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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Person-Centered Planning ToolKit: Development of an Application to Improve Workforce Participation Through Team Collaboration and Customized Employment Discovery Technology

    SBC: Assistech Systems LLC            Topic: Disabilities

    This project addresses the need for increased opportunities for customized employment for individuals with cognitive disabilities by developing the Person-Centered Planning ToolKit. The Toolkit will enhance implementation of personcentered planning (PCP), often limited by lack of follow-through on action items and a lack of tools to match career preferences to specific customized employment opport ...

    SBIR Phase I 2019 Department of Health and Human Services
  2. IMPROVED ULTRAFILTERS FOR BIOPROCESSING

    SBC: Abel Company            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Health and Human Services
  3. PEDIATRIC BODY LEAD BURDEN BY X-RAY FLUORESCENCE

    SBC: ABIOMED, INC.            Topic: N/A

    THREE TO FOUR MILLION YOUNG CHILDREN FROM ALL LEVELS OF SOCIETY ARE EXPOSED TO ENVIRONMENTAL SOURCES OF LEAD AT CONCENTRATIONS THAT PLACE THEM AT RISK FOR ADVERSE HEALTH EFFECTS. YET, THERE IS NO TOOL AVAILABLE FOR MEASURING TOTAL PEDIATRIC BODY BURDEN OF LEAD. THIS PROJECT WILL DEVELOP AN X-RAY FLUORESCENCE (XRF) INSTRUMENT THAT WILL ALLOW MEASUREMENT OF BODY LEAD BURDEN IN CHILDREN IN VIVO AND N ...

    SBIR Phase II 1992 Department of Health and Human Services
  4. LONG-TERM CENTRIFUGAL VENTRICULAR ASSIST DEVICE

    SBC: ABIOMED, INC.            Topic: N/A

    CENTRIFUGAL BLOOD PUMPS HAVE BEEN USED EXTENSIVELY FOR SHORT-TERM CIRCULATORY ASSISTANCE AND PERFUSION PUMPS. THEIR UTILITY FOR LONG-TERM VENTRICULAR ASSISTANCE IS LIMITED BY THROMBUS FORMATION AT THE SHAFT SEAL. ABIOMED, INC., WILL DEVELOP A MAGNETICALLY SUSPENDED CENTRIFUGAL BLOOD PUMP THAT WILL HAVE NO SHAFT SEAL AND BE SUITABLE FOR LONG-TERM CIRCULATORY SUPPORT IN EITHER AN IMPLANTED OR EXTRAC ...

    SBIR Phase II 1992 Department of Health and Human Services
  5. AN OPTIMAL LASER SOURCE FOR SMALL-DIAMETER VASCULAR ANASTOMOSES

    SBC: ABIOMED, INC.            Topic: N/A

    THIS RESEARCH WILL DEMONSTRATE THAT A NEW 1.9-MU M LASER CAN PERFORM LASER-ASSISTED VASCULAR ANASTOMOSES OF SMALL-DIAMETER VESSELS (1 TO 5 MM). THE 1.9-MU M LIGHT HAS OPTIMAL ABSORPTION CHARACTERISTICS TO ENSURE AN EVEN DEPOSITION OF ENERGY IN THE VESSEL WALL. THIS SHOULD RESULTIN A MORE DESIRED TEMPERATURE PROFILE IN THE REGION OF THE ANASTOMOSIS WHEN COMPARED WITH ALTERNATIVE SOURCES. THE PROPOS ...

    SBIR Phase II 1992 Department of Health and Human Services
  6. A PERIODONTAL TEMPERATURE AND DEPTH PROBE

    SBC: ABIOMED, INC.            Topic: N/A

    THE OBJECTIVE IS TO DEVELOP A PERIODONTAL PROBE CAPABLE OF MEASURING SITE TEMPERATURE AND POCKET DEPTH SIMULTANEOUSLY AND AUTOMATICALLY. THE PROBE IS INTENDED TO BE A RAPID SCREENING DEVICE FOR THE STATE OF PERIODONTAL HEALTH DURING ROUTINE DENTAL EXAMINATIONS. STUDIES HAVE SHOWN THAT THE INFLAMED SULCUS IS ACCOMPANIED BY ELEVATED SITE TEMPERATURES. POCKET DEPTHS ARE ROUTINELY MEASURED DURING DENT ...

    SBIR Phase II 1992 Department of Health and Human Services
  7. Field Localizaiton for Detection of Brain Generators

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Health and Human Services
  8. IMMUNODETECTION OF WOMEN AT RISK FOR PRETERM DELIVERY

    SBC: Adeza Biomedical Corpon            Topic: N/A

    IT IS THE INTENT OF THE INVESTIGATORS TO DEVELOP A NEW DIAGNOSTIC TEST FOR USE DURING PREGNANCY TO IDENTIFY WOMEN AT ELEVATED RISK FOR PRETERM DELIVERY (PTD). AN IMMUNOASSAY USING A MONOCLONAL ANTIBODY DIRECTED AGAINST ONCOFETAL FIBRONECTION (FFN), A PREGNANCY-RELATED PROTEN OF PLACENTAL ORIGIN FOUND IN THE AMNIOTIC FULID, HAS BEEN STANDARDIEZED FOR THIS PURPOSE. PRELIMINARY STUDIES HAVE SHOWN THA ...

    SBIR Phase I 1992 Department of Health and Human Services
  9. HEPATIC DIRECTED ANTIVIRAL AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    THE OBJECT OF THIS RESEARCH IS TO DEVELOP AN ANTI-HEPATITIS B VIRUS PRO-DRUG WHICH WILL CONCENTRATE IN THE INFECTED LIVER TISSUE BY BINDING THE HEPATIC ASIALOGLYCOPROTEIN RECEPTOR AND RELEASING THE ACTIVE FORM OF THE DRUG IN THE HEPATOCYTE. TOWARD THIS END, A NUMBER OF ADENOSINE ARABINOFURANOSIDE/ARABINOGALACTAN CONJUGATES WILL BE SYNTHESIZED. THE CONJUGATES WILL BE EVALUATED AS SUITABLE PRODRUGS ...

    SBIR Phase I 1992 Department of Health and Human Services
  10. RECEPTOR DIRECTED SUPERPARAMAGNETIC MRI CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    THE ULTIMATE GOAL OF THIS RESEARCH IS THE DEVELOPMENT OF TISSUE SPECIFIC, OR DIRECTED MAGNETIC RESONANCE UMAGING (MRI) CONTRAST AGENTS. THESE AGENTS WILL CONSIST OF PEPTIDES ATTACHED TO SMALL, BIODEGRADABLE SUPERPARAMAGNETIC IRON OXIDE COLLOIDS. THE BIODISTRIBUTION OF THE SUPERPARAMAGNETIC IRON OXIDE LABEL WILL BE DETERMINED BY THE PEPTIDE ON THE SURFACE OF THE IRON OXIDE AND BY THE PRESENCE OF SP ...

    SBIR Phase I 1992 Department of Health and Human Services

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