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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Developing EXP-1801 as an imaging agent to quantify pain and analgesia

    SBC: Expesicor Inc            Topic: NINDS

    Summary Abstract There are currently no tools available that can objectively measure painHistoricallypain in humans has been measured using subjective ratings to determine presence and severityIn animal modelspain is measured by semi quantitative assays that rely on the observation of pain behaviorsThough usefulthe inherently subjective nature of these measures has hampered both research and treat ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development and Characterization of a Preclinical Swine Model of Osteogenesis Imperfecta

    SBC: Recombinetics, Inc.            Topic: NIDCR

    PROJECT SUMMARY Osteogenesis imperfectaOIalso known asbrittle bone diseaseis a genetic disease in which patients have defects in the formationstructureor strength of their bonescausing them to break easilyOI patients exhibit impaired tissue development and bone regeneration due to inherited mutations in one of the collagen genesleading to skeletal defectsbone fragilitydentinogenesis imperfectahear ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Gra

    SBC: ASTER LABS, INC.            Topic: NCBDDD

    Abstract In this Phase II SBIR project, ASTER Labs will enhance a hands-free automatic oral hygiene device in the form of a comfortable mouthpiece that was designed and successfully tested and evaluated during a Phase I study for persons with oral hygiene disabilities and their caregivers, and then investigate the device’s efficacy in reducing dental plaque and reducing burden, thereby improving ...

    SBIR Phase II 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  4. Perfusion decellularization and recellularization for the creation of a bioengineered transplantable liver

    SBC: Miromatrix Medical Inc.            Topic: 300

    ABSTRACT Liver transplantation currently represents the only treatment for end stage liver disease (ESLD), the 8th most frequent cause of death in the United States (US). Efforts to overcome the chronic shortage of transplantable human livers include attempts at alternative organ procurement and replacement strategies. The most promising approach to date that provides the appropriate matrix compos ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Social Assistive Robot Interface for People with Alzheimer's and Other Dementias to Aid in Care Management

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: NIA

    Project Summary/Abstract Advanced Medical Electronics Corporation and our partners propose to develop a Socially-Assistive Robot (SAR) system for persons with dementia (PWD),(mild cognitive impairment, Alzheimerandapos;s disease, or other dementias), who are living in assisted living facilities. The proposed system uses Augmented Intelligence (AI) to communicate with the PWD in natural language. T ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Bariatric Mannequin System to Enable Realistic Examination Simulations of Obese Patients

    SBC: INNOVATIVE DESIGN LABS INC            Topic: 300

    Project Summary Abstract The proposed project focuses on creating a bariatric mannequin simulator to educate healthcare students on proper techniques specific and specialized to bariatric patient careSignificanceObesity is one of the world s most significant and growing health problemsMore thaninadults are overweight or have obesity and obese patients have a greater likelihood of requiring clinica ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Topical selective T-type blockers for the treatment of pruritus

    SBC: DERMAXON LLC            Topic: NIAMS

    Project SummaryAbstractPruritusalso called itchis the most frequent dermatological symptom in the US with up toof Americans being affectedPruritic stimuli are detected by a subset of nociceptive neuronspruriceptorswhich fire action potential in response to peripheral activation by THor THmolecules induced by chronic inflammatory skin diseases such as ichthyosisprurigo nodularisand hidradenitis sup ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. An optimized screening platform for identifying and quantifying biased agonists as drugs for the treatment of Opioid Use Disorder

    SBC: MONTANA MOLECULAR LLC            Topic: NIDA

    ! Project Summary Millions of Americans today have an opioid use disorderOUDMillions more misuse opioidsand the crisis continues to growThe goal of this proposal is to speed the discovery of non addictive analgesics by providing drug discovery teams with simplermore robustmore quantitativeassays for agonist biasDriven by the urgency of the problem we are seeking Fast Track support to create new as ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Miniature Passive Device for Locating Lost Dentures in Care Facilities

    SBC: ASTER LABS, INC.            Topic: NIDCR

    Abstract In this Phase II SBIR project ASTER Labs will significantly enhance an intuitive, safe, fully-embedded detection and localization solution for lost dentures. This concept was designed and successfully evaluated during Phase I with elderly denture wearers and caregivers, and tested for its accuracy and efficacy via demonstrations of successful localization of the misplaced prostheses in a ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Clinical evaluation of combination oncolytic viro-immunotherapy for solid tumors

    SBC: VYRIAD INC            Topic: 102

    PROJECT SUMMARY/ABSTRACT . Non-small cell lung cancer (NSCLC) and hepatocellular carcinoma (HCC) are leading cause of cancer death globally. Immune checkpoint inhibitors (CPIs), which block tumor immune-evasion signals and activate T-cell mediated antitumor immunity, have demonstrated clinical efficacy and are approved for several cancers including NSCLC and HCC. Despite this broad spectrum of act ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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