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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Personalizing Speech Output for Communication Devices

    SBC: AGORA NET INC            Topic: N/A

    DESCRIPTION (provided by applicant): ModelTalker is a text-to-speech synthesis (TTS) system intended to be of particular interest to potential Augmentative and Alternative Communication (AAC) device users. Most present AAC devices use TTS software that derives from rule-based formant synthesis algorithms developed in the 1970s, but modern concatenative synthesis systems (of which ModelTalker is an ...

    STTR Phase I 2003 Department of Health and Human Services
  2. New Materials for Plague Antigen and Antibody Detection

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop novel soluble sensing materials that can be used in homogenous fluorescence assays for the detection of Yersinia pestis antigens and antibodies. Y. pestis is the etiological cause of plague and a potential biowarfare agent. The sensing materials are solutions of functionalized liposomes that become fluorescent when they bind selectively t ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. New Tracking Approach for 3D Vascular Ultrasound

    SBC: ASCENSION TECHNOLOGY CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Ultrasound is widely used for imaging of blood vessels because it is non-invasive, real-time, and relatively inexpensive. Reliable quantitative evaluation of blood vessels plays a pivotal role in cardiovascular disease diagnosis and follow-up intervention to avoid progression to life or limb-threatening stages. These studies require accurate vessel measureme ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Polymers for Infection Resistant Urinary Catheters

    SBC: CCL Biomedical Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Hospital acquired infections are on the increase and compromise the quality and cost-effectiveness of health care. A significant number of device-associated infections occur with urinary catheters. New and effective strategies to supplement and complement traditional infection control practices are urgently needed. Ideally, new technologies should display br ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. Field Expansion Prism Glasses for Homonymous Hemianopia

    SBC: CHADWICK OPTICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The broad, long term objective of this proposal is to overcome optical design, ergonomical, and cosmetic obstacles that stand in the way of innovative lens designs for low vision enhancement. Specifically, we have chosen to carry forward the work on field expansion for Homonymous Hemianopia proposed by Dr. Eli Peli of the Schepens Eye Research Institute. The d ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Enhanced Oxygenation of Bioreactors

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will significantly enhance bioreactor product Mty by significantly increasing the bubbleless oxygen delivery to bioreactors. Sales of major biopharmaceuticals currently exceed $18 billion. Oxygen limitations often control cell growth and viability and therefore product titer. Sparging is extensively used to oxygenate fermentation broths using ad ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Enhanced Ozone Disinfection of Biofilms in Waterlines

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dental Unit Waterlines have come under increasing scrutiny as residents of biofilms which harbor and release bacteria and in some instances harmful pathogens. As a result ADA has pro actively recommended that the water delivered by dental equipment have 3 mg per liter) can remove all of the planktonic bacteria and reduce biofilm levels by 99.99%. This suggerts ...

    SBIR Phase II 2003 Department of Health and Human Services
  8. Enhanced Ozone Disinfection of Biofilms in Waterlines

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dental Unit Waterlines have come under increasing scrutiny as residents of biofilms which harbor and release bacteria and in some instances harmful pathogens. As a result ADA has pro actively recommended that the water delivered by dental equipment have 3 mg per liter) can remove all of the planktonic bacteria and reduce biofilm levels by 99.99%. This suggerts ...

    SBIR Phase I 2003 Department of Health and Human Services
  9. Concentration Method for Thermally Labile Pharmaceutical

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Freeze-drying is commonly employed to concentrate temperature-sensitive pharmaceuticals. Freeze-drying is expensive and causes product degradation. Osmotic distillation (OD) is a candidate for gentler and lower-cost concentration but has not been commercially developed because microporous membranes fail due to wet-out. In Phase I, Compact Membrane Systems (C ...

    SBIR Phase II 2003 Department of Health and Human Services
  10. Concentration Method for Thermally Labile Pharmaceutical

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Freeze-drying is commonly employed to concentrate temperature-sensitive pharmaceuticals. Freeze-drying is expensive and causes product degradation. Osmotic distillation (OD) is a candidate for gentler and lower-cost concentration but has not been commercially developed because microporous membranes fail due to wet-out. In Phase I, Compact Membrane Systems (C ...

    SBIR Phase I 2003 Department of Health and Human Services

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