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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. NEEDED FIBER OPTICS FOR ENDOSCOPIC CO(2) LASER SURGERY

    SBC: Imet Corp.            Topic: N/A

    THIS PROPOSAL IS FOR THE DEVELOPMENT OF FLEXIBLE SILVER HALIDE OPTICAL FIBERS TO TRANSMIT INFRARED RADIATION OF 10.6 MICRONS FROM A CO(2) LASER WITHOUT APPRECIABLE LOSS OF POWER. PHASE I OF THE PROPOSAL IS FOR THE INVESTIGATION OF A NUMBER OF NOVEL PROCEDURES FOR THE PURIFICATION OF THE SILVER HALIDES AND FOR THE FABRICATION OF OPTICAL FIBERS FROM THIS MATERIAL.

    SBIR Phase II 1985 Department of Health and Human Services
  2. IMPROVED GEL ELECTROPHORESIS SYSTEM FOR MEDICAL RESEARCH

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    GEL ELECTROPHORESIS IS ONE OF THE MOST WIDELY USED ANALYTICAL TECHNIQUES IN MOLECULAR BIOLOGY AND GENETICS. TYPICALLY THE SEPARATION REQUIRES SEVERAL HOURS AND THE GEL IS THEN REMOVED AND ANALYZED FOR THE LOCATION OF THE DIFFERENT MOLECULAR GROUPS ON THE SURFACE AREA OF THE GEL. WHEN USED WITH RADIOISOTOPES AS LABELS, THE STANDARD PRACTICE IS TO REMOVE THE GEL AND USE IT TO EXPOSE FILM OVER 24-48 ...

    SBIR Phase II 1985 Department of Health and Human Services
  3. SWALLOWABLE ELECTRODES FOR TEMPORARY CARDIAC PACING

    SBC: Arzco Medical Electronics Inc.            Topic: N/A

    THE LONG TERM OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT AND MARKETING OF EASILY SWALLOWED ELECTRODES FOR TEMPORARY TRANSESOPHAGEAL CARDIAC PACING. THIS "PILL ELECTRODE" CAN REPLACE CARDIAC CATHETERIZATION IN A VARIETY OF DIAGNOSTIC AND THERAPEUTIC APPLICATIONS, INCLUDING INITIATION AND/OR TERMINATION OF TACHYCARDIAS, SHORT TERM MAINTENANCE OF ADEQUATE RATE IN SINUS BRADYCARDIA, ACCELERATION OF ...

    SBIR Phase II 1985 Department of Health and Human Services
  4. A ROBOTIC CONTROLLED STRENGTH TRAINING/LIMB MIMIC DEVICE

    SBC: Athtec Systems            Topic: N/A

    ASI WILL DESIGN, DEVELOP, PROTOTYPE AND EVALUATE AN INNOVATIVE STRENGTH TRAINING SYSTEM THAT INCORPORATES BOTH COMPUTER AND ROBOTIC TECHNOLOGY, TO PROVIDE VASTLY IMPROVED MUSCLE REHABILITATION THERAPY CAPABILITIES WHICH ARE NOT CURRENTLY AVAILABLE IN THE MARKETPLACE. THE INITIAL DESIGN OF THE SYSTEM IS ANTICIPATED TO BE A TWO-JOINTED ROBOTIC ARM MOUNTED ON A FLOOR-FIXED BASE. THE ROBOTIC ARM WILL ...

    SBIR Phase II 1985 Department of Health and Human Services
  5. REGULATION OF BIOLOGICAL GROWTH

    SBC: Biogrowth Inc.            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO BE ABLE TO REGULATE ABNORMAL GROWTH PROCESSES THAT ARE RELATED TO SOMATOMEDINS. AS SOMATOMEDINS ARE THE MAJOR STIMULATORS OF BONE FORMATION, THEY OFFER PROMISE IN THE THERAPY OF POST- MENOPAUSAL OSTEOPOROSIS. THEY MAY ALSO BE USED TO STIMULATEBONE FORMATION AROUND PROSTHETIC JOINTS. THE STIMULATORY PROPERTIES OF SOMATOMEDINS MAY ALSO BE IMPORTANT IN HA ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. PURIFICATION OF A BACTERIAL PROTEASE INHIBITOR

    SBC: Corptech Inc.            Topic: N/A

    THIS PROJECT IS INTENDED TO DEVELOP A PROTEASE INHIBITOR THAT CAN BE SAFELY ADMINISTERED TO PATIENTS WHO HAVE ONGOING ELASTIN DESTRUCTION AS A MAJOR FEATURE OF THEIR DISEASE. SUCH DISEASES INCLUDE THOSE IN WHICH PHAGOCYTE ACTION (INFLAMMATION) HAS OCCURRED IN CONJUNCTION WITH CONNECTIVE TISSUE TARGETS. PROMINENT AMONG THESE DISEASES ARE PULMONARY EMPHYSEMA, PNEUMONIAS, ADULT RESPIRATORY DISTRESS S ...

