Award Data

This project aims to develop NeuroManager™, an innovative neuroinformatics platform for advanced parsing, storing, aggregating, analyzing and sharing of complex neuroscience image data. A core technology that we will develop in NeuroManager will be Image Content Analysis for Retrieval Using Semantics (ICARUS), a novel, intelligent neuroimage curation system that will enable image retrieval based ...

We are working on a new approach to treating acute arthritis based on a common pathway in the cellular infiltrates that damage bones and jointsInflammatory arthritis disables thousands of people each yearIt occurs in children and adultsafter trauma and infections but most cases are idiopathicMillions of adults live with chronic RAwhich has similar featuresInflammatory arthritis often requires trea ...

ABSTRACT The goal of this Fast-Track STTR project is to optimize and test a novel arm restraint in older critically ill mechanically ventilated patients that increases mobility; reduces agitation, use of sedative medications, and delirium; and exhibits high satisfaction and acceptability among hospital staff, family members, and patients. Older mechanically ventilated patients are often immobilize ...

DESCRIPTION: The Multi Component Intra Ocular Lens (MC-IOL) represents a new concept in intraocular lens technology which allows surgical adjustment of the postoperative refractive state of the eye. In contrast to the conventional, single element IOL, the MC-IOL has three optical components: the Base lens which is placed permanently in the eye (in the capsular bag) ...

The partial opioid agonist buprenorphine, is expected to be approved by the FDA in the very near future for the treatment of opioid-dependence and will be available via physician prescription, enabling a greatly needed expansion of access to opioid treatment services. However, physicians, because of considerable dema ...

DESCRIPTION: We will develop a neuroinformatics system that will allow neuroscientists to collect extremely large images of microscopic specimens at the highest magnification of a light microscope, to store them in a web-enabled database, and to share them with colleagues and students over the Internet and intranets. Once collected, these extremely large images will ...

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THE GOAL OF THIS PROJECT IS TO PRODUCE A MICRO-MINIATURE, FULLY IMPLANTABLE DISPLACEMENT SENSOR, CAPABLE OF CHRONIC IMPLANTATION IN VIVO. THE DEVICE WILL INCORPORATE SEVERAL NEW FEATURES THAT ENHANCE THE GENERAL USEFULNESS OF THE SENSOR. THE DEVICE IS BASED ON THE PRINCIPLE OF DETECTION OF THE PROXIMITY OF A MAGNET BY A HALL-EFFECT SENSOR. PHASEI OF THE STUDY IS DESIGNED TO (1) TEST AND IMPROVE TH ...

DYSLEXIA AFFECTS MILLIONS OF CHILDREN AND ADULTS. THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP, TEST, AND MARKET SOFTWARE DESIGNED TO REMEDIATE DYSLEXIA. NO SUCH PRODUCT CURRENTLY EXISTS. DURING PHASE I, A PROTOTYPE READING PROGRAM WILL BE PRODUCED BASED ON INSTRUCTIONAL CONTENT SPECIFIED WITH CONSULTANTS MARION BLANK AND ISABELLE LIBERMAN, BOTH WELL-KNOWN RESEARCHERS IN THE PROCESSES INVOLVED IN R ...

A MAJOR CONCERN IN ENVIRONMENTAL AND OCCUPATIONAL AIR POLLUTION IS THE HAZARD POSED BY SUSPECTED CARCINOGENS. WHEREAS MOST PREVIOUS RESEARCH HAS FOCUSED ON CONCENTRATIONS OR BIOASSAYS OF SPECIFIC CHEMICAL AGENTS, THE PROPOSED DEVELOPMENT OF THE ""C-PROBE'' DIRECT PASSIVE MONITOR OFFERS A GREATLY SIMPLIFIED MEANS TO DETECT THE BIOLOGICAL ACTIVITY OF UNSPECIFIED AGENTS WHICH MAY REFLECT THEIR CARCIN ...