You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Algorithm to Identify Patients at Risk of Medication-Related Hospitalization

    SBC: L. KRENK, INC.            Topic: R

    The long range goal of this fast track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication related hospitalizationThe specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication related hospitalization so tha ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Network Synchrony Neurofeedback for Alcoholism

    SBC: Neurobehavioral Research, Inc.            Topic: 350

    ABSTRACT This SBIR effort is based on the idea that changes in successful Long Term AbstinenceLTAfrom alcoholism and drugs should inform treatmentOver the lastyearsour laboratory has shown adaptive changes in resting state brain network synchrony in LTA that more than reverses network synchrony differencesi eincreased appetitive drive network synchrony and decreased inhibitory control network sync ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Cross-Protective Multivalent Vaccine for Tick-Borne Flaviviruses

    SBC: HAWAII BIOTECH, INC.            Topic: NIAID

    Project Summary/AbstractThe NIH/NIAID 2017 Strategic Plan is specifically directed at promoting research that can provide solutions to mitigate the threat posed by emerging and re-emerging diseases. The tick-borne flavivirus (TBFV) group includes a number of important human pathogens that result in serious neurological or hemorrhagic diseases that are either Category B or C priority pathogens. The ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TAXOL PURIFICATION BY MONOCLONAL ANTIBODY IMMUNOADSORBENTS

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    THIS PHASE I PROJECT IS DESIGNED TO TEST THE FEASIBILITY OF PURIFYING TAXOL BY IMMUNOAFFINITY CHROMATOGRAPHY. THE USE OF THIS TECHNIQUE FOR PURIFICATION OF A LOW MOLECULAR WEIGHT COMPOUND WITH LOW AQUEOUS SOLUBILITY HAS NOT BEEN REPORTED TO DATE. TAXOL-SPECIFIC MONOCLONAL ANTIBODIES WILL BE SELECTED FOR FURTHER STUDY ON THE BASIS OF THEIR AFFINITY FOR TAXOL AND THEIR ABILITY: (I) TO BIND TAXOL IN ...

    SBIR Phase II 1993 Department of Health and Human Services
  5. Synthesis of a Taxol-Cehalosporin Prodrug

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    A Taxol prodrug derivative will be prepared. This compound will be tested for its differential cytotoxicity compared to Taxol and for its ability to be enzymatically activated. The cytotoxicity of the prodrug in combination with a monoclonal-antibody enzyme conjugate in the presence of targeted and non-targeted cells will also be examined.

    SBIR Phase I 1993 Department of Health and Human Services
  6. Light-Regulated Heterologous Expression in Neurospora

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    Regulation of gene expression is critical for cellular and organismal development, and it often plays an important role in expression of heterologous recombinant proteins. Toward development of regulated expression vectors for filamentous fungi that will minimize materials cost and manipulation of the fermentation culture, we will define cis-acting, blue light responsive regulatory elements and to ...

    SBIR Phase I 1993 Department of Health and Human Services
  7. Expression of Single-chain FV in Neurospora Crassa

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    The filamentous fungi, owing to their ability to secrete high levels of proteins, are attractive organisms for the expression and secretion of heterologous proteins of commercial and medical value. Secretion is a key element in their attraction; secretion provides the opportunity for complex proteins to fold and be processed properly and secretion will facilitate purification. Proper folding and p ...

    SBIR Phase I 1993 Department of Health and Human Services
  8. DEVELOPMENT OF POLYCLONAL SERA AND MONOCLONAL HYBRIDOMAS TO WILD TYPE MEASLES VIRUS ANTIGENS

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  9. Optimal Synthesis of Benzodiazepine Glucuronide

    SBC: Synthetic Technology            Topic: N/A

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  10. IMMUNOASSAYS FOR SAXITOXINS

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    THE SAXITOXINS ARE NEUROTOXINS AND ARE AMONG THE MOST POTENT NONPROTEIN TOXINS KNOWN. SEVERAL THOUSAND CASES OF PARALYTIC SHELLFISH POISONING OCCUR WORLDWIDE EACH YEAR, WITH A CASE-FATALITY RATE APPROACHING 10 PERCENT. SINCE THERE IS NO ANTIDOTE FOR SUCH POISONING, AVOIDANCE OF CONTAMINATED MATERIAL IS THE ONLY MEANS OF CONTROL. THE CURRENTLY ACCEPTED METHOD OF DETECTING SAXITOXIN AND ITS NATURAL ...

    SBIR Phase I 1987 Department of Health and Human Services
US Flag An Official Website of the United States Government