    SBIR Phase II 1985 Department of Health and Human Services
  7. DNA HYBRIDIZATION IN THE DIAGNOSIS OF INFECTIOUS DISEASE

    SBC: Diagnostic Hybrids Inc.            Topic: N/A

    DNA HYBRIDIZATION PROBES SPECIFIC FOR COMMON PATHOGENIC BACTERIA HAVE BEEN DEVELOPED. THE LONG TERM OBJECTIVE OF THIS RESEARCH IS THE PERFECTION OF SIMPLE PROTOCOLS AND A KIT USING DNA HYBRIDIZATION PROBES FOR THE DETECTION AND IDENTIFICATION OF PATHOGENS IN CLINICAL SPECIMENS. THE SPECIFIC AIM OF THIS PROPOSAL IS TO ASSESS THE FEASABILITY OF THIS APPROACH TO PATHOGEN IDENTIFICATION IN CLINICAL SP ...

    SBIR Phase II 1985 Department of Health and Human Services
  8. LOW COST OCR READER FOR THE VISUALLY IMPAIRED

    SBC: Energy Materials Research            Topic: N/A

    A LOW COST OPTICAL CHARACTER RECOGNITION DEVICE IS PROPOSED AS A PERIPHERAL FOR MICROCOMPUTERS. THE DEVICE IN CONJUNCTION WITH SPEECH OUTPUT WILL GIVE A LOW COST READING DEVICE AFFORDABLE BY VISUALLY IMPAIRED INDIVIDUALS. THE DEVELOPMENT STRATEGY WILL FOCUS ON A FEASIBILITY DEMONSTRATION OF A LOW COST PHOTO-DETECTOR IN CONJUNCTION WITH TRANSPORTABLE "C" CODE. THE WIDER COMMERCIAL APPLICATIONS OF T ...

    SBIR Phase II 1985 Department of Health and Human Services
  9. PRODUCTION OF COMPOSITE MONOCLONAL IMMUNOGLOBULINS

    SBC: NEUGENESIS CORPORATION            Topic: N/A

    MURINE MONOCLONAL ANTIBODIES ARE NOT USEFUL FOR REPEATED ADMINISTRATION TO MAN BECAUSE OF THE NUMBER OF FOREIGN ANTIGEN DETERMINANTS THEY CONTAIN. PRODUCTION OF HUMAN MONOCLONAL ANTIBODIES WOULD BE DESIR-ABLE FOR A VARIETY OF APPROACHES IN PROPHYLAXIS AND THERAPY OF DISEASE, AND ALSO IN PROTECTION AGAINST CONTACT WITH NOXIOUS AGENTS. WE PROPOSE DEVELOPMENT OF A PROCEDURE THAT WILL PERMIT RAPID ISO ...

    SBIR Phase II 1985 Department of Health and Human Services
  10. PORTABLE ORTHOPEDIC ELECTOMAGNETIC (POME) SYSTEM

    SBC: Geomed Inc.            Topic: N/A

    THE POEM PROGRAM WILL DEVELOP A PATIENT-ORIENTED/ LIGHT-WEIGHT PORTABLE STIMULATOR FOR TREATMENT OF HIP DISORDERS. THE PROGRAM IS DERIVATIVE OF BASIC RESEARCH IN THIS AREA OF DR'S. LECHNER 1, BASSETT (10) AND OTHERS. THE THRUST IS TO PRODUCE A SIMPLIFIED BATTERY-OPERATED EASY-TO-USE DEVICE SUITABLE FOR CLINICAL APPLICATIONS. PRESENT DEVICES ARE LINE OPERATED AND INCONVENIENT TO USE, OVER THE LONG ...

    SBIR Phase II 1985 Department of Health and Human Services

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