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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Discovery of T-type Calcium Channel Antagonists from Multicomponent Reactions and Their Application in Paclitaxel-induced Peripheral Neuropathy

    SBC: Regulonix            Topic: 101

    Summary Abstract Chemotherapy induced peripheral neuropathyCIPNis detected inof cancer patients during all phases of cancerSensory symptoms in the hands and or feettypically in astocking glovepatternare commonand manifested as painnumbnessand or tinglingCIPN can result in chemotherapy dose reduction or discontinuationand can also have long term effects on the quality of lifeThe course of CIPN can ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Continuing Preclinical Development of PPCM Vaginal Contraceptive MPT to IND

    SBC: YASO THERAPEUTICS INCORPORATED            Topic: NICHD

    Women in all economic, social, and cultural circumstances suffer from high rates of unplanned pregnancy, along with a high prevalence and incidence of sexually transmitted diseases. Trends in the United States and lesser developed economies are going in the wrong direction. The availability of a single multipurpose prevention product (MPT) that prevents both unplanned pregnancy and one or more of ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Automated objective outcome measures for clinical use in dysarthria

    SBC: Aural Analytics LLC            Topic: NIDCD

    AbstractSummary The inability to engage in spoken communication is among the most debilitating of all human conditionsIn the field of communication disordersa speech language pathologist sSLP sperceptual evaluation of the quality of speech production is the gold standard for assessment and for documenting treatment progressHoweverdecades of research has confirmed that auditory perceptual judgments ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Glioblastoma multiforme therapy via telomerase reverse transcriptase (hTERT) down-regulation. Molecular chaperones redirect quadruplex folding to reverse the effect of hTERT gene promoter mutations.

    SBC: Reglagene, LLC            Topic: 106

    Project Summary Overexpression of hTERT is a hallmark of cancer and is associated with oncogenesistumor maintenanceand resistance to conventional chemotherapyElongated telomeres at the ends of chromosomes are a hallmark for cancer in the early stage of tumorigenesis and are associated with genetic instabilityAs a consequencesuppressed telomerase in normal cells is highly activated to immortalize t ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Therapeutic Antibody Targeting of Extracellular NAMPT in Ventilator-Induced Lung Injury (VILI)

    SBC: AQUALUNG THERAPEUTICS, CORP            Topic: NHLBI

    PROJECT SUMMARYMortality rates in intensive care unitsICUsare unacceptably high and are directly related to the duration of mechanical ventilation that is required to support patients with respiratory failureFor exampleacute respiratory distress syndromeARDSis a vexing acute inflammatory lung disease requiring mechanical ventilatory support as the result of severe hypoxemia and respiratory failure ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Phase II- HazPrep Worker Training- Community Risk Profile- COVID-19 Rapid Response

    SBC: INXSOL LLC            Topic: 142

    PROJECT SUMMARY/ABSTRACT COVID-19 Supplement to HazPrep Phase II. Original Summary: A workerandapos;s personal hazard profile (PHP) is a function of hazards present and his/her exposure level to those hazards. Workers with an elevated level of risk are those who can be engaged in activities related to - or working around - hazardous materials, waste generation, removal, containment, transportation ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Goldmann Contact Tonometry with Optimized Error Correction

    SBC: CATS TONOMETER LLC            Topic: NEI

    Intuor Technologies, LLC - Project Summary Goldmann Contact Tonometry with Optimized Error Correction Intraocular pressure (IOP) measurement is a very important criteria used to assess visual acuity when eye care professionals are diagnosing, treating, and managing potential glaucoma patients. Goldman tonometry (GAT) IOP is recognized as the “gold standard”, but GAT IOP measurements errors hav ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development and Assessment of an Engineered Cardiac Tissue for Treating Dilated Cardiomyopathy

    SBC: Avery Therapeutics, Inc            Topic: NHLBI

    Abstract Non ischemic dilated cardiomyopathyDCMis a progressive disease that causes global left ventricularLVand right ventricularRVdysfunction leading to heart failure and deathThe prognosis for non ischemic DCM is poorwith data suggesting close toyear mortality without a heart transplantThe prevalence iscasespopulation year with a high incidence in patients andltyears oldThe treatment includes a ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Enabling Toxoplasma gondii Kinome Directed Drug Discovery

    SBC: LUCEOME BIOTECHNOLOGIES, L.L.C.            Topic: NIAID

    Project Summary Toxoplasmosis is caused by a single celled apicomplexanToxoplasma gondiiT gondiiwhich invades host cells through ingestion of uncooked infected meat or contaminated waterT gondii infectsof the world s population and the current cost of the disease in US itself is estimated to be $ B and risingCurrent treatment regimen is effective only against acute infection and has severe side ef ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development of an automated healthcare system for effective management of patients with chronic diseases

    SBC: Advinow, Inc.            Topic: NINR

    PROJECT SUMMARYCare delivery at primary and urgent clinics is critically hindered by doctor shortagetime constraints and the inappropriate use of infrastructuresRising aging population and unhealthy lifestyle are expected to drive the increase of chronic disease and the national health expenditures associatedof the U Sgross domestic product byTelemedicine has been proposed as a possible solution t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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