Award Data

ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

Mucormycosis is one of the deadliest of the invasive fungal infections. Mucormycosis occurs most often in patients with hematological malignancies undergoing chemotherapy, patients who have received hematopoietic stem cell transplants or patients with diabetes mellitus. Improved diagnosis is the most frequently noted unmet need for management of the mucormycosis patient. Delays in treatment increa ...

1 PROJECT SUMMARY2 This application for a Phase II SBIR award extends the successful completion of Phase I and represents a 3 collaboration between Clinitech, LLC and McLean Hospital/Harvard Medical School to continue the4 development of a wearable biosensor for detecting alcohol in the interstitial fluid of humans. Excessive use of5 alcohol accounts for much of the public health burden related to ...

This project aims to develop NeuroManager™, an innovative neuroinformatics platform for advanced parsing, storing, aggregating, analyzing and sharing of complex neuroscience image data. A core technology that we will develop in NeuroManager will be Image Content Analysis for Retrieval Using Semantics (ICARUS), a novel, intelligent neuroimage curation system that will enable image retrieval based ...

Tinea capitis (ringworm of the scalp) and onychomycosis (fungal nail infection) are infections that are most often caused by dermatophytes of the fungal genera Trichophyton and Microsporum. These two infections affect approximately 14 million people in the U.S. each year. Dermatophyte infections of the hair and nails are treated with oral antifungals for up to 12 weeks. Due to potential adverse ef ...

ABSTRACT The goal of this Fast-Track STTR project is to optimize and test a novel arm restraint in older critically ill mechanically ventilated patients that increases mobility; reduces agitation, use of sedative medications, and delirium; and exhibits high satisfaction and acceptability among hospital staff, family members, and patients. Older mechanically ventilated patients are often immobilize ...

DESCRIPTION (provided by applicant): We propose the Orion workstation, an innovative, next generation microscope system that provides analysis tools for fully-automated quantitative change analysis in neurite outgrowth dynamics and neuronal precursor migration. The algorithms that will form the basis of this software provide information about changes seen in individual neurites and cells, yielding ...

DESCRIPTION (provided by applicant): Ongoing concerns about the management and treatment of children's pain/mood make quantitative assessment in children a high medical priority. Currently, the dominant clinical technique has children indicate only their pain by selecting from among a set of static, stylized facial expressions. Although the widespread use of such methods has yielded substantial cl ...

DESCRIPTION (provided by applicant): The objective of this Phase I proposal is to evaluate a new pain assessment method referred to as Three- Dimensional Pain Mapping. Patients use a computer method to indicate the location, intensity and depth of their pain on a model of the human body. The model can be rotated by the patient in order to obtain the most advantageous viewpoints for marking pain. A ...

Location 1860 WENDY WAY RENO, NV 89509 United States N44CO200900040 $749 996.00 2 009 PHASE II TOPIC 233: AUTOMATED PROCESSING OF CANCER-RELATED DATA Department of Health and Human Services National Institutes of Health SBIR PHS2009-1 QUANTUMMARK LLC Phas ...