS ARE LIBERATED BY THE RESORPTIVE PROCESS, AN ASSAY OF OSTEOCALCIN FRAGMENTS SHOULD ALLOW AN ASSESSMENT OF RESORPTION. THIS, WHEN COUPLED WITH AS ...

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THE GOAL OF THIS PROJECT IS TO DEVELOP A HIGH-QUALITY, LOW-COST, SAFE, AND EASY-TO-USE WHEELCHAIR-BASED EXERCISE MACHINE. THE MACHINE WILL BE ESPECIALLY USEFUL FOR INDIVIDUALS WHO ARE NOT ABLE TO GET OUT OF A WHEELCHAIR ON THEIR OWN. IT WILL PROVIDE CONTINUOUS PASSIVE MOTION OF THELEGS, ARMS, AND TORSO AT VARIABLE RATES, AND ALSO ALLOW VOLUNTARY MUSCLE CONTRACTIONS TO BE PERFORMED SIMULTANEOUSLYWI ...

DYSLEXIA AFFECTS MILLIONS OF CHILDREN AND ADULTS. THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP, TEST, AND MARKET SOFTWARE DESIGNED TO REMEDIATE DYSLEXIA. NO SUCH PRODUCT CURRENTLY EXISTS. DURING PHASE I, A PROTOTYPE READING PROGRAM WILL BE PRODUCED BASED ON INSTRUCTIONAL CONTENT SPECIFIED WITH CONSULTANTS MARION BLANK AND ISABELLE LIBERMAN, BOTH WELL-KNOWN RESEARCHERS IN THE PROCESSES INVOLVED IN R ...

THE GOAL OF THIS PROJECT IS TO PRODUCE A MICRO-MINIATURE, FULLY IMPLANTABLE DISPLACEMENT SENSOR, CAPABLE OF CHRONIC IMPLANTATION IN VIVO. THE DEVICE WILL INCORPORATE SEVERAL NEW FEATURES THAT ENHANCE THE GENERAL USEFULNESS OF THE SENSOR. THE DEVICE IS BASED ON THE PRINCIPLE OF DETECTION OF THE PROXIMITY OF A MAGNET BY A HALL-EFFECT SENSOR. PHASEI OF THE STUDY IS DESIGNED TO (1) TEST AND IMPROVE TH ...

THIS PROJECT WILL PRODUCE A CORDLESS OPTICAL INPUT DEVICE THAT WILL GIVE THE SEVERELY DISABLED PERSON A COMMUNICATION AID AND ACCESS TO USE OF THE MICROCOMPUTER. THE DEVICE TRANSMITS SHORT PULSES OF INFRARED LIGHT TOWARD THE USER THAT ARE REFLECTED BACK BY A REFLECTOR WORN BY THE USER. A CAMERA MEASURES THE REFLECTOR'S ROTATION AND POSITION CHANGES AND SENDS THEM TO THE COMPUTER. A POP-UP KEYBOARD ...

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EPIDEMIOLOGIC AND CLINICAL STUDIES HAVE DOCUMENTED THE HIGH PREVALENCE OF LIGAMENTOUS TISSUE INJURY AMONG ATHLETES AND OTHER INDIVIDUALS ENGAGED IN VARIOUS SPORTING ACTIVITIES. TREATMENT OF THESE INJURIES BY AUGMENTING OR REPLACING INJURED TISSUE WITH OTHER TISSUE FROM THE BODY HAS NOT BEEN SUCCESSFUL. FOR THIS REASON, ATTENTION HAS SHIFTED TO DEVELOPMENT OF PROSTHETIC LIGAMENTS. A POTENTIAL CANDI ...

This project aims to develop NeuroManager™, an innovative neuroinformatics platform for advanced parsing, storing, aggregating, analyzing and sharing of complex neuroscience image data. A core technology that we will develop in NeuroManager will be Image Content Analysis for Retrieval Using Semantics (ICARUS), a novel, intelligent neuroimage curation system that will enable image retrieval based ...